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Published in: Infection 1/2014

01-02-2014 | Brief Report

Heavy alcohol use as a risk factor for severe outcomes among adults hospitalized with laboratory-confirmed influenza, 2005–2012

Authors: A. Greenbaum, S. S. Chaves, A. Perez, D. Aragon, A. Bandyopadhyay, N. Bennett, B. Fowler, E. Hancock, R. Lynfield, C. McDonald-Hamm, A. Reingold, P. Ryan, W. Schaffner, R. Sharangpani, M. Spencer, A. Thomas, K. Yousey-Hindes, S. Zansky, L. Finelli

Published in: Infection | Issue 1/2014

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Abstract

We examined heavy alcohol use as a risk factor for severe influenza (intensive care admission or death) among hospitalized adults. In <65- and ≥65-year-olds, heavy alcohol use increased disease severity [relative risk (RR) 1.34; 95 % confidence interval (CI): 1.04–1.74, and RR 2.47; 95 % CI: 1.69–3.60, respectively]. Influenza vaccination and early, empiric antiviral treatment should be emphasized in this population.
Footnotes
1
Persons at higher risk for influenza complications include persons aged ≥65 years; persons with chronic pulmonary (including asthma), cardiovascular (except hypertension alone), renal, hepatic, hematological (including sickle-cell disease), metabolic disorders (including diabetes mellitus), or neurological and neurodevelopment conditions (including disorders of the brain, spinal cord, peripheral nerve, and muscle, such as cerebral palsy, epilepsy, stroke, intellectual disability, moderate to severe developmental delay, muscular dystrophy, or spinal cord injury); and persons with immunosuppression, including that caused by medications or HIV infection. For a complete list, see “Prevention and control of influenza with vaccines: Recommendations of the Advisory Committee on Immunization Practices (ACIP), 2010” [5].
 
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Metadata
Title
Heavy alcohol use as a risk factor for severe outcomes among adults hospitalized with laboratory-confirmed influenza, 2005–2012
Authors
A. Greenbaum
S. S. Chaves
A. Perez
D. Aragon
A. Bandyopadhyay
N. Bennett
B. Fowler
E. Hancock
R. Lynfield
C. McDonald-Hamm
A. Reingold
P. Ryan
W. Schaffner
R. Sharangpani
M. Spencer
A. Thomas
K. Yousey-Hindes
S. Zansky
L. Finelli
Publication date
01-02-2014
Publisher
Springer Berlin Heidelberg
Published in
Infection / Issue 1/2014
Print ISSN: 0300-8126
Electronic ISSN: 1439-0973
DOI
https://doi.org/10.1007/s15010-013-0534-8

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