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Arthritis Research & Therapy
Published in: Arthritis Research & Therapy 1/2012

Open Access 01-12-2012 | Poster presentation

GI-REASONS: a novel 6-month, prospective, randomized, open-label, blinded end point (PROBE) trial

Authors: Byron Cryer, Chunming Li, Lee S Simon, Gurkirpal Singh, Martin J Stillman, Manuela Berger

Published in: Arthritis Research & Therapy | Special Issue 1/2012

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Excerpt

The GI Randomized Event and Safety Open-Label NSAID Study (GI-REASONS) was a novel prospective, randomized, open-label, blinded end point (PROBE) study that measured adjudicated clinical outcomes throughout the GI tract. It was designed to assess if celecoxib use in patients with osteoarthritis (OA) at moderate GI risk (≥55 y) is associated with a lower incidence of clinically significant upper and lower GI events compared to nsNSAIDs, with/without proton-pump inhibitors (PPIs), in standard US clinical practice. …
Metadata
Title
GI-REASONS: a novel 6-month, prospective, randomized, open-label, blinded end point (PROBE) trial
Authors
Byron Cryer
Chunming Li
Lee S Simon
Gurkirpal Singh
Martin J Stillman
Manuela Berger
Publication date
01-12-2012
Publisher
BioMed Central
Published in
Arthritis Research & Therapy / Issue Special Issue 1/2012
Electronic ISSN: 1478-6362
DOI
https://doi.org/10.1186/ar3664

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Keynote webinar | Spotlight on medication adherence

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Live: Thursday 27th June 2024, 18:00-19:30 (CEST)

WHO estimates that half of all patients worldwide are non-adherent to their prescribed medication. The consequences of poor adherence can be catastrophic, on both the individual and population level.

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Prof. Kevin Dolgin
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Developed by: Springer Medicine
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Developed by: Springer Medicine

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