Skip to main content
Key Specialties
Cardiology Diabetology Endocrinology Gastroenterology Geriatrics and Gerontology Gynecology and Obstetrics Hematology Infectious Disease Internal Medicine Nephrology Neurology Oncology Pediatrics Respiratory Medicine Rheumatology Surgery
Congress Coverage
2024 ACC Congress 2023 ESMO Congress 2023 EASD Congress 2023 ERS Congress 2023 ESC Congress
Clinical Collections
Advances in Alzheimer’s

Keynote webinar | Spotlight on medication adherence

LIVE: Thursday 27th June 2024, 18:00-19:30 (CEST)
Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.
ADVANCED SEARCH
Log in
Top
Endocrine
Published in: Endocrine 2/2020

01-05-2020 | Goiter | Original Article

Inherited thyroid tumours

Author: Dillwyn Williams

Published in: Endocrine | Issue 2/2020

Login to get access

Abstract

Inherited thyroid tumours are an important group which need clarification. This is partly because of the common use of the term Familial Non-Medullary Thyroid Cancer when some of the specific entities included under this heading really represent inherited benign tumours with a risk of progression to malignancy. The subject is briefly reviewed, and one syndromic and one non-syndromic type of inherited thyroid tumours of follicular cell origin discussed in more detail to emphasise the point that each of these groups need to be treated as separate entities.
Literature
1.
E.D. Williams, C.L. Brown, I. Doniach, Pathological and clinical findings in a series of 67 cases of medullary carcinoma of the thyroid. J. Clin. Path. 19, 103–113 (1966)CrossRef
2.
E.D. Williams, Histogenesis of medullary carcinoma of the thyroid. J. Clin. Path. 19, 114–118 (1966)CrossRef
3.
Y.S. Peiling, J. Ngeow, Familial non-medullary thyroid cancer: unravelling the genetic maze. Endocr. Relat. Cancer 23, R577–R595 (2016)CrossRef
4.
5.
L. Curtis, A.H. Wyllie, J.J. Shaw et al. Evidence against involvement of APC mutation in papillary thyroid cancer. Eur. J. Cancer 30A, 984–987 (1994)CrossRef
6.
H.R. Harach, G.T. Williams, E.D. Williams, Familial adenomatous polyposis associated thyroid carcinoma: a distinct type of follicular cell neoplasm. Histopathology 25, 549–561 (1994)CrossRef
7.
M. Miyaki, T. Iijima, R. Ishii et al. Molecular evidence for multicentric development of thyroid carcinoma in patients with familial adenomatous polyposis. Am. J. Pathol. 157, 1825–1827 (2000)CrossRef
8.
M. De Felice, R. Di Lauro, Thyroid development and its disorders: genetics and molecular mechanisms. Endocr. Rev. 25, 722–746 (2004)CrossRef
9.
M. Nilsson, H. Fagman, Development of the thyroid gland. Development 44, 2123–2140 (2017)CrossRef
10.
B. Xu, K. Yoshimoto, A. Miyauchi et al. Cribriform morular variant of papillary thyroid carcinoma. J. Pathol. 199, 58–67 (2003)CrossRef
11.
F. Cetta, G. Chiappetta, R.M. Melillo et al. The ret/ptc1 oncogene is activated in familial adenomatous associated thyroid papillary carcinoma. J. Clin. Endocrinol. Metab. 83, 1003–1006 (1998)PubMed
12.
A. Bakhsh, G. Kirov, J.W. Gregory et al. A new form of familial multinodular goitre with progression to differentiated thyroid cancer. Endocr. Relat. Cancer 13, 475–483 (2006)CrossRef
13.
A.D. Bakhsh, I. Ladas, M.L. Hamshere et al. An indel in phospholipase-C-B-1 is linked with euthyroid multinodular goitre. Thyroid 28, 891–901 (2018)CrossRef
Metadata
Title
Inherited thyroid tumours
Author
Dillwyn Williams
Publication date
01-05-2020
Publisher
Springer US
Published in
Endocrine / Issue 2/2020
Print ISSN: 1355-008X
Electronic ISSN: 1559-0100
DOI
https://doi.org/10.1007/s12020-020-02252-1

Other articles of this Issue 2/2020

Endocrine 2/2020 Go to the issue

Original Article

Increased autophagy/mitophagy levels in primary tumours of patients with pancreatic neuroendocrine neoplasms

Viewpoint

Autoimmune thyroid disease

Mini Review

Constitutive TSH receptor activation as a hallmark of thyroid autonomy

Original Article

Long-term real-life outcomes in a georrefered cohort of acromegalic patients in Brazil

Original Article

Prediction of hypertension, diabetes and fractures in eucortisolemic women by measuring parameters of cortisol milieu

Original Article

Physiological factors contributing to HbA1c in the normal and pre-diabetic range: a cross-sectional analysis
Live Webinar | 27-06-2024 | 18:00 (CEST)

Keynote webinar | Spotlight on medication adherence

Reserve your place

Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

Join our expert panel to discover why you need to understand the drivers of non-adherence in your patients, and how you can optimize medication adherence in your clinics to drastically improve patient outcomes.

Prof. Kevin Dolgin
Prof. Florian Limbourg
Prof. Anoop Chauhan
Developed by: Springer Medicine
Obesity Clinical Trial Summary

At a glance: The STEP trials

Read more

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Pediatric Cardiology Video

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

Cardiopulmonary Comorbidity Video

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Valvular Heart Disease Video

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

ACC 2024 Congress Coverage

Year in Review: Heart failure and cardiomyopathies

Heart Failure Video

Watch this official video from ACC.24. Dr. Biykem Bozkurt discusses last year's major advances in heart failure and cardiomyopathies.

Watch now

Semaglutide benefits people with type 2 diabetes and obesity-related heart failure

16-04-2024 Type 2 Diabetes News

Incentivised to exercise

11-04-2024 Lifestyle Modifications News

New intervention for STEMI-related cardiogenic shock

10-04-2024 Myocardial Infarction News

» View more highlights on the ACC 2024 congress hub page

Image Credits