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Published in: International Journal of Clinical Pharmacy 4/2018

01-08-2018 | Research Article

Healthcare professionals’ knowledge, attitude and practice towards adverse drug reaction (ADR) reporting at the health center level in Ethiopia

Authors: Mohammed Assen Seid, Asmamaw Emagn Kasahun, Bamlak Markos Mante, Saron Naji Gebremariam

Published in: International Journal of Clinical Pharmacy | Issue 4/2018

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Abstract

Background Adverse drug reactions (ADRs) are major health problems which are of global concern. Spontaneous reporting of adverse drug reactions constitutes a crucial contribution to patient care. Objective The purpose of this study was to assess the knowledge, attitudes, and practices of healthcare professionals towards adverse drug reaction reporting. Setting Health care professionals in Gondar, Ethiopia. Methods A cross-sectional study was conducted from March to May 2017. Data were collected through self-administered questionnaires. The collected data were analyzed using SPSS version 20. Binary logistic regression analysis was performed to distinguish factors that affect adverse drug reaction reporting. A p value < 0.05 was considered as a statistically significant. Main outcome measure Factors affecting adverse drug reaction reporting of health care professionals. Results Of 102 healthcare professionals included in this study, 61 (59. 8%) were nurses, 16 (15.7%) health officers, and 25 (24.5%) pharmacy professionals. Nearly 48 (47%) study participants had an inadequate level of knowledge towards adverse drug reaction reporting. The majority of participants 88 (86.3%) had a positive attitude, while more than half (51%) of study participants did not report the adverse drug reaction they encountered. Participants who had not taken adverse drug reaction reporting training (p = 0.037), health officers (p = 0.019), and nurse professionals (p = 0.001) showed a statistically significant association with an inadequate level of knowledge. Conclusion Even though the majority of healthcare professionals had a positive attitude, they had an inadequate level of knowledge and practice towards adverse drug reaction reporting.
Literature
1.
go back to reference World Health Organization. “International drug monitoring: the role of national centers”, Technical Report Series 498. Geneva: World Health Organization; 1972. World Health Organization. “International drug monitoring: the role of national centers”, Technical Report Series 498. Geneva: World Health Organization; 1972.
2.
go back to reference Schatz S, Weber R. Adverse drug reactions. Pharm Pract. 2015;1:1. Schatz S, Weber R. Adverse drug reactions. Pharm Pract. 2015;1:1.
3.
go back to reference Edwards IR, Aronson JK. Adverse drug reactions: definitions, diagnosis, and management. Lancet. 2000;356:1255–9.CrossRef Edwards IR, Aronson JK. Adverse drug reactions: definitions, diagnosis, and management. Lancet. 2000;356:1255–9.CrossRef
4.
go back to reference Iffat W, Shakeel S, Rahim N, Anjum F, Nesar S, Ghayas S. Pakistani physicians knowledge and attitude towards reporting adverse drug reactions. Afr J Pharm Pharmacol. 2014;8:379–85. Iffat W, Shakeel S, Rahim N, Anjum F, Nesar S, Ghayas S. Pakistani physicians knowledge and attitude towards reporting adverse drug reactions. Afr J Pharm Pharmacol. 2014;8:379–85.
5.
go back to reference Ganesan S, Vikneswaran G, Reddy KC, Subrahmanyam D, Adithan C. A survey on knowledge, attitude and practice of pharmacovigilance towards adverse drug reactions reporting among doctors and Nurses in a Tertiary Care Hospital in South India. J Young Pharm. 2016;8. Ganesan S, Vikneswaran G, Reddy KC, Subrahmanyam D, Adithan C. A survey on knowledge, attitude and practice of pharmacovigilance towards adverse drug reactions reporting among doctors and Nurses in a Tertiary Care Hospital in South India. J Young Pharm. 2016;8.
6.
go back to reference Adimasu A. Nurses knowledge related to adverse drug reaction reporting and associated factors at Felegehiwot Referral Hospital and University of Gondar Teaching Hospital, Northwest Ethiopia. Am J Health Res. 2014;2:164–70.CrossRef Adimasu A. Nurses knowledge related to adverse drug reaction reporting and associated factors at Felegehiwot Referral Hospital and University of Gondar Teaching Hospital, Northwest Ethiopia. Am J Health Res. 2014;2:164–70.CrossRef
7.
go back to reference Davies EC, Green CF, Taylor S, Williamson PR, Mottram DR, Pirmohamed M. Adverse drug reactions in hospital in-patients: a prospective analysis of 3695 patient-episodes. PLoS ONE. 2009;4:e4439.CrossRef Davies EC, Green CF, Taylor S, Williamson PR, Mottram DR, Pirmohamed M. Adverse drug reactions in hospital in-patients: a prospective analysis of 3695 patient-episodes. PLoS ONE. 2009;4:e4439.CrossRef
9.
go back to reference Bule MH, Hamido BA, Sileshi T. Knowledge, attitudes and practices of healthcare professionals towards adverse drug reaction reporting in Adama hospital medical college, east Shoa zone, Oromia regional state, Ethiopia. Pharma Innov J. 2016;18:17. Bule MH, Hamido BA, Sileshi T. Knowledge, attitudes and practices of healthcare professionals towards adverse drug reaction reporting in Adama hospital medical college, east Shoa zone, Oromia regional state, Ethiopia. Pharma Innov J. 2016;18:17.
10.
go back to reference Shepherd G, Mohorn P, Yacoub K, May DW. Adverse drug reaction deaths reported in United States vital statistics, 1999–2006. Ann Pharmacother. 2012;46:169–75.CrossRef Shepherd G, Mohorn P, Yacoub K, May DW. Adverse drug reaction deaths reported in United States vital statistics, 1999–2006. Ann Pharmacother. 2012;46:169–75.CrossRef
11.
go back to reference Angamo MT, Chalmers L, Curtain CM, Bereznicki LR. Adverse-drug-reaction-related hospitalisations in developed and developing countries: a review of prevalence and contributing factors. Drug Saf. 2016;39:847–57.CrossRef Angamo MT, Chalmers L, Curtain CM, Bereznicki LR. Adverse-drug-reaction-related hospitalisations in developed and developing countries: a review of prevalence and contributing factors. Drug Saf. 2016;39:847–57.CrossRef
12.
go back to reference Vora M, Barvaliya M. Knowledge, attitude and practices towards pharmacovigilance and adverse drug reactions in health care professional of Tertiary Care Hospital, Bhavnagar. Int J Pharma Sci Res (IJPSR). 2014;5:820–6. Vora M, Barvaliya M. Knowledge, attitude and practices towards pharmacovigilance and adverse drug reactions in health care professional of Tertiary Care Hospital, Bhavnagar. Int J Pharma Sci Res (IJPSR). 2014;5:820–6.
14.
go back to reference Mulatu WN, Worku A. Assessment of knowledge, attitude and practice of health professionals towards adverse drug reaction reporting and factors associated with reporting. J Pharmacovigil. 2014;2:4. Mulatu WN, Worku A. Assessment of knowledge, attitude and practice of health professionals towards adverse drug reaction reporting and factors associated with reporting. J Pharmacovigil. 2014;2:4.
15.
go back to reference Goshime A. Assessment of knowledge, attitude and practices on adverse drug reaction reporting among pharmacy personnel working at Community Pharmacy. Addis Ababa: Addis Ababa University; 2015. Goshime A. Assessment of knowledge, attitude and practices on adverse drug reaction reporting among pharmacy personnel working at Community Pharmacy. Addis Ababa: Addis Ababa University; 2015.
16.
go back to reference Denekew A. Knowledge, attitude and practice of adverse drug reaction reporting and affecting factors among health care providers working in ART clinics of public health facilities in Addis Ababa city. Addis Ababa: School of Public Health, Addis Ababa University; 2014. Denekew A. Knowledge, attitude and practice of adverse drug reaction reporting and affecting factors among health care providers working in ART clinics of public health facilities in Addis Ababa city. Addis Ababa: School of Public Health, Addis Ababa University; 2014.
18.
go back to reference Pirmohamed M, James S, Meakin S, Green C, Scott AK, Walley TJ, et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18,820 patients. BMJ. 2004;329:15–9.CrossRef Pirmohamed M, James S, Meakin S, Green C, Scott AK, Walley TJ, et al. Adverse drug reactions as cause of admission to hospital: prospective analysis of 18,820 patients. BMJ. 2004;329:15–9.CrossRef
19.
go back to reference Oscanoa T, Lizaraso F, Carvajal A. Hospital admissions due to adverse drug reactions in the elderly. a meta-analysis. Eur J Clin Pharmacol. 2017;73:759–70.CrossRef Oscanoa T, Lizaraso F, Carvajal A. Hospital admissions due to adverse drug reactions in the elderly. a meta-analysis. Eur J Clin Pharmacol. 2017;73:759–70.CrossRef
20.
go back to reference Angamo MT, Curtain CM, Chalmers L, Yilma D, Bereznicki L. Predictors of adverse drug reaction-related hospitalization in Southwest Ethiopia: a prospective cross-sectional study. PLoS ONE. 2017;12:e0186631.CrossRef Angamo MT, Curtain CM, Chalmers L, Yilma D, Bereznicki L. Predictors of adverse drug reaction-related hospitalization in Southwest Ethiopia: a prospective cross-sectional study. PLoS ONE. 2017;12:e0186631.CrossRef
21.
go back to reference Carandang RR, Cao K, Jose NB, Almonte FD, Tinio RM. Research article knowledge and attitudes on adverse drug reaction reporting of selected hospital-based health practitioners in Manila, Philippines. Sch Acad J Pharm (SAJP). 2015;4:301–7. Carandang RR, Cao K, Jose NB, Almonte FD, Tinio RM. Research article knowledge and attitudes on adverse drug reaction reporting of selected hospital-based health practitioners in Manila, Philippines. Sch Acad J Pharm (SAJP). 2015;4:301–7.
22.
go back to reference Katekhaye VM, Kadhe NG, John J, Pawar SR. Knowledge, attitude and practice of pharmacovigilance among medical professionals at a tertiary care hospital in Mumbai, Maharashtra, India. Int J Res Med Sci. 2016;5:156–61.CrossRef Katekhaye VM, Kadhe NG, John J, Pawar SR. Knowledge, attitude and practice of pharmacovigilance among medical professionals at a tertiary care hospital in Mumbai, Maharashtra, India. Int J Res Med Sci. 2016;5:156–61.CrossRef
23.
go back to reference Drug Administration and Control Authority in collaboration with MSH/RPM plus/SPS Report on the assessment of health care providers’ knowledge, attitude and practice on Adverse Drug Reaction (ADR) reporting and its monitoring. Drug Administration and Control Authority, Addis Ababa, Ethiopia 2008. Drug Administration and Control Authority in collaboration with MSH/RPM plus/SPS Report on the assessment of health care providers’ knowledge, attitude and practice on Adverse Drug Reaction (ADR) reporting and its monitoring. Drug Administration and Control Authority, Addis Ababa, Ethiopia 2008.
24.
go back to reference Osakwe A, Oreagba I, Adewunmi AJ, Adekoya A, Fajolu I. Impact of training on Nigerian healthcare professionals’ knowledge and practice of pharmacovigilance. Int J Risk Saf Med. 2013;25(4):219–27.CrossRef Osakwe A, Oreagba I, Adewunmi AJ, Adekoya A, Fajolu I. Impact of training on Nigerian healthcare professionals’ knowledge and practice of pharmacovigilance. Int J Risk Saf Med. 2013;25(4):219–27.CrossRef
Metadata
Title
Healthcare professionals’ knowledge, attitude and practice towards adverse drug reaction (ADR) reporting at the health center level in Ethiopia
Authors
Mohammed Assen Seid
Asmamaw Emagn Kasahun
Bamlak Markos Mante
Saron Naji Gebremariam
Publication date
01-08-2018
Publisher
Springer International Publishing
Published in
International Journal of Clinical Pharmacy / Issue 4/2018
Print ISSN: 2210-7703
Electronic ISSN: 2210-7711
DOI
https://doi.org/10.1007/s11096-018-0682-0

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