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European Archives of Oto-Rhino-Laryngology

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Open Access 05-10-2022 | Glottic Carcinoma | Laryngology

Primary injection laryngoplasty after chordectomy for small glottic carcinomas

Authors: Axelle Felicio-Briegel, Kariem Sharaf, Frank Haubner, Matthias Echternach

Published in: European Archives of Oto-Rhino-Laryngology | Issue 3/2023

Abstract

Objectives

The purpose of this study was to analyze the short- and middle-term effects of primary injection laryngoplasty in patients having tumor resection within the same surgery concerning the vocal outcome. Injection laryngoplasty was performed after harvesting autologous adipose tissue via lipoaspiration.

Methods

A prospective study was performed with 16 patients (2 female; 14 male) who received tumor resection and an injection laryngoplasty using autologous adipose tissue during a single stage procedure. Multidimensional voice evaluation including videostroboscopy, patient self-assessment, voice perception, aerodynamics, and acoustic parameters was performed preoperatively, as well as 1.5, 3 and 6 months postoperatively.

Results

Results show an improvement in the roughness–breathiness–hoarseness (RBH) scale, voice dynamics and subjective voice perception 6 months postoperatively. Maintenance of Voice Handycap Index, jitter and shimmer could be observed 6 months postoperatively. There was no deterioration in RBH and subjective voice perception 2 and 6 weeks postoperatively. No complications occurred in the fat harvesting site.

Conclusions

Using the lipoaspiration and centrifugation approach, primary fat injection laryngoplasty shows short-term maintenance und middle-term improvement in voice quality in patients with vocal fold defect immediately after chordectomy 6 months postoperatively. Cancer recurrence rate is comparable to the reported cancer recurrence rate for laryngeal carcinoma and thus not elevated through primary augmentation.

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Title: Primary injection laryngoplasty after chordectomy for small glottic carcinomas
Authors: Axelle Felicio-Briegel
Kariem Sharaf
Frank Haubner
Matthias Echternach
Publication date: 05-10-2022
Publisher: Springer Berlin Heidelberg
Keyword: Glottic Carcinoma
Published in: European Archives of Oto-Rhino-Laryngology / Issue 3/2023
Print ISSN: 0937-4477
Electronic ISSN: 1434-4726
DOI: https://doi.org/10.1007/s00405-022-07663-6

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Primary injection laryngoplasty after chordectomy for small glottic carcinomas

Abstract

Objectives

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objectives

Methods

Results

Conclusions

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