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International Ophthalmology

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01-05-2021 | Glaucoma | Original Paper

Corneal endothelial status in different grades of late spontaneous in-the-bag IOL dislocation

Authors: Renata Vaiciuliene, Vytautas Jasinskas

Published in: International Ophthalmology | Issue 5/2021

Abstract

Purpose

To evaluate corneal endothelial cell density (ECD) in the eyes with different grades of late spontaneous in-the-bag intraocular lens (IOL) dislocation.

Methods

A prospective study included seventy-eight patients who applied for IOL dislocation. Overall 80 eyes were divided into four grades based on the in-the-bag IOL dislocation classification. All eyes underwent a complete ophthalmological examination. ECD was evaluated using in vivo corneal confocal microscopy.

Results

Median corneal ECD was 1929 (1022–2958) cells/mm2 of all the patients. The lowest number of ECD was in grade 2 (grade 1 median ECD 1990.33 (1182–2425.33) cells/mm2, grade 2—1577.0 (1022–2958) cells/mm2, grade 3—2205.84 (1259–2807.67) cells/mm2 and grade 4—2072.17 (1045–2581.0) cells/mm2). A statistically significant difference was observed between the median of ECD of grade 2nd and 3rd (p = 0.023). By grouping cases into those with and without glaucoma, we found that corneal ECD was significantly lower in eyes with glaucoma compared with eyes without glaucoma in grades 3 and 4 (p < 0.05), while in other grades, the difference did not reach the significance level. We divided the corneal ECD of all eyes into two categories ≤ 1500 cells/mm2 and > 1500 cells/mm2. Logistic regression demonstrated that the odds of having corneal ECD less than 1500 cells/mm2 increased by 3.5-fold if patients with IOL dislocation had been diagnosed with glaucoma previously.

Conclusion

Late spontaneous in-the-bag IOL dislocation reduced corneal ECD. Previously diagnosed glaucoma was the most common comorbidity. This condition has a significant impact on corneal ECD for patients with IOL dislocation.

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Title: Corneal endothelial status in different grades of late spontaneous in-the-bag IOL dislocation
Authors: Renata Vaiciuliene
Vytautas Jasinskas
Publication date: 01-05-2021
Publisher: Springer Netherlands
Keywords: Glaucoma
Cataract
Published in: International Ophthalmology / Issue 5/2021
Print ISSN: 0165-5701
Electronic ISSN: 1573-2630
DOI: https://doi.org/10.1007/s10792-021-01702-7

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Corneal endothelial status in different grades of late spontaneous in-the-bag IOL dislocation

Abstract

Purpose

Methods

Results

Conclusion

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusion

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