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BMC Infectious Diseases
Published in: BMC Infectious Diseases 1/2018

Open Access 01-12-2018 | Case report

Guillain-Barre syndrome caused by hepatitis E infection: case report and literature review

Authors: Xiaoqin Zheng, Liang Yu, Qiaomai Xu, Silan Gu, Lingling Tang

Published in: BMC Infectious Diseases | Issue 1/2018

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Abstract

Background

Hepatitis E infection is a global disorder that causes substantial morbidity. Numerous neurologic illnesses, including Guillain–Barre syndrome (GBS), have occurred in patients with hepatitis E virus (HEV) infection.

Case presentation

We report a 58 year-old non-immunocompromised man who presented with progressive muscle weakness in all extremities during an episode of acute HEV infection, which was confirmed by measuring the anti-HEV IgM antibodies in the serum. Both cerebrospinal fluid examination and electrophysiological study were in agreement with the diagnosis of HEV-associated GBS. Following the treatment with intravenous immunoglobulin, the patient’s neurological condition improved rapidly.

Conclusions

HEV infection should be strongly considered in patients with neurological symptoms, especially those with elevated levels of liver enzymes.
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Metadata
Title
Guillain-Barre syndrome caused by hepatitis E infection: case report and literature review
Authors
Xiaoqin Zheng
Liang Yu
Qiaomai Xu
Silan Gu
Lingling Tang
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2018
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-018-2959-2

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