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European Radiology

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01-10-2013 | Neuro

Haemodynamic alterations in cerebral blood vessels after carotid artery revascularisation: quantitative analysis using 2D phase-contrast MRI

Authors: Sung Won Youn, Ho Kyun Kim, Young Rok Do, Jin Kook Do, Oh Choon Kwon, Nahee Lee, Hui Joong Lee, Jongmin Lee

Published in: European Radiology | Issue 10/2013

Abstract

Objectives

This study was conducted to evaluate the effect of revascularisation, whether revascularisation improves total cerebral blood flow volume (_FVTCBF), and how cerebral veins would respond to altered _FVTCBF.

Methods

The 39 carotid artery stenoses in 37 patients who underwent revascularisation including 32 stentings and 7 endarterectomies were included in this prospective study. From the two-dimensional phase-contrast (2D-PC) MRI acquired before and after revascularisation, the flow volumes (FVs) of the arteries and veins were compared using paired t-test. The relationships between these parameters were correlated using Pearson’s correlation coefficient.

Results

The mean FV in the treated carotid artery (proportion of treated artery among total FV) increased from 162.06 ml/min (25.80 %) to 267.71 ml/min (37.21 %; P < 0.001). Revascularisation increased the _FVTCBF of patients from 638.66 ml/min to 716.72 ml/min (P < 0.001). The FV of the internal jugular veins, superior sagittal and straight sinuses (_FVSS + SSS), and transverse sinuses increased after revascularisation (P < 0.05). Positive relationships were shown between the _FVTCBF and the _FVSS + SSS (r = 0.584–0.741, P < 0.001).

Conclusions

Revascularisation improves the _FVTCBF by increasing the FV in the treated carotid artery. The venous drainages are closely linked to _FVTCBF. 2D-PC-MRI is a feasible method for evaluating comprehensively the haemodynamic improvement after revascularisation.

Key Points

• Revascularisation may be beneficial in ischaemic strokes due to carotid artery stenosis.

• Revascularisation of the affected artery increases total cerebral blood flow volume (_FV TCBF).

• Cerebral venous drainage, closely linked to _FV TCBF, is also improved.

• Two-dimensional phase-contrast MRI can comprehensively assess these haemodynamic improvements after carotid revascularisation.

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Title: Haemodynamic alterations in cerebral blood vessels after carotid artery revascularisation: quantitative analysis using 2D phase-contrast MRI
Authors: Sung Won Youn
Ho Kyun Kim
Young Rok Do
Jin Kook Do
Oh Choon Kwon
Nahee Lee
Hui Joong Lee
Jongmin Lee
Publication date: 01-10-2013
Publisher: Springer Berlin Heidelberg
Published in: European Radiology / Issue 10/2013
Print ISSN: 0938-7994
Electronic ISSN: 1432-1084
DOI: https://doi.org/10.1007/s00330-013-2899-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Haemodynamic alterations in cerebral blood vessels after carotid artery revascularisation: quantitative analysis using 2D phase-contrast MRI

Abstract

Objectives

Methods

Results

Conclusions

Key Points

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

Key Points

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