Published in:
Open Access
01-12-2019 | Giant Cell Arteritis | Research article
RETRACTED ARTICLE: Ultrasound versus temporal artery biopsy in patients with Giant
cell arteritis: a prospective cohort study
Authors:
Quan Zou, Sumei Ma, Xinghu Zhou
Published in:
BMC Medical Imaging
|
Issue 1/2019
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Abstract
Background
Diagnosis of giant cell arteritis by temporal artery biopsy is
time-consuming and visual loss lies in the first week after its diagnosis. The
purpose of the study was to test the hypothesis that ultrasound can reduce the
risk of overdiagnosis and overtreatment in giant cell arteritis.
Methods
Data regarding physical/ clinical features examinations, temporal
artery biopsy examinations, ultrasound findings, and magnetic resonance imaging
examinations of 980 suspected patients for giant cell arteritis were included in
the study. Decision curve analysis was applied to get a beneficial score for
selected diagnostic modalities. Cost analysis was performed for each
patient.
Results
Fewer numbers of false positive giant cell arteritis results were
reported under physical/ clinical features examinations following ultrasound
detection than physical/clinical features examinations following temporal artery
biopsy examinations (45 vs. 127, p < 0.0001). The working area that detects giant cell arteritis
at least one time for physical/ clinical features examinations following
ultrasound detection and physical/ clinical features examinations following
temporal artery biopsy examinations were 0–91% and 0–86%. No significant
difference for true negative results between magnetic resonance imaging and
physical and clinical features examinations following ultrasound detection
(p = 0.007). Physical and clinical
features examinations following ultrasound detection were less expensive method
than physical/ clinical features examinations following temporal artery biopsy
examinations (14,023 ± 982 ¥/patient vs. 18,551 ± 1231 ¥/patient, p < 0.0001) and MRI.
Conclusion
Physical and clinical features examinations following ultrasound are
recommended for diagnosis of patients with suspected giant cell
arteritis.