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Chinese Medicine
Published in: Chinese Medicine 1/2020

01-12-2020 | Gout | Review

Chinese herbal medicine for gout: a review of the clinical evidence and pharmacological mechanisms

Authors: Xiansu Chi, Hongxiu Zhang, Shuo Zhang, Ke Ma

Published in: Chinese Medicine | Issue 1/2020

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Abstract

Gout is a common arthritis condition due to disorders of purine metabolism and decreased uric acid excretion. Although researchers have carried out various studies on this disease, there are no effective drugs for patients with gout. In traditional Chinese medicine (TCM), gout pertains the category of Bi pattern due to qi stagnation in the meridians and collaterals. Chinese herbal medicinals has been employed to treat Bi patterns since the ancient China. In recent decades, classical TCM formulas and agents isolated from some Chinese herbal medicinals have been applied to treat gout and have achieved satisfactory effect. In this review, we focus on recent studies of gout in which TCM formulas were applied to treat animal models or to treat patients, and summarize the mechanism of gout from TCM perspective, the clinical application, pharmacological mechanism and the chemical compounds of TCM formulas in treating gout. In conclusion, through this study, we summarized the application principle of TCM formulas in gout treatment and some key issues of current research, and we hope this study will provide some references for applying TCM formulas to treat gout and will lay a foundation for the development of novel formulas for gout treatments.
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Metadata
Title
Chinese herbal medicine for gout: a review of the clinical evidence and pharmacological mechanisms
Authors
Xiansu Chi
Hongxiu Zhang
Shuo Zhang
Ke Ma
Publication date
01-12-2020
Publisher
BioMed Central
Keyword
Gout
Published in
Chinese Medicine / Issue 1/2020
Electronic ISSN: 1749-8546
DOI
https://doi.org/10.1186/s13020-020-0297-y

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