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Open Access 01-12-2019 | Gastrointestinal Stromal Tumor | Dynamic Manuscript

Clinical feasibility and safety of third space robotic and endoscopic cooperative surgery for gastric gastrointestinal stromal tumors dissection

A new surgical technique for treating gastric GISTs

Authors: Feiyu Shi, Yingchao Li, Yanglin Pan, Qi Sun, Guanghui Wang, Tianyu Yu, Chengxin Shi, Yaguang Li, Hongping Xia, Junjun She

Published in: Surgical Endoscopy | Issue 12/2019

Abstract

Background

Surgical management of gastric gastrointestinal stromal tumors (GISTs) has evolved towards minimal invasiveness. Laparoscopic wedge resection and laparoscopic and endoscopic cooperative surgery had been considered as standard surgical treatments for gastric GISTs > 2 cm. However, stomach deformation and the full-thickness gastric defect caused by these procedures may increase the risk of morbidity. To address these problems, we developed a novel technique, third space robotic and endoscopic cooperative surgery (TS-RECS), which could dissect the tumor entirely while preserving the intact mucosal layer. Here we performed a prospective evaluation of the feasibility and safety of TS-RECS.

Methods

Patients with gastric GISTs were recruited between April 2018 and April 2019. During the operation, the gastric GIST was located by endoscopic view firstly and the submucosal injection was performed. The tumor was then dissected through robotic surgery. Clinicopathological characteristics, operative data, adverse events, and follow-ups were prospectively collected and analyzed.

Results

A total of 20 patients with gastric GISTs received TS-RECS. The mean tumor size was 33.0 ± 7.3 mm. R0 resection was achieved in all patients with a median operation time of 115 min and a median blood loss of 20 ml. The integrity of mucosal layer was maintained in 95% (19/20) of the patients. All patients started oral diet on postoperative day 1 or 2, staying in the hospital for a median of 6 days after surgery. There were no major adverse events. Local or distant recurrences were not observed during a median follow-up period of 10 months.

Conclusions

Our study suggests that TS-RECS appears to be a feasible and safe technique which could be an alternative method for resecting gastric GISTs > 2 cm.

Clinical Trials

ClinicalTrials.gov NCT03804762.

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Title: Clinical feasibility and safety of third space robotic and endoscopic cooperative surgery for gastric gastrointestinal stromal tumors dissection
A new surgical technique for treating gastric GISTs
Authors: Feiyu Shi
Yingchao Li
Yanglin Pan
Qi Sun
Guanghui Wang
Tianyu Yu
Chengxin Shi
Yaguang Li
Hongping Xia
Junjun She
Publication date: 01-12-2019
Publisher: Springer US
Keyword: Gastrointestinal Stromal Tumor
Published in: Surgical Endoscopy / Issue 12/2019
Print ISSN: 0930-2794
Electronic ISSN: 1432-2218
DOI: https://doi.org/10.1007/s00464-019-07223-w

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Clinical feasibility and safety of third space robotic and endoscopic cooperative surgery for gastric gastrointestinal stromal tumors dissection

A new surgical technique for treating gastric GISTs

Abstract

Background

Methods

Results

Conclusions

Clinical Trials

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Results

Conclusions

Clinical Trials

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