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Published in: Advances in Therapy 3/2020

01-03-2020 | Hemorrhoids | Original Research

Anorectal Functional Outcomes Following Doppler-Guided Transanal Hemorrhoidal Dearterialization: Evidence from Vietnam

Authors: Le Manh Cuong, Vu Nam, Tran Thai Ha, Tran Thu Ha, Tran Quang Hung, Do Van Loi, Tran Manh Hung, Nguyen Van Son, Vu Duy Kien

Published in: Advances in Therapy | Issue 3/2020

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Abstract

Introduction

Doppler-guided transanal hemorrhoidal dearterialization (THD) was considered a less invasive and innovative method to treat hemorrhoidal disease, but it may impact the anal area during dearterialization and mucopexy. Thus, this study aimed to assess any changes in anorectal manometry of grade III and IV hemorrhoidal patients following THD treatment.

Methods

This prospective observational study was conducted with patients who had grades III and IV hemorrhoidal disease. The patients were treated using THD at the Department of Surgery in the National Hospital of Traditional Medicine (Hanoi, Vietnam) between June 2012 and December 2013. Anorectal manometry was performed prior to THD and again between 6 and 12 months following the procedure.

Results

A total of 40 patients were enrolled in the study, including 32 with grade III hemorrhoids and 8 with grade IV hemorrhoids. The proportion of male patients (65%) was higher than that of female patients (35%), and the majority of patients (82.5%) were > 40 years old. The mean duration of symptoms prior to treatment was 12.3 years. The mean length of the anal sphincter was unchanged before and after THD (3.64 ± 0.40 cm prior to treatment vs. 3.66 ± 0.48 cm following treatment; p = 0.57). Significant differences in treatment-related changes were detected for all anorectal manometric measurements except maximum squeezing pressure (p < 0.05). No patient showed anal stenosis or fecal incontinence.

Conclusion

The THD technique did not change the length of the anal sphincter 6 months after hemorrhoid treatment. The values of anal pressure and rectal sensation decreased almost significantly between treatment and the follow-up visit. We suggest that further studies, which include larger sample sizes, should be conducted to confirm THD effectiveness in terms of anorectal functions.
Literature
1.
go back to reference Ratto C. THD Doppler procedure for hemorrhoids: the surgical technique. Tech Coloproctol. 2014;18(3):291–8.CrossRef Ratto C. THD Doppler procedure for hemorrhoids: the surgical technique. Tech Coloproctol. 2014;18(3):291–8.CrossRef
2.
go back to reference Ratto C, de Parades V. Doppler-guided ligation of hemorrhoidal arteries with mucopexy: a technique for the future. J Visc Surg. 2015;152(2 Suppl):S15–21.CrossRef Ratto C, de Parades V. Doppler-guided ligation of hemorrhoidal arteries with mucopexy: a technique for the future. J Visc Surg. 2015;152(2 Suppl):S15–21.CrossRef
3.
go back to reference Figueiredo MN, Campos FG. Doppler-guided hemorrhoidal dearterialization/transanal hemorrhoidal dearterialization: technical evolution and outcomes after 20 years. World J Gastrointest Surg. 2016;8(3):232–7.CrossRef Figueiredo MN, Campos FG. Doppler-guided hemorrhoidal dearterialization/transanal hemorrhoidal dearterialization: technical evolution and outcomes after 20 years. World J Gastrointest Surg. 2016;8(3):232–7.CrossRef
4.
go back to reference Giordano P, Tomasi I, Pascariello A, Mills E, Elahi S. Transanal dearterialization with targeted mucopexy is effective for advanced haemorrhoids. Colorectal Dis. 2014;16(5):373–6.CrossRef Giordano P, Tomasi I, Pascariello A, Mills E, Elahi S. Transanal dearterialization with targeted mucopexy is effective for advanced haemorrhoids. Colorectal Dis. 2014;16(5):373–6.CrossRef
5.
go back to reference LaBella GD, Main WP, Hussain LR. Evaluation of transanal hemorrhoidal dearterialization: a single surgeon experience. Tech Coloproctol. 2015;19(3):153–7.CrossRef LaBella GD, Main WP, Hussain LR. Evaluation of transanal hemorrhoidal dearterialization: a single surgeon experience. Tech Coloproctol. 2015;19(3):153–7.CrossRef
6.
go back to reference Giamundo P. Advantages and limits of hemorrhoidal dearterialization in the treatment of symptomatic hemorrhoids. World J Gastrointest Surg. 2016;8(1):1–4.CrossRef Giamundo P. Advantages and limits of hemorrhoidal dearterialization in the treatment of symptomatic hemorrhoids. World J Gastrointest Surg. 2016;8(1):1–4.CrossRef
7.
go back to reference Trenti L, Biondo S, Galvez A, Bravo A, Cabrera J, Kreisler E. Distal Doppler-guided transanal hemorrhoidal dearterialization with mucopexy versus conventional hemorrhoidectomy for grade III and IV hemorrhoids: postoperative morbidity and long-term outcomes. Tech Coloproctol. 2017;21(5):337–44.CrossRef Trenti L, Biondo S, Galvez A, Bravo A, Cabrera J, Kreisler E. Distal Doppler-guided transanal hemorrhoidal dearterialization with mucopexy versus conventional hemorrhoidectomy for grade III and IV hemorrhoids: postoperative morbidity and long-term outcomes. Tech Coloproctol. 2017;21(5):337–44.CrossRef
8.
go back to reference Cuong LM, Ha TT, Anh NN, Thanh NT, Kien VD, Lam ND. Comparison of Doppler-guided transanal hemorrhoidal dearterialization for grade III and IV hemorrhoids in Vietnam. Adv Ther. 2019;36(6):1388–97.CrossRef Cuong LM, Ha TT, Anh NN, Thanh NT, Kien VD, Lam ND. Comparison of Doppler-guided transanal hemorrhoidal dearterialization for grade III and IV hemorrhoids in Vietnam. Adv Ther. 2019;36(6):1388–97.CrossRef
9.
go back to reference Ratto C, Campenni P, Papeo F, Donisi L, Litta F, Parello A. Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: a single-center study on 1000 consecutive cases and a review of the literature. Tech Coloproctol. 2017;21(12):953–62.CrossRef Ratto C, Campenni P, Papeo F, Donisi L, Litta F, Parello A. Transanal hemorrhoidal dearterialization (THD) for hemorrhoidal disease: a single-center study on 1000 consecutive cases and a review of the literature. Tech Coloproctol. 2017;21(12):953–62.CrossRef
10.
go back to reference Haskins IN, Holzmacher J, Obias V, Agarwal S. The use of transanal hemorrhoidal dearterialization for treatment of hemorrhoid disease at a single institution. Am Surg. 2016;82(12):1160–2.PubMed Haskins IN, Holzmacher J, Obias V, Agarwal S. The use of transanal hemorrhoidal dearterialization for treatment of hemorrhoid disease at a single institution. Am Surg. 2016;82(12):1160–2.PubMed
11.
go back to reference Ratto C, Parello A, Donisi L, Litta F, Doglietto GB. Anorectal physiology is not changed following transanal haemorrhoidal dearterialization for haemorrhoidal disease: clinical, manometric and endosonographic features. Colorectal Dis. 2011;13(8):e243–5.CrossRef Ratto C, Parello A, Donisi L, Litta F, Doglietto GB. Anorectal physiology is not changed following transanal haemorrhoidal dearterialization for haemorrhoidal disease: clinical, manometric and endosonographic features. Colorectal Dis. 2011;13(8):e243–5.CrossRef
12.
go back to reference Walega P, Romaniszyn M, Kenig J, Herman R, Nowak W. Doppler-guided hemorrhoid artery ligation with recto-anal-repair modification: functional evaluation and safety assessment of a new minimally invasive method of treatment of advanced hemorrhoidal disease. Sci World J. 2012;2012:324040.CrossRef Walega P, Romaniszyn M, Kenig J, Herman R, Nowak W. Doppler-guided hemorrhoid artery ligation with recto-anal-repair modification: functional evaluation and safety assessment of a new minimally invasive method of treatment of advanced hemorrhoidal disease. Sci World J. 2012;2012:324040.CrossRef
13.
go back to reference Wanga SK, Lemeshow S. Sample size determination in health studies. A practical manual Ginebra. Geneva, Switzerland: World Health Organization; 1991. Wanga SK, Lemeshow S. Sample size determination in health studies. A practical manual Ginebra. Geneva, Switzerland: World Health Organization; 1991.
14.
go back to reference Goligher JC. Surgery of the anus, rectum and colon. 4th ed. London, UK: Bailliere Tindall; 1980. p. 924–5. Goligher JC. Surgery of the anus, rectum and colon. 4th ed. London, UK: Bailliere Tindall; 1980. p. 924–5.
15.
go back to reference Ratto C, Donisi L, Parello A, Litta F, Zaccone G, De Simone V. ‘Distal Doppler-guided dearterialization’ is highly effective in treating haemorrhoids by transanal haemorrhoidal dearterialization. Colorectal Dis. 2012;14(11):e786–9.CrossRef Ratto C, Donisi L, Parello A, Litta F, Zaccone G, De Simone V. ‘Distal Doppler-guided dearterialization’ is highly effective in treating haemorrhoids by transanal haemorrhoidal dearterialization. Colorectal Dis. 2012;14(11):e786–9.CrossRef
16.
go back to reference Xu L, Chen H, Lin G, Ge Q, Qi H, He X. Transanal hemorrhoidal dearterialization with mucopexy versus open hemorrhoidectomy in the treatment of hemorrhoids: a meta-analysis of randomized control trials. Tech Coloproctol. 2016;20(12):825–33.CrossRef Xu L, Chen H, Lin G, Ge Q, Qi H, He X. Transanal hemorrhoidal dearterialization with mucopexy versus open hemorrhoidectomy in the treatment of hemorrhoids: a meta-analysis of randomized control trials. Tech Coloproctol. 2016;20(12):825–33.CrossRef
17.
go back to reference Hoyuela C, Carvajal F, Juvany M, Troyano D, Trias M, Martrat A, et al. HAL-RAR (Doppler guided haemorrhoid artery ligation with recto-anal repair) is a safe and effective procedure for haemorrhoids. Results of a prospective study after 2-year follow-up. Int J Surg. 2016;28:39–44.CrossRef Hoyuela C, Carvajal F, Juvany M, Troyano D, Trias M, Martrat A, et al. HAL-RAR (Doppler guided haemorrhoid artery ligation with recto-anal repair) is a safe and effective procedure for haemorrhoids. Results of a prospective study after 2-year follow-up. Int J Surg. 2016;28:39–44.CrossRef
18.
go back to reference Tsunoda A, Takahashi T, Kusanagi H. A prospective randomized trial of transanal hemorrhoidal dearterialization with mucopexy versus ultrasonic scalpel hemorrhoidectomy for grade III hemorrhoids. Tech Coloproctol. 2017;21(8):657–65.CrossRef Tsunoda A, Takahashi T, Kusanagi H. A prospective randomized trial of transanal hemorrhoidal dearterialization with mucopexy versus ultrasonic scalpel hemorrhoidectomy for grade III hemorrhoids. Tech Coloproctol. 2017;21(8):657–65.CrossRef
19.
go back to reference Bharucha AE, Rao SS. An update on anorectal disorders for gastroenterologists. Gastroenterology. 2014;146(1):37–45.CrossRef Bharucha AE, Rao SS. An update on anorectal disorders for gastroenterologists. Gastroenterology. 2014;146(1):37–45.CrossRef
20.
go back to reference Wald A, Bharucha AE, Cosman BC, Whitehead WE. ACG clinical guideline: management of benign anorectal disorders. Am J Gastroenterol. 2014;109(8):1141–57.CrossRef Wald A, Bharucha AE, Cosman BC, Whitehead WE. ACG clinical guideline: management of benign anorectal disorders. Am J Gastroenterol. 2014;109(8):1141–57.CrossRef
21.
go back to reference Bharucha AE. Difficult defecation: difficult problem assessment and management; what really helps? Gastroenterol Clin N Am. 2011;40(4):837–44.CrossRef Bharucha AE. Difficult defecation: difficult problem assessment and management; what really helps? Gastroenterol Clin N Am. 2011;40(4):837–44.CrossRef
22.
go back to reference Bharucha AE, Fletcher JG, Harper CM, Hough D, Daube JR, Stevens C, et al. Relationship between symptoms and disordered continence mechanisms in women with idiopathic faecal incontinence. Gut. 2005;54(4):546–55.CrossRef Bharucha AE, Fletcher JG, Harper CM, Hough D, Daube JR, Stevens C, et al. Relationship between symptoms and disordered continence mechanisms in women with idiopathic faecal incontinence. Gut. 2005;54(4):546–55.CrossRef
23.
go back to reference Rao SS. Pathophysiology of adult fecal incontinence. Gastroenterology. 2004;126:S14–22.CrossRef Rao SS. Pathophysiology of adult fecal incontinence. Gastroenterology. 2004;126:S14–22.CrossRef
24.
go back to reference Hong YK, Choi YJ, Kang JG. Correlation of histopathology with anorectal manometry following stapled hemorrhoidopexy. Ann Coloproctol. 2013;29(5):198–204.CrossRef Hong YK, Choi YJ, Kang JG. Correlation of histopathology with anorectal manometry following stapled hemorrhoidopexy. Ann Coloproctol. 2013;29(5):198–204.CrossRef
25.
go back to reference Noelting J, Ratuapli SK, Bharucha AE, Harvey DM, Ravi K, Zinsmeister AR. Normal values for high-resolution anorectal manometry in healthy women: effects of age and significance of rectoanal gradient. Am J Gastroenterol. 2012;107(10):1530.CrossRef Noelting J, Ratuapli SK, Bharucha AE, Harvey DM, Ravi K, Zinsmeister AR. Normal values for high-resolution anorectal manometry in healthy women: effects of age and significance of rectoanal gradient. Am J Gastroenterol. 2012;107(10):1530.CrossRef
26.
go back to reference Li Y, Yang X, Xu C, Zhang Y, Zhang X. Normal values and pressure morphology for three-dimensional high-resolution anorectal manometry of asymptomatic adults: a study in 110 subjects. Int J Colorectal Dis. 2013;28(8):1161–8.CrossRef Li Y, Yang X, Xu C, Zhang Y, Zhang X. Normal values and pressure morphology for three-dimensional high-resolution anorectal manometry of asymptomatic adults: a study in 110 subjects. Int J Colorectal Dis. 2013;28(8):1161–8.CrossRef
27.
go back to reference Lee H, Jung K, Han S, Kim J, Park SK, Yoon I, et al. Normal values for high-resolution anorectal manometry/topography in a healthy Korean population and the effects of gender and body mass index. Neurogastroenterol Motil. 2014;26(4):529–37.CrossRef Lee H, Jung K, Han S, Kim J, Park SK, Yoon I, et al. Normal values for high-resolution anorectal manometry/topography in a healthy Korean population and the effects of gender and body mass index. Neurogastroenterol Motil. 2014;26(4):529–37.CrossRef
28.
go back to reference Coss-Adame E, Rao SS, Valestin J, Ali-Azamar A, Remes-Troche JM. Accuracy and reproducibility of high-definition anorectal manometry and pressure topography analyses in healthy subjects. Clin Gastroenterol Hepatol. 2015;13(6):1143–50.CrossRef Coss-Adame E, Rao SS, Valestin J, Ali-Azamar A, Remes-Troche JM. Accuracy and reproducibility of high-definition anorectal manometry and pressure topography analyses in healthy subjects. Clin Gastroenterol Hepatol. 2015;13(6):1143–50.CrossRef
29.
go back to reference Lee TH, Bharucha AE. How to perform and interpret a high-resolution anorectal manometry test. J Neurogastroenterol Motil. 2016;22(1):46–59.CrossRef Lee TH, Bharucha AE. How to perform and interpret a high-resolution anorectal manometry test. J Neurogastroenterol Motil. 2016;22(1):46–59.CrossRef
30.
go back to reference Azpiroz F, Enck P, Whitehead WE. Anorectal functional testing: review of collective experience. Am J Gastroenterol. 2002;97(2):232–40.PubMed Azpiroz F, Enck P, Whitehead WE. Anorectal functional testing: review of collective experience. Am J Gastroenterol. 2002;97(2):232–40.PubMed
31.
go back to reference Prichard D, Harvey DM, Fletcher JG, Zinsmeister AR, Bharucha AE. Relationship among anal sphincter injury, patulous anal canal, and anal pressures in patients with anorectal disorders. Clin Gastroenterol Hepatol. 2015;13(10):1793–800.CrossRef Prichard D, Harvey DM, Fletcher JG, Zinsmeister AR, Bharucha AE. Relationship among anal sphincter injury, patulous anal canal, and anal pressures in patients with anorectal disorders. Clin Gastroenterol Hepatol. 2015;13(10):1793–800.CrossRef
32.
go back to reference Leroi A-M, Berkelmans I, Denis P, Hémond M, Devroede G. Anismus as a marker of sexual abuse. Dig Dis Sci. 1995;40(7):1411–6.CrossRef Leroi A-M, Berkelmans I, Denis P, Hémond M, Devroede G. Anismus as a marker of sexual abuse. Dig Dis Sci. 1995;40(7):1411–6.CrossRef
Metadata
Title
Anorectal Functional Outcomes Following Doppler-Guided Transanal Hemorrhoidal Dearterialization: Evidence from Vietnam
Authors
Le Manh Cuong
Vu Nam
Tran Thai Ha
Tran Thu Ha
Tran Quang Hung
Do Van Loi
Tran Manh Hung
Nguyen Van Son
Vu Duy Kien
Publication date
01-03-2020
Publisher
Springer Healthcare
Keyword
Hemorrhoids
Published in
Advances in Therapy / Issue 3/2020
Print ISSN: 0741-238X
Electronic ISSN: 1865-8652
DOI
https://doi.org/10.1007/s12325-020-01238-9

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