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31-01-2024 | Haloperidol | Editorial

How does haloperidol influence the long-term outcomes of delirium?

Authors: John W. Devlin, Matthew S. Duprey, Timothy D. Girard

Published in: Intensive Care Medicine | Issue 2/2024

Excerpt

Delirium, a complex acute confusional state that affects one-third to half of intensive care unit (ICU) patients, is associated with numerous adverse outcomes, including longer hospital stays, prolonged symptom burden, and increased risk for persistent cognitive impairment [1]. Recent studies that accounted for daily severity of illness [2] and hospital readmissions [3] found no significant relationship between delirium in the ICU and subsequent 1-year mortality, but early studies suggested delirium during critical illness may increase the long-term risk of death [4, 5]. Additionally, randomized trials have shown that the acute management of ICU patients can impact long-term survival [6], an outcome of great importance to patients and their families. Thus, clinicians remain very interested in the possibility that treatment of delirium acutely can improve long-term outcomes. …

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Duprey MS, Devlin JW, van der Hoeven JG, Pickkers P, Briesacher BA, Saczynski JS, Griffith JL, van den Boogaard M (2021) Association between incident delirium treatment with haloperidol and mortality in critically ill adults. Crit Care Med 49(8):1303–1311CrossRefPubMedPubMedCentral

Title: How does haloperidol influence the long-term outcomes of delirium?
Authors: John W. Devlin
Matthew S. Duprey
Timothy D. Girard
Publication date: 31-01-2024
Publisher: Springer Berlin Heidelberg
Keywords: Haloperidol
Post-Intensive Care Syndrome
Published in: Intensive Care Medicine / Issue 2/2024
Print ISSN: 0342-4642
Electronic ISSN: 1432-1238
DOI: https://doi.org/10.1007/s00134-024-07321-x

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How does haloperidol influence the long-term outcomes of delirium?

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