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01-03-2022 | Guillain-Barré Syndrome | COVID-19

Autoimmune encephalitis following ChAdOx1-S SARS-CoV-2 vaccination

Authors: Hyeryung Kwon, Taewon Kim

Published in: Neurological Sciences | Issue 3/2022

Excerpt

ChAdOx1-S (Covishield™/Vaxzevria, Astra-Zeneca) is the main vaccine recommended for mass national immunization program in the Republic of Korea against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and has been administered since March 2021. In addition to mild side effects including pain at the injection site, myalgia, arthralgia, and headache, a serious adverse effect involving vaccine-induced thrombotic thrombocytopenia (VITT) with vascular complications has been reported after administration of this adenovector-based SARS-CoV-2 vaccine [1, 2]. Rarely, autoimmune disease such as Guillain-Barré syndrome (GBS) has also been associated with ChAdOx1-S vaccination [3, 4]. However, as a post-vaccination phenomenon, autoimmune encephalitis (AE) has yet to be reported in the literature. Herein, we describe a patient who developed autoimmune encephalitis the day after the second dose of ChAdOx1-S vaccination with progressive cognitive worsening in a 4-week period. …

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Title: Autoimmune encephalitis following ChAdOx1-S SARS-CoV-2 vaccination
Authors: Hyeryung Kwon
Taewon Kim
Publication date: 01-03-2022
Publisher: Springer International Publishing
Keywords: Guillain-Barré Syndrome
Magnetic Resonance Imaging
Magnetic Resonance Imaging
Vaccination
SARS-CoV-2
Autoimmune Encephalitis
Published in: Neurological Sciences / Issue 3/2022
Print ISSN: 1590-1874
Electronic ISSN: 1590-3478
DOI: https://doi.org/10.1007/s10072-021-05790-2

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Autoimmune encephalitis following ChAdOx1-S SARS-CoV-2 vaccination

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