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International Ophthalmology

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01-04-2021 | Glaucoma | Original Paper

Evaluating CO₂ laser-assisted sclerectomy surgery with mitomycin C combined with or without phacoemulsification in adult Asian glaucoma subjects

Authors: Dawn Ching Wen Ho, Shamira A. Perera, Myint Htoon Hla, Ching Lin Ho

Published in: International Ophthalmology | Issue 4/2021

Abstract

Purpose

To evaluate and compare outcomes of CO₂ laser-assisted sclerectomy surgery (CLASS) with mitomycin C (MMC) combined with or without phacoemulsification in adult Asian glaucoma patients.

Design

Retrospective, comparative study.

Methods

Adult Asian glaucoma patients who underwent CLASS alone or combined with phacoemulsification using standardized surgery by two trained glaucoma surgeons between 2014 and 2016 were identified. The main measures of outcome were: intraocular pressure (IOP), use of supplemental medical therapy, best-corrected visual acuity (BCVA), microperforations, macroperforations, and repeated intervention(s) for glaucoma.

Results

Forty-one eyes who underwent CLASS alone (13 eyes) or combined with phacoemulsification (28 eyes) were included. Overall, BCVA improved from 0.28 ± 0.19 to 0.14 ± 0.17, and 0.17 ± 0.19, 0.22 ± 0.24, and 0.18 ± 0.23 at 6, 12, 24, and 36 months, respectively. Mean IOP dropped from 17.9 ± 4.7 mmHg to 14.6 ± 5.5, 13.9 ± 3.3, 14.3 ± 3.6, and 14.1 ± 3.7 mmHg, and average number of medications reduced from 2.9 ± 0.9 to 0.2 ± 0.6, 0.5 ± 0.9, 1.0 ± 1.2, and 1.3 ± 1.4 at the same time points. There was no statistically significant difference in BCVA, IOP, and medication reduction between the two groups.

Conclusions

CLASS combined with or without phacoemulsification was equally safe and effective, but yielded more modest results in our population.

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Title: Evaluating CO2 laser-assisted sclerectomy surgery with mitomycin C combined with or without phacoemulsification in adult Asian glaucoma subjects
Authors: Dawn Ching Wen Ho
Shamira A. Perera
Myint Htoon Hla
Ching Lin Ho
Publication date: 01-04-2021
Publisher: Springer Netherlands
Keywords: Glaucoma
Trabeculectomy
CO2 Laser
Cataract
Laser
Published in: International Ophthalmology / Issue 4/2021
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-021-01707-2

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Evaluating CO₂ laser-assisted sclerectomy surgery with mitomycin C combined with or without phacoemulsification in adult Asian glaucoma subjects

Abstract

Purpose

Design

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Design

Methods

Results

Conclusions

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