Skip to main content
Top
Published in: BMC Gastroenterology 1/2009

Open Access 01-12-2009 | Research article

Helicobacter pylori infection: approach of primary care physicians in a developing country

Authors: Shahid Ahmed, Mohammad Salih, Wasim Jafri, Hasnain Ali Shah, Saeed Hamid

Published in: BMC Gastroenterology | Issue 1/2009

Login to get access

Abstract

Background

The aim of the study was to assess the knowledge and practices of primary care physicians in diagnosis and management of Helicobacter pylori (H. pylori) infection in developing country.

Methods

This convenient sample based, cross sectional study was conducted in primary care physicians of Karachi, Pakistan from March 2008 to August 2008 through a pretested self-designed questionnaire, which contained 11 items pertaining to H. pylori route of transmission, diagnosis, indication for testing, treatment options, follow up and source of information.

Results

Out of 509 primary care physicians, 451 consented to participate with the response rate of 88.6%. Responses of 426 primary care physicians were analyzed after excluding 19 physicians. 78% of the physicians thought that contaminated water was the source of spread of infection, dyspepsia was the most frequent indication for investigating H. pylori infection (67% of the physicians), while 43% physicians were of the view that serology was the most appropriate test to diagnose active H. pylori infection. 77% of physicians thought that gastric ulcer was the most compelling indication for treatment, 61% physicians preferred Clarithromycin based triple therapy for 7–14 days. 57% of the physicians would confirm H. pylori eradication after treatment in selected patients and 47% physicians preferred serological testing for follow-up. In case of treatment failure, only 36% of the physicians were in favor of gastroenterologist referral.

Conclusion

The primary care physicians in this study lacked in knowledge regarding management of H. pylori infection. Internationally published guidelines and World gastroenterology organization (WGO) practice guideline on H. pylori for developing countries have little impact on current practices of primary care physicians. We recommend more teaching programs, continuous medical education activities regarding H. pylori infection.
Appendix
Available only for authorised users
Literature
1.
go back to reference Taylor DN, Blaser MJ: The epidemiology of Helicobacter pylori infection. Epidemiol Rev. 1991, 13: 42-59.PubMed Taylor DN, Blaser MJ: The epidemiology of Helicobacter pylori infection. Epidemiol Rev. 1991, 13: 42-59.PubMed
2.
go back to reference Parsonnet J: Helicobacter pylori. Infect Dis Clin North Am. 1998, 12 (1): 185-197. 10.1016/S0891-5520(05)70417-7.CrossRefPubMed Parsonnet J: Helicobacter pylori. Infect Dis Clin North Am. 1998, 12 (1): 185-197. 10.1016/S0891-5520(05)70417-7.CrossRefPubMed
3.
go back to reference Frenck RW, Clemens J: Helicobacter in developing world. Microbes Infect. 2003, 5: 705-713. 10.1016/S1286-4579(03)00112-6.CrossRefPubMed Frenck RW, Clemens J: Helicobacter in developing world. Microbes Infect. 2003, 5: 705-713. 10.1016/S1286-4579(03)00112-6.CrossRefPubMed
5.
go back to reference Huang JQ, Sridhar S, Hunt RH: Role of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic-ulcer disease: a meta-analysis. Lancet. 2002, 359: 14-22. 10.1016/S0140-6736(02)07273-2.CrossRefPubMed Huang JQ, Sridhar S, Hunt RH: Role of Helicobacter pylori infection and non-steroidal anti-inflammatory drugs in peptic-ulcer disease: a meta-analysis. Lancet. 2002, 359: 14-22. 10.1016/S0140-6736(02)07273-2.CrossRefPubMed
6.
go back to reference Marshall BJ: Helicobacter pylori. Am J Gastroenterol. 1994, 89: S116-128.PubMed Marshall BJ: Helicobacter pylori. Am J Gastroenterol. 1994, 89: S116-128.PubMed
7.
go back to reference Rauws EA, Tytgat GN: Cure of duodenal ulcer associated with eradication of Helicobacter pylori. Lancet. 1990, 335: 233-235. 10.1016/0140-6736(90)91301-P.CrossRef Rauws EA, Tytgat GN: Cure of duodenal ulcer associated with eradication of Helicobacter pylori. Lancet. 1990, 335: 233-235. 10.1016/0140-6736(90)91301-P.CrossRef
8.
go back to reference Graham DY, Lew GM, Klein PD, Evans DG, Evans DJ, Saeed ZA, Malaty HM: Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer. A randomized, controlled study. Ann Intern Med. 1992, 116: 705-708.CrossRefPubMed Graham DY, Lew GM, Klein PD, Evans DG, Evans DJ, Saeed ZA, Malaty HM: Effect of treatment of Helicobacter pylori infection on the long-term recurrence of gastric or duodenal ulcer. A randomized, controlled study. Ann Intern Med. 1992, 116: 705-708.CrossRefPubMed
9.
go back to reference Moayyedi P, Deeks J, Talley NJ: An update of the Cochrane systemic review of Helicobacter pylori eradication therapy in nonulcer dyspepsia: resolving the discrepancy between systemic reviews. Am J Gastroentrol. 2003, 98: 2621-2626. 10.1111/j.1572-0241.2003.08724.x.CrossRef Moayyedi P, Deeks J, Talley NJ: An update of the Cochrane systemic review of Helicobacter pylori eradication therapy in nonulcer dyspepsia: resolving the discrepancy between systemic reviews. Am J Gastroentrol. 2003, 98: 2621-2626. 10.1111/j.1572-0241.2003.08724.x.CrossRef
10.
go back to reference Huang J, Lam SK, Malfertheiner P, Hunt RH: Has education about Helicobacter pylori infection been effective? Worldwide survey of primary care physicians. J Gastroenterol Hepatol. 2003, 18: 512-520. 10.1046/j.1440-1746.2003.03017.x.CrossRefPubMed Huang J, Lam SK, Malfertheiner P, Hunt RH: Has education about Helicobacter pylori infection been effective? Worldwide survey of primary care physicians. J Gastroenterol Hepatol. 2003, 18: 512-520. 10.1046/j.1440-1746.2003.03017.x.CrossRefPubMed
11.
go back to reference NIH Consensus Conference. Helicobacter pylori in peptic ulcer disease. NIH Consensus Development Panel on Helicobacter pylori in Peptic Ulcer Disease. JAMA. 1994, 272: 65-69. 10.1001/jama.272.1.65. NIH Consensus Conference. Helicobacter pylori in peptic ulcer disease. NIH Consensus Development Panel on Helicobacter pylori in Peptic Ulcer Disease. JAMA. 1994, 272: 65-69. 10.1001/jama.272.1.65.
12.
go back to reference Weijnen CF, Numans ME, de Wit NJ, Smout AJ, Moons KG, Verheij TJ, Hoes AW: Testing for Helicobacter pylori in dyspeptic patients suspected of peptic ulcer disease in primary care: cross sectional study. BMJ. 2001, 323: 71-75. 10.1136/bmj.323.7304.71.CrossRefPubMedPubMedCentral Weijnen CF, Numans ME, de Wit NJ, Smout AJ, Moons KG, Verheij TJ, Hoes AW: Testing for Helicobacter pylori in dyspeptic patients suspected of peptic ulcer disease in primary care: cross sectional study. BMJ. 2001, 323: 71-75. 10.1136/bmj.323.7304.71.CrossRefPubMedPubMedCentral
13.
go back to reference Howden CW, Hunt RH: Guidelines for the management of Helicobacter pylori infection. Ad Hoc Committee on Practice Parameters of the American College of Gastroenterology. Am J Gastroenterol. 93: 2330-2338. 10.1111/j.1572-0241.1998.00684.x. Howden CW, Hunt RH: Guidelines for the management of Helicobacter pylori infection. Ad Hoc Committee on Practice Parameters of the American College of Gastroenterology. Am J Gastroenterol. 93: 2330-2338. 10.1111/j.1572-0241.1998.00684.x.
14.
go back to reference Howden CW: For what conditions is there evidence-based justification for treatment of Helicobacter pylori infection?. Gastroenterology. 1997, 113: S107-112. 10.1016/S0016-5085(97)70086-6.CrossRefPubMed Howden CW: For what conditions is there evidence-based justification for treatment of Helicobacter pylori infection?. Gastroenterology. 1997, 113: S107-112. 10.1016/S0016-5085(97)70086-6.CrossRefPubMed
16.
go back to reference Kim BG, Kim JM, Jeong JB, Jung YJ, Lee KL: Discrepancies between primary physician practice and treatment guidelines for Helicobacter pylori infection in Korea. World J Gastroenterol. 2006, 12 (1): 66-69.CrossRefPubMedPubMedCentral Kim BG, Kim JM, Jeong JB, Jung YJ, Lee KL: Discrepancies between primary physician practice and treatment guidelines for Helicobacter pylori infection in Korea. World J Gastroenterol. 2006, 12 (1): 66-69.CrossRefPubMedPubMedCentral
17.
go back to reference Canbaz S, Sunter AT, Peksen Y, Leblebicioglu H: Survey of general practitioners' knowledge about Helicobacter pylori infection. BMC Gastroenterol. 2005, 5: 4-10.1186/1471-230X-5-4.CrossRefPubMedPubMedCentral Canbaz S, Sunter AT, Peksen Y, Leblebicioglu H: Survey of general practitioners' knowledge about Helicobacter pylori infection. BMC Gastroenterol. 2005, 5: 4-10.1186/1471-230X-5-4.CrossRefPubMedPubMedCentral
18.
go back to reference Maconi G, Tosetti C, Miroglio G, Parente F, Colombo E, Sainaghi M, Bianchi Porro G: Management of Helicobacter Pylori-related gastrointestinal diseases by general practitioners in Italy. Aliment Pharmacol Ther. 1999, 13 (11): 1499-1504. 10.1046/j.1365-2036.1999.00648.x.CrossRefPubMed Maconi G, Tosetti C, Miroglio G, Parente F, Colombo E, Sainaghi M, Bianchi Porro G: Management of Helicobacter Pylori-related gastrointestinal diseases by general practitioners in Italy. Aliment Pharmacol Ther. 1999, 13 (11): 1499-1504. 10.1046/j.1365-2036.1999.00648.x.CrossRefPubMed
Metadata
Title
Helicobacter pylori infection: approach of primary care physicians in a developing country
Authors
Shahid Ahmed
Mohammad Salih
Wasim Jafri
Hasnain Ali Shah
Saeed Hamid
Publication date
01-12-2009
Publisher
BioMed Central
Published in
BMC Gastroenterology / Issue 1/2009
Electronic ISSN: 1471-230X
DOI
https://doi.org/10.1186/1471-230X-9-23

Other articles of this Issue 1/2009

BMC Gastroenterology 1/2009 Go to the issue
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.