Skip to main content
Top
Published in: BMC Health Services Research 1/2005

Open Access 01-12-2005 | Research article

Volume-based referral for cardiovascular procedures in the United States: a cross-sectional regression analysis

Authors: Andrew J Epstein, Saif S Rathore, Harlan M Krumholz, Kevin GM Volpp

Published in: BMC Health Services Research | Issue 1/2005

Login to get access

Abstract

Background

We sought to estimate the numbers of patients affected and deaths avoided by adopting the Leapfrog Group's recommended hospital procedure volume minimums for coronary artery bypass graft (CABG) surgery and percutaneous coronary intervention (PCI). In addition to hospital risk-adjusted mortality standards, the Leapfrog Group recommends annual hospital procedure minimums of 450 for CABG and 400 for PCI to reduce procedure-associated mortality.

Methods

We conducted a retrospective analysis of a national hospital discharge database to evaluate in-hospital mortality among patients who underwent PCI (n = 2,500,796) or CABG (n = 1,496,937) between 1998 and 2001. We calculated the number of patients treated at low volume hospitals and simulated the number of deaths potentially averted by moving all patients to high volume hospitals under best-case conditions (i.e., assuming the full volume-associated reduction in mortality and the capacity to move all patients to high volume hospitals with no related harms).

Results

Multivariate adjusted odds of in-hospital mortality were higher for patients treated in low volume hospitals compared with high volume hospitals for CABG (OR 1.16, 95% CI 1.10–1.24) and PCI (OR 1.12, 95% CI 1.05–1.20). A policy of hospital volume minimums would have required moving 143,687 patients for CABG and 87,661 patients for PCI from low volume to high volume hospitals annually and prevented an estimated 619 CABG deaths and 109 PCI deaths. Thus, preventing a single death would have required moving 232 CABG patients or 805 PCI patients from low volume to high volume hospitals.

Conclusion

Recommended hospital CABG and PCI volume minimums would prevent 728 deaths annually in the United States, fewer than previously estimated. It is unclear whether a policy requiring the movement of large numbers of patients to avoid relatively few deaths is feasible or effective.
Literature
1.
go back to reference Hannan EL, Kilburn HJ, Bernard H, O'Donnell JF, Lukacik G, Shields EP: Coronary artery bypass surgery: the relationship between inhospital mortality rate and surgical volume after controlling for clinical risk factors. Med Care. 1991, 29: 1094-1107.CrossRefPubMed Hannan EL, Kilburn HJ, Bernard H, O'Donnell JF, Lukacik G, Shields EP: Coronary artery bypass surgery: the relationship between inhospital mortality rate and surgical volume after controlling for clinical risk factors. Med Care. 1991, 29: 1094-1107.CrossRefPubMed
2.
go back to reference Hannan EL, Popp AJ, Tranmer B, Fuestel P, Waldman J, Shah D: Relationship between provider volume and mortality for carotid endarterectomies in New York state. Stroke. 1998, 29: 2292-2297.CrossRefPubMed Hannan EL, Popp AJ, Tranmer B, Fuestel P, Waldman J, Shah D: Relationship between provider volume and mortality for carotid endarterectomies in New York state. Stroke. 1998, 29: 2292-2297.CrossRefPubMed
3.
go back to reference Hannan EL, Racz M, Ryan TJ, McCallister BD, Johnson LW, Arani DT, Guerci AD, Sosa J, Topol EJ: Coronary angioplasty volume-outcome relationships for hospitals and cardiologists. JAMA. 1997, 277: 892-898. 10.1001/jama.277.11.892.CrossRefPubMed Hannan EL, Racz M, Ryan TJ, McCallister BD, Johnson LW, Arani DT, Guerci AD, Sosa J, Topol EJ: Coronary angioplasty volume-outcome relationships for hospitals and cardiologists. JAMA. 1997, 277: 892-898. 10.1001/jama.277.11.892.CrossRefPubMed
7.
go back to reference Birkmeyer JD, Dimick JB: Potential benefits of the new Leapfrog standards: effect of process and outcomes measures. Surgery. 2004, 135: 569-575. 10.1016/j.surg.2004.03.004.CrossRefPubMed Birkmeyer JD, Dimick JB: Potential benefits of the new Leapfrog standards: effect of process and outcomes measures. Surgery. 2004, 135: 569-575. 10.1016/j.surg.2004.03.004.CrossRefPubMed
8.
go back to reference Dudley RA, Johansen KL, Brand R, Rennie DJ, Milstein A: Selective referral to high-volume hospitals: estimating potentially avoidable deaths. JAMA. 2000, 283: 1159-1166. 10.1001/jama.283.9.1159.CrossRefPubMed Dudley RA, Johansen KL, Brand R, Rennie DJ, Milstein A: Selective referral to high-volume hospitals: estimating potentially avoidable deaths. JAMA. 2000, 283: 1159-1166. 10.1001/jama.283.9.1159.CrossRefPubMed
9.
go back to reference Birkmeyer JD, Finlayson EVA, Birkmeyer CM: Volume standards for high-risk surgical procedures: potential benefits of the Leapfrog initiative. Surgery. 2001, 130: 415-422. 10.1067/msy.2001.117139.CrossRefPubMed Birkmeyer JD, Finlayson EVA, Birkmeyer CM: Volume standards for high-risk surgical procedures: potential benefits of the Leapfrog initiative. Surgery. 2001, 130: 415-422. 10.1067/msy.2001.117139.CrossRefPubMed
10.
go back to reference Steiner C, Elixhauser A, Schnaier J: The Healthcare Cost and Utilization Project: an overview. Eff Clin Pract. 2002, 5: 143-151.PubMed Steiner C, Elixhauser A, Schnaier J: The Healthcare Cost and Utilization Project: an overview. Eff Clin Pract. 2002, 5: 143-151.PubMed
13.
go back to reference Birkmeyer JD, Stukel TA, Siewers AE, Goodney PP, Wennberg DE, Lucas FL: Surgeon volume and operative mortality in the United States. N Engl J Med. 2003, 349: 2117-2127. 10.1056/NEJMsa035205.CrossRefPubMed Birkmeyer JD, Stukel TA, Siewers AE, Goodney PP, Wennberg DE, Lucas FL: Surgeon volume and operative mortality in the United States. N Engl J Med. 2003, 349: 2117-2127. 10.1056/NEJMsa035205.CrossRefPubMed
14.
go back to reference Jollis JG, Peterson ED, DeLong ER, Mark DB, Collins SR, Muhlbaier LH, Pryor DB: The relation between the volume of coronary angioplasty procedures at hospitals treating Medicare beneficiaries and short-term mortality. N Engl J Med. 1994, 331: 1625-1629. 10.1056/NEJM199412153312406.CrossRefPubMed Jollis JG, Peterson ED, DeLong ER, Mark DB, Collins SR, Muhlbaier LH, Pryor DB: The relation between the volume of coronary angioplasty procedures at hospitals treating Medicare beneficiaries and short-term mortality. N Engl J Med. 1994, 331: 1625-1629. 10.1056/NEJM199412153312406.CrossRefPubMed
15.
go back to reference Jollis JG, Peterson ED, Nelson CL, Stafford JA, DeLong ER, Muhlbaier LH, Mark DB: Relationship between physician and hospital coronary angioplasty volume and outcome in elderly patients. Circulation. 1997, 95: 2485-2491.CrossRefPubMed Jollis JG, Peterson ED, Nelson CL, Stafford JA, DeLong ER, Muhlbaier LH, Mark DB: Relationship between physician and hospital coronary angioplasty volume and outcome in elderly patients. Circulation. 1997, 95: 2485-2491.CrossRefPubMed
17.
go back to reference Rathore SS, Epstein AJ, Volpp KGM, Krumholz HM: Hospital coronary artery bypass graft surgery volume and patient mortality, 1998-2000. Ann Surg. 2004, 239: 110-117. 10.1097/01.sla.0000103066.22732.b8.CrossRefPubMedPubMedCentral Rathore SS, Epstein AJ, Volpp KGM, Krumholz HM: Hospital coronary artery bypass graft surgery volume and patient mortality, 1998-2000. Ann Surg. 2004, 239: 110-117. 10.1097/01.sla.0000103066.22732.b8.CrossRefPubMedPubMedCentral
18.
go back to reference Epstein AJ, Rathore SS, Volpp KGM, Krumholz HM: Hospital percuatenous coronary intervention volume and patient mortality, 1998 to 2000: does the evidence support current procedure volume minimums?. J Am Coll Cardiol. 2004, 43: 1755-1762. 10.1016/j.jacc.2003.09.070.CrossRefPubMedPubMedCentral Epstein AJ, Rathore SS, Volpp KGM, Krumholz HM: Hospital percuatenous coronary intervention volume and patient mortality, 1998 to 2000: does the evidence support current procedure volume minimums?. J Am Coll Cardiol. 2004, 43: 1755-1762. 10.1016/j.jacc.2003.09.070.CrossRefPubMedPubMedCentral
19.
go back to reference Peterson ED, Coombs LP, DeLong ER, Haan CK, Ferguson TB: Procedural volume as a marker of quality for CABG surgery. JAMA. 2004, 291: 195-201. 10.1001/jama.291.2.195.CrossRefPubMed Peterson ED, Coombs LP, DeLong ER, Haan CK, Ferguson TB: Procedural volume as a marker of quality for CABG surgery. JAMA. 2004, 291: 195-201. 10.1001/jama.291.2.195.CrossRefPubMed
20.
go back to reference Petersen LA, Normand SL, Leape LL, McNeil BJ: Regionalization and the underuse of angiography in the Veterans Affairs health care system as compared with a fee-for-service system. N Engl J Med. 2003, 348: 2209-2217. 10.1056/NEJMsa021725.CrossRefPubMed Petersen LA, Normand SL, Leape LL, McNeil BJ: Regionalization and the underuse of angiography in the Veterans Affairs health care system as compared with a fee-for-service system. N Engl J Med. 2003, 348: 2209-2217. 10.1056/NEJMsa021725.CrossRefPubMed
21.
go back to reference Finlayson SRG, Birkmeyer CM, Tosteson ANA, Nease RFJ: Patient preferences for location of care: implications for regionalization. Med Care. 1999, 37: 204-209. 10.1097/00005650-199902000-00010.CrossRefPubMed Finlayson SRG, Birkmeyer CM, Tosteson ANA, Nease RFJ: Patient preferences for location of care: implications for regionalization. Med Care. 1999, 37: 204-209. 10.1097/00005650-199902000-00010.CrossRefPubMed
22.
go back to reference Shahian DM, Normand SLT: The volume-outcome relationship: from Luft to Leapfrog. Ann Thorac Surg. 2003, 75: 1048-1058. 10.1016/S0003-4975(02)04308-4.CrossRefPubMed Shahian DM, Normand SLT: The volume-outcome relationship: from Luft to Leapfrog. Ann Thorac Surg. 2003, 75: 1048-1058. 10.1016/S0003-4975(02)04308-4.CrossRefPubMed
23.
go back to reference Epstein AJ, Rathore SS: Coronary artery bypass surgery, hospital volume, and risk. Circulation. 2003, 108: e6-e7. 10.1161/01.CIR.0000079058.43607.8B.CrossRefPubMed Epstein AJ, Rathore SS: Coronary artery bypass surgery, hospital volume, and risk. Circulation. 2003, 108: e6-e7. 10.1161/01.CIR.0000079058.43607.8B.CrossRefPubMed
24.
go back to reference Jones RH, Hannan EL, Hammermeister KE, DeLong ER, O'Connor GT, Luepker RV, Parsonnet V, Pryor DB, for the Working Group Panel on the Cooperative CABG Database Project: Identification of preoperative variables needed for risk-adjustment of short-term mortality after coronary artery bypass graft surgery. J Am Coll Cardiol. 1996, 28: 1478-1487. 10.1016/S0735-1097(96)00359-2.CrossRefPubMed Jones RH, Hannan EL, Hammermeister KE, DeLong ER, O'Connor GT, Luepker RV, Parsonnet V, Pryor DB, for the Working Group Panel on the Cooperative CABG Database Project: Identification of preoperative variables needed for risk-adjustment of short-term mortality after coronary artery bypass graft surgery. J Am Coll Cardiol. 1996, 28: 1478-1487. 10.1016/S0735-1097(96)00359-2.CrossRefPubMed
25.
go back to reference Hannan EL, Wu C, Ryan TJ, Bennett E, Culliford AT, Gold JP, Hartman A, Isom OW, Jones RH, McNeil B, Rose EA, Subramanian VA: Do hospitals and surgeons with higher coronary artery bypass graft surgery volumes still have lower risk-adjusted mortality rates?. Circulation. 2003, 108: 795-801. 10.1161/01.CIR.0000084551.52010.3B.CrossRefPubMed Hannan EL, Wu C, Ryan TJ, Bennett E, Culliford AT, Gold JP, Hartman A, Isom OW, Jones RH, McNeil B, Rose EA, Subramanian VA: Do hospitals and surgeons with higher coronary artery bypass graft surgery volumes still have lower risk-adjusted mortality rates?. Circulation. 2003, 108: 795-801. 10.1161/01.CIR.0000084551.52010.3B.CrossRefPubMed
26.
go back to reference McGrath PD, Wennberg DE, Dickens JDJ, Siewers AE, Lucas FL, Malenka DJ, Kellett MAJ, Ryan TJJ: Relation between operator and hospital volume and outcomes following percutaneous coronary interventions in the era of the coronary stent. JAMA. 2000, 284: 3139-3144. 10.1001/jama.284.24.3139.CrossRefPubMed McGrath PD, Wennberg DE, Dickens JDJ, Siewers AE, Lucas FL, Malenka DJ, Kellett MAJ, Ryan TJJ: Relation between operator and hospital volume and outcomes following percutaneous coronary interventions in the era of the coronary stent. JAMA. 2000, 284: 3139-3144. 10.1001/jama.284.24.3139.CrossRefPubMed
Metadata
Title
Volume-based referral for cardiovascular procedures in the United States: a cross-sectional regression analysis
Authors
Andrew J Epstein
Saif S Rathore
Harlan M Krumholz
Kevin GM Volpp
Publication date
01-12-2005
Publisher
BioMed Central
Published in
BMC Health Services Research / Issue 1/2005
Electronic ISSN: 1472-6963
DOI
https://doi.org/10.1186/1472-6963-5-42

Other articles of this Issue 1/2005

BMC Health Services Research 1/2005 Go to the issue