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General Thoracic and Cardiovascular Surgery Cases

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Open Access 01-12-2023 | Hamartoma | Case Report

Mesenchymal cystic hamartoma of the lung mimicking simple pulmonary aspergilloma: a case report

Authors: Machiko Nishii-Mitsuaki, Chiaki Nakazono, Satoru Okada, Kenji Kameyama, Yoji Urata, Masayoshi Inoue, Yasuo Ueshima

Published in: General Thoracic and Cardiovascular Surgery Cases | Issue 1/2023

Abstract

Background

Mesenchymal cystic hamartoma is a rare pulmonary neoplasm, which occasionally presents with severe symptoms such as pneumothorax or hemothorax, and shows favorable outcomes following surgical resection. It presents as solitary or multiple cystic lesions and requires differentiation from cystic malignancies, lymphangiomyomatosis, and cystic adenomatoid malformation.

Case presentation

We encountered a 46-year-old woman with mesenchymal cystic hamartoma mimicking simple pulmonary aspergilloma on diagnostic imaging. Chest computed tomography showed a cystic lesion 1.6 cm in diameter, with an intracavitary nodule. Surgical resection proved neither fungus nor malignancy, and the final pathological diagnosis of mesenchymal cystic hamartoma was made.

Conclusions

Mesenchymal cystic hamartoma might show aspergilloma-like features on diagnostic imaging, in addition to the differential diagnosis of lung cancer.

Mark EJ. Mesenchymal cystic hamartoma of the lung. N Engl J Med. 1986;315(20):1255–9.CrossRefPubMed

Zhu H, Huang S, Zhou X. Mesenchymal cystic hamartoma of the lung. Ann Thorac Surg. 2012;93(6):e145–7.CrossRefPubMed

Yuan L, Wang S, Wei J, Yang K, Mao Y. Mesenchymal cystic hamartoma of the lung. Medicine. 2022;101(1):e28242.CrossRefPubMedPubMedCentral

Denning DW, Cadranel J, Beigelman-Aubry C, Ader F, Chakrabarti A, Blot S, et al. Chronic pulmonary aspergillosis: rationale and clinical guidelines for diagnosis and management. Eur Respir J. 2016;47(1):45–68.CrossRefPubMed

Leopizzi M, Cerbelli B, Merenda E, Pignataro MG, Bassi M, Venuta F, et al. Mesenchymal cystic hamartoma presenting with pneumothorax: case report and review of the literature. Gen Thorac Cardiovasc Surg. 2020;68:1573–8.CrossRefPubMed

Mennink-Kersten MASH, Donnelly JP, Verweij PE. Detection of circulating galactomannan for the diagnosis and management of invasive aspergillosis. Lancet Infect Dis. 2004;4(6):349–57.CrossRefPubMed

Chadwick SL, Corrin B, Hansell DM, Geddes DM. Fatal haemorrhage from mesenchymal cystic hamartoma of the lung. Eur Respir J. 1995;8(12):2182–4.CrossRefPubMed

Hedlund GL, Bisset GS, Bove KE. Malignant neoplasms arising in cystic hamartomas of the lung in childhood. Radiology. 1989;173(1):77–9.CrossRefPubMed

Bove KE. Sarcoma arising in pulmonary mesenchymal cystic hamartoma. Pediatr Pathol. 1989;9(6):785–92.CrossRefPubMed

Title: Mesenchymal cystic hamartoma of the lung mimicking simple pulmonary aspergilloma: a case report
Authors: Machiko Nishii-Mitsuaki
Chiaki Nakazono
Satoru Okada
Kenji Kameyama
Yoji Urata
Masayoshi Inoue
Yasuo Ueshima
Publication date: 01-12-2023
Publisher: BioMed Central
Keywords: Hamartoma
Computed Tomography
Computed Tomography
Hemothorax
Lung Cancer
Lung Cancer
Lung Cancer
Published in: General Thoracic and Cardiovascular Surgery Cases / Issue 1/2023
Electronic ISSN: 2731-6203
DOI: https://doi.org/10.1186/s44215-023-00047-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Mesenchymal cystic hamartoma of the lung mimicking simple pulmonary aspergilloma: a case report

Abstract

Background

Case presentation

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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