Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
ADVANCED SEARCH
Log in
Top
Journal of Thrombosis and Thrombolysis
Published in: Journal of Thrombosis and Thrombolysis 1/2016

Open Access 01-01-2016

Guidance for the use of thrombolytic therapy for the treatment of venous thromboembolism

Authors: Suresh Vedantham, Gregory Piazza, Akhilesh K. Sista, Neil A. Goldenberg

Published in: Journal of Thrombosis and Thrombolysis | Issue 1/2016

Login to get access

Abstract

Patients with venous thromboembolism (VTE) are prone to the development of both short-term and long-term complications that can substantially affect their functional capacity and quality of life. Patients with deep vein thrombosis (DVT) often develop recurrent VTE or the post-thrombotic syndrome, whereas patients with pulmonary embolism (PE) can develop long-term symptoms and functional limitations along a broad spectrum extending to full-blown chronic thromboembolic pulmonary hypertension. Clinicians who care for patients showing severe clinical manifestations of DVT and PE are often faced with challenging decisions concerning whether and how to escalate to more aggressive treatments such as those involving the use of thrombolytic drugs. The purpose of this chapter is to provide guidance on how best to individualize care to these patients.
Literature
1.
Huang W, Goldberg RJ, Anderson FA, Kiefe CI, Spence FA (2014) Secular trends in occurrence of acute venous thromboembolism: the Worcester VTE Study (1985–2009). Am J Med 127(9):829–839:e5PubMedPubMedCentralCrossRef
2.
Raffini L, Huang YS, Witmer C, Feudtner D (2009) Dramatic increase in venous thromboembolism in children’s hospitals in the United States from 2001 to 2007. Pediatrics 124(4):1001–1008PubMedCrossRef
3.
4.
Casazza F, Becattini C, Bongarzoni A, Cuccia C, Roncon L, Favretto G, Zonzin P, Pignataro L, Agnelli G (2012) Clinical features and short term outcomes of patients with acute pulmonary embolism. The italian pulmonary embolism registry (iper). Thromb Res 130:847–852PubMedCrossRef
5.
Becattini C, Casazza F, Forgione C, Porro F, Fadin BM, Stucchi A, Lignani A, Conte L, Imperadore F, Bongarzoni A, Agnelli G (2013) Acute pulmonary embolism: external validation of an integrated risk stratification model. Chest 144:1539–1545PubMedCrossRef
6.
Prandoni P, Noventa F, Ghirarduzzi A, Pengo V, Bernardi E, Pesavento R et al (2007) The risk of recurrent venous thromboembolism after discontinuing anticoagulation in patients with acute proximal deep vein thrombosis or pulmonary embolism. A prospective cohort study in 1626 patients. Haematologica 92:199–205PubMedCrossRef
7.
Sogaard KK, Schmidt M, Pedersen L, Horvath-Puho E, Sorensen HT (2014) 30-year mortality after venous thromboembolism: a population-based cohort study. Circulation 130:829–836PubMedCrossRef
8.
Kahn SR, Shrier I, Julian JA et al (2008) Determinants and time course of the postthrombotic syndrome after acute deep venous thrombosis. Ann Intern Med 149:698–707PubMedCrossRef
9.
Kahn SR, Comerota AJ, Cushman M, Evans NS, Ginsberg JS, Goldenberg NA, Gupta DK, Prandoni P, Vedantham S, Walsh E, Weitz JI (2014) The post-thrombotic syndrome: evidence-based prevention, diagnosis, and treatment strategies—a scientific statement from the American Heart Association. Circulation 130:1636–1661PubMedCrossRef
10.
Goldenberg NA, Donadini MP, Kahn SR, Crowther M, Kenet G, Nowak-Gottl U, Manco-Johnson MJ (2010) Post-thrombotic syndrome in children: a systematic review of frequency of occurrence, validity of outcome measures, and prognostic factors. Haematologica 95(11):1952–1959PubMedPubMedCentralCrossRef
11.
Piazza G, Goldhaber SZ (2011) Chronic thromboembolic pulmonary hypertension. N Engl J Med 364:351–360PubMedCrossRef
12.
Becattini C, Agnelli G, Salvi A, Grifoni S, Pancaldi LG, Enea I, Balsemin F, Campanini M, Ghirarduzzi A, Casazza F (2010) Bolus tenecteplase for right ventricle dysfunction in hemodynamically stable patients with pulmonary embolism. Thromb Res 125:e82–e86PubMedCrossRef
13.
Goldhaber SZ, Haire WD, Feldstein ML, Miller M, Toltzis R, Smith JL, Taveira da Silva AM, Come PC, Lee RT, Parker JA et al (1993) Alteplase versus heparin in acute pulmonary embolism: randomised trial assessing right-ventricular function and pulmonary perfusion. Lancet 341:507–511PubMedCrossRef
14.
Nass N, McConnell MV, Goldhaber SZ, Chyu S, Solomon SD (1999) Recovery of regional right ventricular function after thrombolysis for pulmonary embolism. Am J Cardiol 83(804–806):A810
15.
Sharma GV, Burleson VA, Sasahara AA (1980) Effect of thrombolytic therapy on pulmonary-capillary blood volume in patients with pulmonary embolism. N Engl J Med 303:842–845PubMedCrossRef
16.
Jerjes-Sanchez C, Ramirez-Rivera A, de Garcia ML, Arriaga-Nava R, Valencia S, Rosado-Buzzo A, Pierzo JA, Rosas E (1995) Streptokinase and heparin versus heparin alone in massive pulmonary embolism: a randomized controlled trial. J Thromb Thrombolysis 2:227–229PubMedCrossRef
17.
Chatterjee S, Chakraborty A, Weinberg I, Kadakia M, Wilensky RL, Sardar P, Kumbhani DJ, Mukherjee D, Jaff MR, Giri J (2014) Thrombolysis for pulmonary embolism and risk of all-cause mortality, major bleeding, and intracranial hemorrhage: a meta-analysis. JAMA 311:2414–2421PubMedCrossRef
18.
Kline JA, Steuerwald MT, Marchick MR, Hernandez-Nino J, Rose GA (2009) Prospective evaluation of right ventricular function and functional status 6 months after acute submassive pulmonary embolism: frequency of persistent or subsequent elevation in estimated pulmonary artery pressure. Chest 136:1202–1210PubMedPubMedCentralCrossRef
19.
Sharifi M, Bay C, Skrocki L, Rahimi F, Mehdipour M, Investigators M (2013) Moderate pulmonary embolism treated with thrombolysis (from the “mopett” trial). Am J Cardiol 111:273–277PubMedCrossRef
20.
Sharma GV, Folland ED, McIntyre KM, Sasahara AA (2000) Long-term benefit of thrombolytic therapy in patients with pulmonary embolism. Vasc Med 5:91–95PubMedCrossRef
21.
Kline JA, Nordenholz KE, Courtney DM, Kabrhel C, Jones AE, Rondina MT, Diercks DB, Klinger JR, Hernandez J (2014) Treatment of submassive pulmonary embolism with tenecteplase or placebo: cardiopulmonary outcomes at 3 months: Multicenter double-blind, placebo-controlled randomized trial. J Thromb Haemost 12:459–468PubMedCrossRef
22.
Mewissen WM, Seabrook GR, Meissner MH, Cynamon J, Labropoulos N, Haughton SH (1999) Catheter-directed thrombolysis for lower extremity deep venous thrombosis: report of a national multicenter registry. Radiology 211:39–49PubMedCrossRef
23.
Haig Y, Enden T, Slagsvold C et al (2013) Determinants of early and long-term efficacy of catheter-directed thrombolysis in proximal deep vein thrombosis. J Vasc Interv Radiol 24(1):17–24PubMedCrossRef
24.
Patel NH, Plorde JJ, Meissner M (1998) Catheter-directed thrombolysis in the treatment of phlegmasia cerulea dolens. Ann Vasc Surg 12(5):471–475PubMedCrossRef
25.
Vedantham S, Sista AK, Klein SJ, Nayak L, Razavi MK, Kalva SP, Saad WE, Dariushnia S, Caplin DM, Chao C, Ganguli S, Walker TG, Nikolic B, For the Society of Interventional Radiology and Cardiovascular and Interventional Radiological Society of Europe Standards of Practice Committees (2014) Quality improvement guidelines for the treatment of lower-extremity deep vein thrombosis with use of endovascular thrombus removal. J Vasc Interv Radiol 25:1317–1325PubMedCrossRef
26.
Elsharawy M, Elzayat E (2002) Early results of thrombolysis vs anticoagulation in iliofemoral venous thrombosis. A randomised clinical trial. Eur J Vasc Endovasc Surg 24:209–214PubMedCrossRef
27.
Kahn SR, Shbaklo H, Lamping DL et al (2008) Determinants of health-related quality of life during the 2 years following deep vein thrombosis. J Thromb Haemost 6:1105–1112PubMedCrossRef
28.
Guanella R, Ducruet T, Johri M, Miron MJ, Roussin A, Desmarais S, Joyal F, Kassis J, Solymoss S, Ginsberg JS, Lamping DL, Shrier I, Kahn SR (2011) Economic burden and cost determinants of deep vein thrombosis during 2 years following diagnosis: a prospective evaluation. J Thromb Haemost 9(12):2397–2405PubMedCrossRef
29.
30.
Jaff MR, McMurtry MS, Archer SL, Cushman M, Goldenberg N, Goldhaber SZ, Jenkins JS, Kline JA, Michaels AD, Thistlethwaite P, Vedantham S, White RJ, Zierler BK (2011) Management of massive and submassive pulmonary embolism, iliofemoral deep vein thrombosis, and chronic thromboembolic pulmonary hypertension: a scientific statement from the american heart association. Circulation 123:1788–1830PubMedCrossRef
31.
32.
33.
34.
Kearon C, Akl EA, Comerota AJ, Prandoni P, Bounameaux H, Goldhaber SZ, Nelson ME, Wells PS, Gould MK, Dentali F, Crowther M, Kahn SR (2012) Antithrombotic therapy for VTE disease: antithrombotic therapy and prevention of thrombosis, 9th ed: American college of chest physicians evidence-based clinical practice guidelines. Chest 141:e419S–e494SPubMedPubMedCentralCrossRef
35.
Stein PD, Matta F, Janjua M, Yaekoub AY, Jaweesh F, Alrifai A (2010) Outcome in stable patients with acute pulmonary embolism who had right ventricular enlargement and/or elevated levels of troponin i. Am J Cardiol 106:558–563PubMedCrossRef
36.
Schoepf UJ, Kucher N, Kipfmueller F, Quiroz R, Costello P, Goldhaber SZ (2004) Right ventricular enlargement on chest computed tomography: a predictor of early death in acute pulmonary embolism. Circulation 110:3276–3280PubMedCrossRef
37.
van der Meer RW, Pattynama PM, van Strijen MJ, van den Berg-Huijsmans AA, Hartmann IJ, Putter H, de Roos A, Huisman MV (2005) Right ventricular dysfunction and pulmonary obstruction index at helical CT: prediction of clinical outcome during 3-month follow-up in patients with acute pulmonary embolism. Radiology 235:798–803PubMedCrossRef
38.
Piazza G, Goldhaber SZ (2005) The acutely decompensated right ventricle: pathways for diagnosis and management. Chest 128:1836–1852PubMedCrossRef
39.
McConnell MV, Solomon SD, Rayan ME, Come PC, Goldhaber SZ, Lee RT (1996) Regional right ventricular dysfunction detected by echocardiography in acute pulmonary embolism. Am J Cardiol 78:469–473PubMedCrossRef
40.
Douketis JD, Crowther MA, Foster GA, Ginsberg JS (2001) Does the location of thrombosis determine the risk of disease recurrence in patients with proximal deep vein thrombosis? Am J Med 110(7):515–519PubMedCrossRef
41.
Delis KT, Bountouroglou D, Mansfield AO (2004) Venous claudication in iliofemoral thrombosis: long-term effects on venous hemodynamics, clinical status, and quality of life. Ann Surg 239(1):118–126PubMedPubMedCentralCrossRef
42.
Ginsberg JS, Hirsh J, Julian J, Vander LaandeVries M, Magier D, MacKinnon B, Gent M (2001) Prevention and treatment of postphlebitic syndrome: results of a 3-part study. Arch Intern Med 161:2105–2109PubMedCrossRef
43.
Meyer G, Vicaut E, Danays T, For the PEITHO Investigators et al (2014) Fibrinolysis for patients with intermediate-risk pulmonary embolism. N Engl J Med 370:1402–1411PubMedCrossRef
44.
Nakamura S, Takano H, Kubota Y, Asai K, Shimizu W (2014) Impact of the efficacy of thrombolytic therapy on the mortality of patients with acute submassive pulmonary embolism: a meta-analysis. J Thromb Haemost 12(7):1086–1095PubMedCrossRef
45.
46.
Wan S, Quinlan DJ, Agnelli G, Eikelboom JW (2004) Thrombolysis compared with heparin for the initial treatment of pulmonary embolism: a meta-analysis of the randomized controlled trials. Circulation 110:744–749PubMedCrossRef
47.
Goldhaber SZ, Buring JE, Lipnick RJ, Hennekens CH (1984) Pooled analyses of randomized trials of streptokinase and heparin in phlebographically documented acute deep venous thrombosis. Am J Med 76:393–397PubMedCrossRef
48.
Vedantham S, Grassi CJ, Ferral H, Patel NH, Thorpe PE, Antonacci VP, Janne D’Othee BM, Hofmann LV, Cardella JF, Kundu S, Lewis CA, Schwartzberg MS, Min RJ, Sacks D (2006) Reporting standards for endovascular treatment of lower extremity deep vein thrombosis. J Vasc Interv Radiol 17:417–434PubMedCrossRef
49.
Kuo WT, Gould MK, Louie JD, Rosenberg JK, Sze DY, Hofmann LV (2009) Catheter-directed therapy for the treatment of massive pulmonary embolism: systematic review and meta-analysis of modern techniques. J Vasc Interv Radiol 20:1431–1440PubMedCrossRef
50.
Goldhaber SZ (2007) Percutaneous mechanical thrombectomy for acute pulmonary embolism: a double-edged sword. Chest 132:363–365PubMedCrossRef
51.
Goldhaber SZ (2007) Percutaneous mechanical thrombectomy for massive pulmonary embolism: improve safety and efficacy by sharing information. Catheter Cardiovasc Interv 70:807–808PubMedCrossRef
52.
53.
Kearon C, Akl EA, Comerota AJ, Prandoni P, Bounameaux H, Goldhaber SZ, Nelson ME, Wells PS, Gould MK, Dentali F, Crowther M, Kahn SR (2012) Antithrombotic therapy for VTE disease: antithrombotic therapy and prevention of thrombosis, 9th ed.: American College of Chest Physicians evidence-based clinical practice guidelines. Chest 141:e419S–e494SPubMedPubMedCentralCrossRef
54.
Kucher N, Boekstegers P, Muller O, Kupatt C, Beyer-Westendorf J, Heitzer T, Tebbe U, Horstkotte J, Muller R, Blessing E, Greif M, Lange P, Hoffmann RT, Werth S, Barmeyer A, Hartel D, Grunwald H, Empen K, Baumgartner I (2014) Randomized controlled trial of ultrasound-assisted catheter-directed thrombolysis for acute intermediate-risk pulmonary embolism. Circulation 129:479–486PubMedCrossRef
55.
Piazza G, Hohlfelder B, Jaff MR, Ouriel K, Engelhardt TC, Sterling KM, Jones NJ, Gurley JC, Bhatheja R, Kennedy RJ, Goswami N, Natarajan K, Rundback J, Sadiq IR, Liu SK, Bhalla N, Raja ML, Weinstock BS, Cynamon J, Elmasri FF, Garcia MJ, Kumar M, Ayerdi J, Soukas P, Kuo W, Liu P, Goldhaber SZ (2014) A prospective, single-arm, multicenter trial of ultrasound-facilitated catheter-directed low-dose fibrinolysis for acute massive and submassive pulmonary embolism (seattle ii) Presented on March 30, 2014 at the American College of Cardiology Annual Scientific Sessions, Washington, D.C
56.
Semba CP, Dake MD (1994) Iliofemoral deep venous thrombosis: aggressive therapy with catheter-directed thrombolysis. Radiology 191:487–494PubMedCrossRef
57.
Enden T, Haig Y, Klow N et al (2012) Long-term outcomes after additional catheter-directed thrombolysis versus standard treatment for acute iliofemoral deep vein thrombosis (the CaVenT study): a randomised controlled trial. Lancet 379(9810):31–38PubMedCrossRef
58.
Kasirajan K, Gray B, Ouriel K (2001) Percutaneous Angiojet thrombectomy in the management of extensive deep venous thrombosis. J Vasc Interv Radiol 12:179–185PubMedCrossRef
59.
Vedantham S, Vesely TM, Parti N, Darcy M, Hovsepian DM, Picus D (2002) Lower extremity venous thrombolysis with adjunctive mechanical thrombectomy. J Vasc Interv Radiol 13(10):1001–1008PubMedCrossRef
60.
Uflacker R (1997) Mechanical thrombectomy in acute and subacute thrombosis with use of the Amplatz device: arterial and venous applications. J Vasc Interv Radiol 8:923–932PubMedCrossRef
61.
Delomez M, Beregi J, Willoteaux S, Bauchart JJ, d’Othee BJ, Asseman P et al (2001) Mechanical thrombectomy in patients with deep venous thrombosis. Cardiovasc Interv Radiol 24:42–48CrossRef
62.
Vedantham S, Vesely TM, Sicard GA et al (2004) Pharmacomechanical thrombolysis and early stent placement for iliofemoral deep vein thrombosis. J Vasc Interv Radiol 15:565–574PubMedCrossRef
63.
Bush RL, Lin PH, Bates JT, Mureebe L, Zhou W, Lumsden AB (2004) Pharmacomechanical thrombectomy for treatment of symptomatic lower extremity deep venous thrombosis: safety and feasibility study. J Vasc Surg 40:965–970PubMedCrossRef
64.
Lin PH, Zhou W, Dardik A, Mussa F, Kougias P, Hedayati N et al (2006) Catheter-direct thrombolysis versus pharmacomechanical thrombectomy for treatment of symptomatic lower extremity deep venous thrombosis. Am J Surg 192(6):782–788PubMedCrossRef
65.
Kim HS, Patra A, Paxton BE, Khan J, Streiff MB (2006) Adjunctive percutaneous mechanical thrombectomy for lower-extremity deep vein thrombosis: clinical and economic outcomes. J Vasc Interv Radiol 17:1099–1104PubMedCrossRef
66.
Cynamon J, Stein EG, Dym J, Jagust M, Binkert CA, Baum RA (2006) A new method for aggressive management of deep vein thrombosis: retrospective study of the power pulse technique. J Vasc Interv Radiol 17:1043–1049PubMedCrossRef
67.
O’Sullivan G, Lohan DG, Gough N, Cronin CG, Kee ST (2007) Pharmacomechanical thrombectomy of acute deep vein thrombosis with the Trellis-8 isolated thrombolysis catheter. J Vasc Interv Radiol 18(6):715–724PubMedCrossRef
68.
Vedantham S, Goldhaber SZ, Kahn SR, Julian J, Magnuson E, Jaff MR, Murphy TP, Cohen DJ, Comerota AJ, Gornik HL, Razavi MK, Lewis L, Kearon C (2013) Rationale and design of the Attract Study: a multicenter randomized trial to evaluate pharmacomechanical catheter-directed thrombolysis for the prevention of postthrombotic syndrome in patients with proximal deep vein thrombosis. Am Heart J 165(4):523–553PubMedPubMedCentralCrossRef
69.
Goldenberg NA, Branchford B, Wang M, Ray C Jr, Durham JD, Manco-Johnson MJ (2011) Percutaneous mechanical and pharmacomechanical thrombolysis for occlusive deep vein thrombosis of the proximal limb in adolescent subjects: findings from an institution-based prospective inception cohort study of pediatric venous thromboembolism. J Vasc Interv Radiol 22(2):121–132PubMedPubMedCentralCrossRef
70.
Baker R, Samuels S, Benenati JF et al (2012) Ultrasound-accelerated vs standard catheter-directed thrombolysis—a comparative study in patients with iliofemoral deep vein thrombosis. J Vasc Interv Radiol 23:1460–1466PubMedCrossRef
71.
Kucher N, Rossi E, De Rosa M, Goldhaber SZ (2006) Massive pulmonary embolism. Circulation 113(4):577–582PubMedCrossRef
72.
Stein PD, Matta F, Keyes DC, Willyerd GL (2012) Impact of vena cava filters on in-hospital case fatality rate from pulmonary embolism. Am J Med 125:478–484PubMedCrossRef
73.
Stein PD, Alnas M, Beemath A, Patel NR (2007) Outcome of pulmonary embolectomy. Am J Cardiol 99:421–423PubMedCrossRef
74.
Stein PD, Matta F (2012) Case fatality rate with pulmonary embolectomy for acute pulmonary embolism. Am J Med 125:471–477PubMedCrossRef
75.
Meneveau N, Seronde MF, Blonde MC et al (2006) Management of unsuccessful thrombolysis in acute massive pulmonary embolism. Chest 129:1043–1050PubMedCrossRef
76.
Leacche M, Unic D, Goldhaber SZ et al (2005) Modern surgical treatment of massive pulmonary embolism: results in 47 consecutive patients after rapid diagnosis and aggressive surgical approach. J Thorac Cardiovasc Surg 129(5):1018–1023PubMedCrossRef
77.
Sista A, Friedman OA, Horowitz JM, Salemi A (2013) Building a pulmonary embolism lysis practice. Endovasc Today 12:61–64
78.
Klok FA, van Kralingen KW, van Dijk AP et al (2010) Quality of life in long-term survivors of acute pulmonary embolism. Chest 138:1432–1440PubMedCrossRef
79.
Stevinson BG, Hernandez-Nino J, Rose G, Kline JA (2007) Echocardiographic and functional cardiopulmonary problems 6 months after first-time pulmonary embolism in previously healthy patients. Eur Heart J 28:2517–2524PubMedCrossRef
80.
Klok FA, Cohn DM, Middledorp S, Scharloo M, Buller HR, van Kralingen KW, Kaptein AA, Huisman MV (2010) Quality of life after pulmonary embolism: validation of the PEmb-QoL Questionnaire. J Thromb Haemost 8(3):523–532PubMedCrossRef
Metadata
Title
Guidance for the use of thrombolytic therapy for the treatment of venous thromboembolism
Authors
Suresh Vedantham
Gregory Piazza
Akhilesh K. Sista
Neil A. Goldenberg
Publication date
01-01-2016
Publisher
Springer US
Published in
Journal of Thrombosis and Thrombolysis / Issue 1/2016
Print ISSN: 0929-5305
Electronic ISSN: 1573-742X
DOI
https://doi.org/10.1007/s11239-015-1318-z

Other articles of this Issue 1/2016

Journal of Thrombosis and Thrombolysis 1/2016 Go to the issue

OriginalPaper

Guidance for the prevention and treatment of cancer-associated venous thromboembolism

OriginalPaper

Guidance for the treatment and prevention of obstetric-associated venous thromboembolism

OriginalPaper

Guidance for the management of venous thrombosis in unusual sites

OriginalPaper

Guidance for the evaluation and treatment of hereditary and acquired thrombophilia

OriginalPaper

Guidance for the practical management of warfarin therapy in the treatment of venous thromboembolism

OriginalPaper

Guidance for the prevention and treatment of the post-thrombotic syndrome
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits