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Thrombosis Journal
Published in: Thrombosis Journal 1/2013

Open Access 01-12-2013 | Case report

Giant left atrium associated with massive thrombus formation

Authors: Ahmad K Darwazah, Hamdy El Sayed

Published in: Thrombosis Journal | Issue 1/2013

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Abstract

Giant left atrium is a condition characterized by huge enlargement of the left atrium with a diameter exceeding 65mm. It is most commonly associated with long standing rheumatic mitral valve disease. We present a 45-year-old female patient with rheumatic mitral stenosis associated with giant left atrium occupied by an 11 × 10 × 5 cm thrombus weighing 500 gms. The patient underwent successful mitral valve replacement and thrombectomy through an inverted T-shaped biatrial incision.
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Literature
1.
Hurst W: Memories of patients with a giant left atrium. Circulation 2001, 104: 2630-2631. 10.1161/hc4701.100775CrossRefPubMed
2.
Plaschkes J, Broman JB, Mercin G, Milwidsky H: Giant left atrium in rheumatic heart disease: a report of18 cases treated by mitral valve replacement. Ann Surg 1971, 174: 194-201. 10.1097/00000658-197108000-00004PubMedCentralCrossRefPubMed
3.
Kawazoe K, Beppu S, Takahara Y, Nakajima N, Tanaka K, Ichinashi K, Fujita T, Manabe H: Surgical treatment of giant left atrium combined with mitral valvular disease. Plication procedure for reduction of compression to the left ventricle, bronchus, and pulmonary parenchyma. J Thorac Cardiovasc Surg 1983, 85: 885-892.PubMed
4.
Schwammenthal F, Vered Z, Agranat O, Kaplinsky E, Rabinowitz B, Feinberg MS: Impact of atrioventricular compliance on pulmonary artery pressure in mitral stenosis: an excercise echocardiographic study. Circulation 2000, 102: 2378-2384. 10.1161/01.CIR.102.19.2378CrossRefPubMed
5.
Piccoli GP: Massini C, Di Fusanio G, Rallerini I, Lacobone G, Giant left atrium and mitral valve disease: early and late results of surgical treatment in 40 cass. J Cardiovasc Surg (Torino) 1984, 25: 328-336.
6.
Di Eusanio G, Gregorini R, Mazzola A, Clementi G, Procaccini B, Cavarra F, Tarasch F, Esposito G, Di Nardo W, DiLuzio V: Giant left atrium and mitral valve replacement: risk factor analysis. Eur J Cardio-Thorac Surg 1988, 2: 151-159. 10.1016/1010-7940(88)90063-2CrossRef
7.
Sanfalippo A, Abascal V, Sheehan M, Oertel LB, Harrigan P, Hughes RA, Weyman AE: Atrial enlargement as a consequence of atrial fibrillation. Circulation 1990, 82: 792-797. 10.1161/01.CIR.82.3.792CrossRef
8.
Apostolakis E, Shuhaiber JH: The surgical management of giant left atrium. Eur J Cardiothorac Surg 2008, 33(2):182-190. 10.1016/j.ejcts.2007.11.003CrossRefPubMed
9.
Funk M, Perez M, Santana O: Asymptomatic giant left atrium. Clin Cardiol 2010, 33: E104-E105. 10.1002/clc.20736CrossRefPubMed
10.
Farman MT, Sial JA, Khan N, Rahu QA, Tasneem H, Ishaq H: Severe mitral stenosis with atrial fibrillation-a harbinger of thromboembolism. J Pak Med Assoc 2010, 60(6):439-43.PubMed
11.
Yazici HU, Akcay B, Ozturk U, Tassal A: A giant left atrium. Türk Kardiyol Dern Ars 2010, 38: 223.PubMed
12.
Sinatra R, Pulitani I, Antonazzo A, Melina G: A novel technique for giant left atrium reduction. Eur J Cardiothorc Surg 2001, 20(2):412-414. 10.1016/S1010-7940(01)00802-8CrossRef
13.
Ates M, Sensoz Y, Abay G, Akcar M: Giant left atrium with rheumatic mitral stenosis. Tex Heart Inst J 2006, 33(3):389-391.PubMedCentralPubMed
14.
Goldsmith I, Kumar P, Carter P, Blann AD, Patel RL, Lip GY: Atrial endocardial changes in mitral valve disease: a scanning electron microscopy study. Am Heart J 2000, 140(5):777-84. 10.1067/mhj.2000.110284CrossRefPubMed
15.
Yamamoto K, Ikeda U, Seino Y, Mito H, Fujikawa H, Sekiguchi H, Shimada K: Coagulation activity is increased in the left atrium of patients with mitral stenosis. J Am Coll Cardiol 1995, 25(1):107-12. 10.1016/0735-1097(94)00322-HCrossRefPubMed
16.
Tonguc E, Kestelli M, Özsöyler I, Yilik L, Yilmaz A, Özbek C, Akcay A, Yesil M: Limit of indication for plication of giant left atrium. Asian Cardiovasc Thorac Ann 2001, 9: 24-26.CrossRef
17.
Kutay V, Kirali K, Ekim H, Yakut C: Effects of giant left atrium on thromboembolism after mitral valve replacement. Asian Cardiovasc Thorac Ann 2005, 13: 107-111.CrossRefPubMed
18.
Lim C, Rhyu WH, Lee Y, Choh JH: Management of left atrial endocardium after extensive thrombectomy. Ann Thorac Surg 2005, 79: e11-e12. 10.1016/j.athoracsur.2004.09.031CrossRefPubMed
19.
Ageno W, Turpie AG, Steidl L, Ambrosini F, Cattaneo R, Codari RL, Nardo B, Venco A: Comparison of a daily fixed 2.5-mg warfarin dose with a 5-mg, international normalized ratio adjusted, warfarin dose initially following heart valve replacement. Am J Cardiol 2001, 88: 40-44. 10.1016/S0002-9149(01)01582-XCrossRefPubMed
20.
Bonow RO, Carabello AB, Chatterjee K, Jr AC Dl, Faxon DP, Freed MD, Gaasch WH, Lytle BW, Nishimura RA, O’Gara PT, O’Rourke RA, Otto CM, Shah PM, Shanewise JS: ACC/AHA 2006 Guidelines for the treatment of patients with valvular heart disease. A report of the american college of cardiology/american heart association task force on practice guidelines (writing committe to revise the 1998 guidelines for the management of patients with valvular heart disease. Circulation 2006, 114: e84-e231. 10.1161/CIRCULATIONAHA.106.176857CrossRefPubMed
21.
Kulik A, Rubens FD, Wells PS, Kearon C, Mesana TG, van Berkom J, Lam BK: Early postoperative anticoagulation after mechanical valve replacement: A systematic review. Ann Thorac surg 2006, 81: 770-781. 10.1016/j.athoracsur.2005.07.023CrossRefPubMed
Metadata
Title
Giant left atrium associated with massive thrombus formation
Authors
Ahmad K Darwazah
Hamdy El Sayed
Publication date
01-12-2013
Publisher
BioMed Central
Published in
Thrombosis Journal / Issue 1/2013
Electronic ISSN: 1477-9560
DOI
https://doi.org/10.1186/1477-9560-11-5

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