Skip to main content
Top
Published in: BMC Health Services Research 1/2005

Open Access 01-12-2005 | Research article

Heart failure guidelines and prescribing in primary care across Europe

Authors: Heidrun B Sturm, Wiek H van Gilst, Karl Swedberg, FD Richard Hobbs, Flora M Haaijer-Ruskamp

Published in: BMC Health Services Research | Issue 1/2005

Login to get access

Abstract

Background

Major international differences in heart failure treatment have been repeatedly described, but the reasons for these differences remain unclear. National guideline recommendations might be a relevant factor. This study, therefore, explored variation of heart failure guideline recommendations in Europe.

Methods

Treatment recommendations of 14 national guidelines published after 1994 were analyzed in relation to the heart failure treatment guideline of the European Society of Cardiology. To test potential relations between recommendations and prescribing, national prescribing patterns as obtained by a European study in primary care (IMPROVEMENT-HF) were related to selected recommendations in those countries.

Results

Besides the 14 national guidelines used by primary care physicians in the countries contacted, the European guideline was used in four countries, and separate guidelines for specialists and primary care were available in another four countries. Two countries indicated that no guideline was used up to 2000. Comprehensiveness of the guidelines varied with respect to length, literature included and evidence ratings. Relevant differences in treatment recommendations were seen only in drug classes where evidence had changed recently (β-blockers and spironolactone). The relation between recommendation and prescribing for selected recommendations was inconsistent among countries.

Conclusion

Differences in guideline recommendations are not sufficient to explain variation of prescribing among countries, thus other factors must be considered.
Appendix
Available only for authorised users
Literature
1.
go back to reference Cleland JG, Khand A, Clark A: The heart failure epidemic: exactly how big is it?. Eur Heart J. 2001, 22: 623-626. 10.1053/euhj.2000.2493.CrossRefPubMed Cleland JG, Khand A, Clark A: The heart failure epidemic: exactly how big is it?. Eur Heart J. 2001, 22: 623-626. 10.1053/euhj.2000.2493.CrossRefPubMed
2.
go back to reference Komajda M, Follath F, Swedberg K, Cleland J, Aguilar JC, Cohen-Solal A, Dietz R, Gavazzi A, van Gilst WH, Hobbs R, Korewicki J, Madeira HC, Moiseyev VS, Preda I, Widimsky J, Freemantle N, Eastaugh J, Mason J: The EuroHeart Failure Survey programme--a survey on the quality of care among patients with heart failure in Europe. Part 2: treatment. Eur Heart J. 2003, 24: 464-474. 10.1016/S0195-668X(02)00700-5.CrossRefPubMed Komajda M, Follath F, Swedberg K, Cleland J, Aguilar JC, Cohen-Solal A, Dietz R, Gavazzi A, van Gilst WH, Hobbs R, Korewicki J, Madeira HC, Moiseyev VS, Preda I, Widimsky J, Freemantle N, Eastaugh J, Mason J: The EuroHeart Failure Survey programme--a survey on the quality of care among patients with heart failure in Europe. Part 2: treatment. Eur Heart J. 2003, 24: 464-474. 10.1016/S0195-668X(02)00700-5.CrossRefPubMed
3.
go back to reference Cleland JG, Cohen-Solal A, Aguilar JC, Dietz R, Eastaugh J, Follath F, Freemantle N, Gavazzi A, van Gilst WH, Hobbs FD, Korewicki J, Madeira HC, Preda I, Swedberg K, Widimsky J: Management of heart failure in primary care (the IMPROVEMENT of Heart Failure Programme): an international survey. Lancet. 2002, 360: 1631-1639. 10.1016/S0140-6736(02)11601-1.CrossRefPubMed Cleland JG, Cohen-Solal A, Aguilar JC, Dietz R, Eastaugh J, Follath F, Freemantle N, Gavazzi A, van Gilst WH, Hobbs FD, Korewicki J, Madeira HC, Preda I, Swedberg K, Widimsky J: Management of heart failure in primary care (the IMPROVEMENT of Heart Failure Programme): an international survey. Lancet. 2002, 360: 1631-1639. 10.1016/S0140-6736(02)11601-1.CrossRefPubMed
4.
go back to reference Bellotti P, Badano LP, Acquarone N, Griffo R, Lo PG, Maggioni AP, Mattiauda C, Menardo G, Mombelloni P: Specialty-related differences in the epidemiology, clinical profile, management and outcome of patients hospitalized for heart failure; the OSCUR study. Oucome dello Scompenso Cardiaco in relazione all'Utilizzo delle Risore. Eur Heart J. 2001, 22: 596-604. 10.1053/euhj.2000.2362.CrossRefPubMed Bellotti P, Badano LP, Acquarone N, Griffo R, Lo PG, Maggioni AP, Mattiauda C, Menardo G, Mombelloni P: Specialty-related differences in the epidemiology, clinical profile, management and outcome of patients hospitalized for heart failure; the OSCUR study. Oucome dello Scompenso Cardiaco in relazione all'Utilizzo delle Risore. Eur Heart J. 2001, 22: 596-604. 10.1053/euhj.2000.2362.CrossRefPubMed
5.
go back to reference Grimshaw GM, Khunti K, Baker R: Diagnosis of heart failure in primary care: an assessment of international guidelines. Br J Gen Pract. 2001, 51: 384-386.PubMedPubMedCentral Grimshaw GM, Khunti K, Baker R: Diagnosis of heart failure in primary care: an assessment of international guidelines. Br J Gen Pract. 2001, 51: 384-386.PubMedPubMedCentral
6.
go back to reference Kulig M, Erika S, Norbert WS: Comparing methodological quality and consistency of international guidelines for the management of patients with chronic heart failure. Eur J Heart Fail. 2003, 5: 327-335. 10.1016/S1388-9842(03)00040-0.CrossRefPubMed Kulig M, Erika S, Norbert WS: Comparing methodological quality and consistency of international guidelines for the management of patients with chronic heart failure. Eur J Heart Fail. 2003, 5: 327-335. 10.1016/S1388-9842(03)00040-0.CrossRefPubMed
7.
go back to reference Burgers JS, Bailey JV, Klazinga NS, Van Der Bij AK, Grol R, Feder G: Inside guidelines: comparative analysis of recommendations and evidence in diabetes guidelines from 13 countries. Diabetes Care. 2002, 25: 1933-1939.CrossRefPubMed Burgers JS, Bailey JV, Klazinga NS, Van Der Bij AK, Grol R, Feder G: Inside guidelines: comparative analysis of recommendations and evidence in diabetes guidelines from 13 countries. Diabetes Care. 2002, 25: 1933-1939.CrossRefPubMed
8.
go back to reference Iqbal A, Schloss S, George D, Isonaka S: Worldwide guidelines for chronic obstructive pulmonary disease: A comparison of diagnosis and treatment recommendations. Respirology. 2002, 7: 233-239. 10.1046/j.1440-1843.2002.00399.x.CrossRefPubMed Iqbal A, Schloss S, George D, Isonaka S: Worldwide guidelines for chronic obstructive pulmonary disease: A comparison of diagnosis and treatment recommendations. Respirology. 2002, 7: 233-239. 10.1046/j.1440-1843.2002.00399.x.CrossRefPubMed
9.
go back to reference The treatment of heart failure. The Task Force on Heart Failure of the European Society of Cardiology. Eur Heart J. 1997, 18: 736-753. The treatment of heart failure. The Task Force on Heart Failure of the European Society of Cardiology. Eur Heart J. 1997, 18: 736-753.
10.
go back to reference Grilli R, Magrini N, Penna A, Mura G, Liberati A: Practice guidelines developed by specialty societies: the need for a critical appraisal. Lancet. 2000, 355: 103-106. 10.1016/S0140-6736(99)02171-6.CrossRefPubMed Grilli R, Magrini N, Penna A, Mura G, Liberati A: Practice guidelines developed by specialty societies: the need for a critical appraisal. Lancet. 2000, 355: 103-106. 10.1016/S0140-6736(99)02171-6.CrossRefPubMed
11.
go back to reference Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, Palensky J, Wittes J: The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med. 1999, 341: 709-717. 10.1056/NEJM199909023411001.CrossRefPubMed Pitt B, Zannad F, Remme WJ, Cody R, Castaigne A, Perez A, Palensky J, Wittes J: The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. N Engl J Med. 1999, 341: 709-717. 10.1056/NEJM199909023411001.CrossRefPubMed
12.
go back to reference A randomized trial of beta-blockade in heart failure. The Cardiac Insufficiency Bisoprolol Study (CIBIS). CIBIS Investigators and Committees. Circulation. 1994, 90: 1765-1773. A randomized trial of beta-blockade in heart failure. The Cardiac Insufficiency Bisoprolol Study (CIBIS). CIBIS Investigators and Committees. Circulation. 1994, 90: 1765-1773.
13.
go back to reference Burgers JS, Grol RPTM, Zaat JOM, Spies TH, Van Der Bij AK, Mokkink HGA: Characteristics of effective clinical guidelines for general practice. British Journal of General Practice. 2003, 53: 15-19.PubMedPubMedCentral Burgers JS, Grol RPTM, Zaat JOM, Spies TH, Van Der Bij AK, Mokkink HGA: Characteristics of effective clinical guidelines for general practice. British Journal of General Practice. 2003, 53: 15-19.PubMedPubMedCentral
14.
go back to reference Remme WJ: Towards the better treatment of heart failure. Eur Heart J. 1998, 19 Suppl L: L36-L42.PubMed Remme WJ: Towards the better treatment of heart failure. Eur Heart J. 1998, 19 Suppl L: L36-L42.PubMed
15.
go back to reference Cline CM, Boman K, Holst M, Erhardt LR, Failure fS SS: The management of heart failure in Sweden. Eur J Heart Fail. 2002, 4: 373-376.CrossRefPubMed Cline CM, Boman K, Holst M, Erhardt LR, Failure fS SS: The management of heart failure in Sweden. Eur J Heart Fail. 2002, 4: 373-376.CrossRefPubMed
16.
go back to reference Komajda M, Bouhour JB, Amouyel P, Delahaye F, Vicaut E, Croce I, Rougemond E, Vuittenez F, Leutenegger E: Ambulatory heart failure management in private practice in France. Eur J Heart Fail. 2001, 3: 503-507. 10.1016/S1388-9842(01)00172-6.CrossRefPubMed Komajda M, Bouhour JB, Amouyel P, Delahaye F, Vicaut E, Croce I, Rougemond E, Vuittenez F, Leutenegger E: Ambulatory heart failure management in private practice in France. Eur J Heart Fail. 2001, 3: 503-507. 10.1016/S1388-9842(01)00172-6.CrossRefPubMed
17.
go back to reference McKee SP, Leslie SJ, LeMaitre JP, Webb DJ, Denvir MA: Management of chronic heart failure due to systolic left ventricular dysfunction by cardiologist and non-cardiologist physicians. Eur J Heart Fail. 2003, 5: 549-555. 10.1016/S1388-9842(03)00003-5.CrossRefPubMed McKee SP, Leslie SJ, LeMaitre JP, Webb DJ, Denvir MA: Management of chronic heart failure due to systolic left ventricular dysfunction by cardiologist and non-cardiologist physicians. Eur J Heart Fail. 2003, 5: 549-555. 10.1016/S1388-9842(03)00003-5.CrossRefPubMed
18.
go back to reference Rutten FH, Grobbee DE, Hoes AW: Differences between general practitioners and cardiologists in diagnosis and management of heart failure: a survey in every-day practice. Eur J Heart Fail. 2003, 5: 337-344. 10.1016/S1388-9842(03)00050-3.CrossRefPubMed Rutten FH, Grobbee DE, Hoes AW: Differences between general practitioners and cardiologists in diagnosis and management of heart failure: a survey in every-day practice. Eur J Heart Fail. 2003, 5: 337-344. 10.1016/S1388-9842(03)00050-3.CrossRefPubMed
19.
go back to reference Fuat A, Hungin AP, Murphy JJ: Barriers to accurate diagnosis and effective management of heart failure in primary care: qualitative study. BMJ. 2003, 326: 196-10.1136/bmj.326.7382.196.CrossRefPubMedPubMedCentral Fuat A, Hungin AP, Murphy JJ: Barriers to accurate diagnosis and effective management of heart failure in primary care: qualitative study. BMJ. 2003, 326: 196-10.1136/bmj.326.7382.196.CrossRefPubMedPubMedCentral
20.
go back to reference Khunti K, Hearnshaw H, Baker R, Grimshaw G: Heart failure in primary care: qualitative study of current management and perceived obstacles to evidence-based diagnosis and management by general practitioners. Eur J Heart Fail. 2002, 4: 771-777. 10.1016/S1388-9842(02)00119-8.CrossRefPubMed Khunti K, Hearnshaw H, Baker R, Grimshaw G: Heart failure in primary care: qualitative study of current management and perceived obstacles to evidence-based diagnosis and management by general practitioners. Eur J Heart Fail. 2002, 4: 771-777. 10.1016/S1388-9842(02)00119-8.CrossRefPubMed
21.
go back to reference Cluzeau F, Burgers J, Brouwers M, Grol R, Makela M, Littlejohns P, Grimshaw J, Hunt C: Development and validation of an international appraisal instrument for assessing the quality of clinical practice guidelines: the AGREE project. Quality & Safety in Health Care. 2003, 12: 18-23. 10.1136/qhc.12.1.18.CrossRef Cluzeau F, Burgers J, Brouwers M, Grol R, Makela M, Littlejohns P, Grimshaw J, Hunt C: Development and validation of an international appraisal instrument for assessing the quality of clinical practice guidelines: the AGREE project. Quality & Safety in Health Care. 2003, 12: 18-23. 10.1136/qhc.12.1.18.CrossRef
22.
go back to reference Adams KF: Translating heart failure guidelines into clinical practice: clinical science and the art of medicine. Curr Cardiol Rep. 2001, 3: 130-135.CrossRefPubMed Adams KF: Translating heart failure guidelines into clinical practice: clinical science and the art of medicine. Curr Cardiol Rep. 2001, 3: 130-135.CrossRefPubMed
23.
go back to reference Wensing M, van der WT, Grol R: Implementing guidelines and innovations in general practice: which interventions are effective?. Br J Gen Pract. 1998, 48: 991-997.PubMedPubMedCentral Wensing M, van der WT, Grol R: Implementing guidelines and innovations in general practice: which interventions are effective?. Br J Gen Pract. 1998, 48: 991-997.PubMedPubMedCentral
24.
go back to reference van Veldhuisen DJ, Charlesworth A, Crijns HJ, Lie KI, Hampton JR: Differences in drug treatment of chronic heart failure between European countries. Eur Heart J. 1999, 20: 666-672. 10.1053/euhj.1998.1343.CrossRefPubMed van Veldhuisen DJ, Charlesworth A, Crijns HJ, Lie KI, Hampton JR: Differences in drug treatment of chronic heart failure between European countries. Eur Heart J. 1999, 20: 666-672. 10.1053/euhj.1998.1343.CrossRefPubMed
Metadata
Title
Heart failure guidelines and prescribing in primary care across Europe
Authors
Heidrun B Sturm
Wiek H van Gilst
Karl Swedberg
FD Richard Hobbs
Flora M Haaijer-Ruskamp
Publication date
01-12-2005
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2005
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/1472-6963-5-57

Other articles of this Issue 1/2005

BMC Health Services Research 1/2005 Go to the issue