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Published in: Child's Nervous System 12/2020

01-12-2020 | Glioma | Case Report

Rare occurrence of IDH2 mutation in adolescent oligodendroglioma with 1p/19q co-deletion: a case report

Authors: Shilpa Rao, Sumitra Sivakoti, Arimappamagan Arivazhagan, Vani Santosh

Published in: Child's Nervous System | Issue 12/2020

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Abstract

Adolescent and young adult gliomas are recently being studied as a distinct group and molecular alterations of oligodendroglioma in this group are not well defined. Few studies conducted on adolescent oligodendroglioma so far have found low frequencies of IDH mutations and 1p/19q co-deletion, which are the hallmark genetic alterations seen in adult oligodendroglioma. In this case report, we demonstrate presence of rare IDH2 mutation and 1p/19q co-deletion in an adolescent oligodendroglioma.
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Metadata
Title
Rare occurrence of IDH2 mutation in adolescent oligodendroglioma with 1p/19q co-deletion: a case report
Authors
Shilpa Rao
Sumitra Sivakoti
Arimappamagan Arivazhagan
Vani Santosh
Publication date
01-12-2020
Publisher
Springer Berlin Heidelberg
Published in
Child's Nervous System / Issue 12/2020
Print ISSN: 0256-7040
Electronic ISSN: 1433-0350
DOI
https://doi.org/10.1007/s00381-020-04614-6

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