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Hepatology International
Published in: Hepatology International 2/2014

01-09-2014 | Supplement Issue: ALPD

Growth factors enhance liver regeneration in acute-on-chronic liver failure

Authors: Chandan Kumar Kedarisetty, Lovkesh Anand, Arshi Khanam, Anupam Kumar, Archana Rastogi, Rakhi Maiwall, Shiv Kumar Sarin

Published in: Hepatology International | Special Issue 2/2014

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Abstract

Acute-on-chronic liver failure is a distinct syndrome characterized by a rapid progression of liver disease culminating in organ failure and death. The only definitive treatment is liver transplantation. However, there is a possible element of reversibility and hepatic regeneration if the acute insult can be tided over. Exogenously administered growth factors may stimulate hepatocytes, hepatic progenitor cells and bone marrow-derived cells to supplement hepatic regeneration. The proposed review is intended to provide an in-depth analysis of the individual components of hepatic and bone marrow niches and highlight the growing role of various growth factors in liver regeneration in health and in liver failure.
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Metadata
Title
Growth factors enhance liver regeneration in acute-on-chronic liver failure
Authors
Chandan Kumar Kedarisetty
Lovkesh Anand
Arshi Khanam
Anupam Kumar
Archana Rastogi
Rakhi Maiwall
Shiv Kumar Sarin
Publication date
01-09-2014
Publisher
Springer India
Published in
Hepatology International / Issue Special Issue 2/2014
Print ISSN: 1936-0533
Electronic ISSN: 1936-0541
DOI
https://doi.org/10.1007/s12072-014-9538-4

Other articles of this Special Issue 2/2014

Hepatology International 2/2014 Go to the issue

Supplement Issue: ALPD

Mechanisms of alcohol-induced hepatocellular carcinoma

Supplement Issue: ALPD

Liver transplantation for alcoholic hepatitis. Current situation and future

Supplement Issue: ALPD

Basis of HBV persistence and new treatment options

Erratum

Erratum to: Epigenetic histone modifications in a clinically relevant rat model of chronic ethanol-binge-mediated liver injury

Supplement Issue: ALPD

Alcohol, TLR4-TGF-β antagonism, and liver cancer

Supplement Issue: ALPD

Recent insights into hepatic cancer stem cells
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Obesity Clinical Trial Summary

At a glance: The STEP trials

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A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

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Year in Review: Valvular heart disease

Valvular Heart Disease Video

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Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

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ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

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New intervention for STEMI-related cardiogenic shock

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» View more highlights on the ACC 2024 congress hub page

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