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BMC Pediatrics

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01-12-2020 | Helicobacter Pylori | Case report

Ménétrier’s disease in childhood: a case report from China

Authors: Jiewei Zhang, Yizhong Wang, Haifeng Liu, Yongmei Xiao, Ting Zhang

Published in: BMC Pediatrics | Issue 1/2020

Abstract

Background

Ménétrier’s disease (MD) is a protein-losing gastropathy characterized by gastric hypertrophy, foveolar hyperplasia and hypoalbuminemia. MD is uncommon in childhood with nonspecific clinical symptoms, and the exact cause of pediatric MD is still unclear.

Case presentation

Here, we reported a 4 year and 10-month boy presenting with MD from China. The patient was suffered with vomiting, abdominal pain, hypoproteinemia and edema. Laboratory tests showed that the boy was infected with Clostridium difficile (CD). Gastrointestinal endoscopy revealed giant gastric folds, and histological gastric biopsies showed foveolar hyperplasia with glandular atrophy, infiltration of eosinophils in the lamina propria of the patient. Finally, the boy was recovered after supportive therapy with intravenous albumin and CD eradication.

Conclusion

For the nonspecific clinical symptoms of MD, gastrointestinal endoscopic evaluations with gastric tissue biopsies are required to establish the diagnosis of MD in children with unexplained hypoalbuminemia.

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Title: Ménétrier’s disease in childhood: a case report from China
Authors: Jiewei Zhang
Yizhong Wang
Haifeng Liu
Yongmei Xiao
Ting Zhang
Publication date: 01-12-2020
Publisher: BioMed Central
Keywords: Helicobacter Pylori
Edema
Vomiting
Supportive Care
Clostridioides Difficile
Upper and Lower Gastrointestinal Endoscopy
Key Symptom
Abdominal Pain
Published in: BMC Pediatrics / Issue 1/2020
Electronic ISSN: 1471-2431
DOI: https://doi.org/10.1186/s12887-020-2005-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Ménétrier’s disease in childhood: a case report from China

Abstract

Background

Case presentation

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusion

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