Published in:
01-08-2013 | Secondary Headache (K Henry, Section Editor)
Headache and Epilepsy
Authors:
P. R. Bauer, J. A. Carpay, G. M. Terwindt, J. W. Sander, R. J. Thijs, J. Haan, G. H. Visser
Published in:
Current Pain and Headache Reports
|
Issue 8/2013
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Abstract
Headache and epilepsy often co-occur. Epidemiologic studies conducted in the past few years reinforce the notion of a bi-directional association between migraine and epilepsy. Data on an association between headache (in general) and epilepsy, however, are less clear. Peri-ictal headache often presents with migraine-like symptoms and can be severe. A correct diagnosis and management are paramount. It was demonstrated that cortical hyperexcitability may underlie both epilepsy and migraine. A recent study linked spreading depolarisation, the supposed underlying pathophysiological mechanism of migraine with aura, to epilepsy. Although this study was carried out in patients who had suffered a subarachnoid haemorrhage, the finding may shed light on pathophysiological mechanisms common to epilepsy and migraine.