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01-04-2011 | Original Research

Genetic Counseling for Early-onset Familial Alzheimer Disease in Large Aboriginal Kindred from a Remote Community in British Columbia: Unique Challenges and Possible Solutions

Authors: Rachel Butler, Emily Dwosh, B. Lynn Beattie, Colleen Guimond, Sofia Lombera, Elana Brief, Judy Illes, A. Dessa Sadovnick

Published in: Journal of Genetic Counseling | Issue 2/2011

Abstract

A novel, pathogenic presenilin 1 (PS1) mutation has recently been identified in a large Aboriginal kindred living in dispersed communities throughout British Columbia, Canada. Disseminating genetic information and ensuring that appropriate genetic counseling services are provided to all concerned relatives have posed several unique challenges. These challenges include knowledge exchange and continuity of care in a geographically remote and culturally distinct community. To our knowledge, this is the first time a specific genetic counseling approach has been needed for early-onset familial Alzheimer disease (EOFAD) in a North American Aboriginal community.

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Title: Genetic Counseling for Early-onset Familial Alzheimer Disease in Large Aboriginal Kindred from a Remote Community in British Columbia: Unique Challenges and Possible Solutions
Authors: Rachel Butler
Emily Dwosh
B. Lynn Beattie
Colleen Guimond
Sofia Lombera
Elana Brief
Judy Illes
A. Dessa Sadovnick
Publication date: 01-04-2011
Publisher: Springer US
Published in: Journal of Genetic Counseling / Issue 2/2011
Print ISSN: 1059-7700
Electronic ISSN: 1573-3599
DOI: https://doi.org/10.1007/s10897-010-9334-9

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Genetic Counseling for Early-onset Familial Alzheimer Disease in Large Aboriginal Kindred from a Remote Community in British Columbia: Unique Challenges and Possible Solutions

Abstract

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

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