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01-04-2021 | Glaucoma | Original Paper

Effects of glaucoma and central corneal thickness on optic nerve head biomechanics

Authors: Nilgün Özkan Aksoy, Burçin Çakır, Yakup Ersel Aksoy, Kadriye Demir Boncukçu, Sedat Özmen, Erkan Çelik, Gürsoy Alagöz

Published in: International Ophthalmology | Issue 4/2021

Abstract

Purpose

To evaluate effects of glaucoma and central corneal thickness (CCT) on optic nerve head biomechanics.

Methods

Four groups were formed according to CCT measurements and the presence of glaucoma. Glaucomatous patients with thin (< 510 µ) and thick (> 570 µ) corneas composed groups 1 and 3, respectively. Nonglaucomatous patients with thin and thick corneas composed groups 2 and 4, respectively. Real-time elastography (RTE) was performed on all groups, and optic nerve strain rate (ONSR), orbital fat strain rate (OFSR), and strain ratio of orbital fat to the optic nerve and medial and lateral parts of the optic nerve (SROFON, SROFMON, SROFLON, respectively) were obtained and compared between groups. The correlations between CCT and these parameters were also investigated.

Results

Statistically significant difference was not found between groups in terms of strain rate of optic nerve and orbital fat, SRFON, SROFMON and SROFLON. There was a positive correlation between ONSR and OFSR and mean CCT in patients with CCT thinner than 510 µ (p: 0.03 r: 0.26, p: 0.01 r: 0.32 respectively).

Conclusion

SROFON, SROFLON and SROFMON values did not differ between glaucomatous and nonglaucomatous patients with thin or thick CCTs. The correlations between CCT and OFSR and ONSR were found to be statistically significant in patients with thin CCT.

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Title: Effects of glaucoma and central corneal thickness on optic nerve head biomechanics
Authors: Nilgün Özkan Aksoy
Burçin Çakır
Yakup Ersel Aksoy
Kadriye Demir Boncukçu
Sedat Özmen
Erkan Çelik
Gürsoy Alagöz
Publication date: 01-04-2021
Publisher: Springer Netherlands
Keyword: Glaucoma
Published in: International Ophthalmology / Issue 4/2021
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-020-01686-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Effects of glaucoma and central corneal thickness on optic nerve head biomechanics

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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