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Open Access 14-04-2023 | Gastroenterostomy

Innovations in the Treatment of Gastric Outlet Obstruction: Is This the Era of Endoscopic Ultrasonography-Guided Gastroenterostomy?

Authors: Yorick L. van de Pavert, MD, MA, Leon M. G. Moons, MD, PhD, Auke Bogte, MD, PhD, Frank P. Vleggaar, MD, PhD

Published in: Current Treatment Options in Gastroenterology

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Abstract

Purpose of review

Gastric outlet obstruction is a syndrome that is caused by several benign and malignant diseases. Endoscopic ultrasonography-guided gastroenterostomy (EUS-GE) is a novel treatment that seems to combine the advantages of the two traditional treatments: enteral stent placement (ES) and surgical gastrojejunostomy (SGJ). This review aims to determine the current position of EUS-GE amidst the two traditional treatment options.

Recent findings

Different approaches can be adopted to facilitate EUS-GE. Direct gastroenterostomy seems to have the shortest procedure time. All methods possess high technical success rates. Several retrospective analyses have compared EUS-GE to ES and SGJ. EUS-GE seems to have better stent patency compared to ES and a lower adverse event rate compared to SGJ. Recently, randomized trials have been initiated which compare EUS-GE with ES or SGJ.

Summary

Although the currently published literature unequivocally shows the great promises of EUS-GE, properly powered and controlled studies are warranted to ascertain the definitive position of EUS-GE within the treatment repertoire of GOO. Until reliable data has been collected, EUS-GE can be considered a safe and effective alternative to ES and SGJ.
Literature
2.•
go back to reference Jue TL, Storm AC, Naveed M, Fishman DS, Qumseya BJ, McRee AJ, et al. ASGE guideline on the role of endoscopy in the management of benign and malignant gastroduodenal obstruction. Gastrointest Endosc. 2021;93:309–322.e4. https://doi.org/10.1016/j.gie.2020.07.063. ASGE guideline on the management of benign and malignant gastroduodenal obstruction. Jue TL, Storm AC, Naveed M, Fishman DS, Qumseya BJ, McRee AJ, et al. ASGE guideline on the role of endoscopy in the management of benign and malignant gastroduodenal obstruction. Gastrointest Endosc. 2021;93:309–322.e4. https://​doi.​org/​10.​1016/​j.​gie.​2020.​07.​063. ASGE guideline on the management of benign and malignant gastroduodenal obstruction.
9.
go back to reference Boghossian MB, Funari MP, de Moura DTH, McCarty TR, Sagae VMT, Chen Y, et al. EUS-guided gastroenterostomy versus duodenal stent placement and surgical gastrojejunostomy for the palliation of malignant gastric outlet obstruction: a systematic review and meta-analysis. Langenbecks Arch Surg. 2021;406:1803–17. https://doi.org/10.1007/s00423-021-02215-8.CrossRefPubMed Boghossian MB, Funari MP, de Moura DTH, McCarty TR, Sagae VMT, Chen Y, et al. EUS-guided gastroenterostomy versus duodenal stent placement and surgical gastrojejunostomy for the palliation of malignant gastric outlet obstruction: a systematic review and meta-analysis. Langenbecks Arch Surg. 2021;406:1803–17. https://​doi.​org/​10.​1007/​s00423-021-02215-8.CrossRefPubMed
30.
go back to reference Ribas PHBV, de Moura DTH, Proença IM, do Monte Júnior ES, Yvamoto EY, Hemerly MC, et al. Endoscopic ultrasound-guided gastroenterostomy for the palliation of gastric outlet obstruction (GOO): a systematic review and meta-analysis of the different techniques. Cureus. 2022;14:e31526. https://doi.org/10.7759/cureus.31526. Ribas PHBV, de Moura DTH, Proença IM, do Monte Júnior ES, Yvamoto EY, Hemerly MC, et al. Endoscopic ultrasound-guided gastroenterostomy for the palliation of gastric outlet obstruction (GOO): a systematic review and meta-analysis of the different techniques. Cureus. 2022;14:e31526. https://​doi.​org/​10.​7759/​cureus.​31526.
36.•
go back to reference Bejjani M, Ghandour B, Subtil JC, Martínez-Moreno B, Sharaiha RZ, Watson RR, et al. Clinical and technical outcomes of patients undergoing endoscopic ultrasound-guided gastroenterostomy using 20-mm vs. 15-mm lumen-apposing metal stents. Endoscopy. 2022;54:680–7. https://doi.org/10.1055/a-1654-6914. Retrospective study comparing 20 mm with 15 mm LAMS. Bejjani M, Ghandour B, Subtil JC, Martínez-Moreno B, Sharaiha RZ, Watson RR, et al. Clinical and technical outcomes of patients undergoing endoscopic ultrasound-guided gastroenterostomy using 20-mm vs. 15-mm lumen-apposing metal stents. Endoscopy. 2022;54:680–7. https://​doi.​org/​10.​1055/​a-1654-6914. Retrospective study comparing 20 mm with 15 mm LAMS.
40.•
go back to reference Ghandour B, Bejjani M, Irani SS, Sharaiha RZ, Kowalski TE, Pleskow DK, et al. Classification, outcomes, and management of misdeployed stents during EUS-guided gastroenterostomy. Gastrointest Endosc. 2022;95:80–9. https://doi.org/10.1016/j.gie.2021.07.023. Retrospective study describing outcomes and management of EUS-GE misdeployment. Ghandour B, Bejjani M, Irani SS, Sharaiha RZ, Kowalski TE, Pleskow DK, et al. Classification, outcomes, and management of misdeployed stents during EUS-guided gastroenterostomy. Gastrointest Endosc. 2022;95:80–9. https://​doi.​org/​10.​1016/​j.​gie.​2021.​07.​023. Retrospective study describing outcomes and management of EUS-GE misdeployment.
45.
go back to reference Taibi A, Durand Fontanier S, Derbal S, Lepetit H, Christou N, Fredon F, et al. What is the ideal indwelling time for metal stents after endoscopic ultrasound-guided gastrojejunostomy? Case report of delayed iatrogenic perforation with a review of the literature. Dig Endosc. 2020;32:816–22. https://doi.org/10.1111/den.13645.CrossRefPubMed Taibi A, Durand Fontanier S, Derbal S, Lepetit H, Christou N, Fredon F, et al. What is the ideal indwelling time for metal stents after endoscopic ultrasound-guided gastrojejunostomy? Case report of delayed iatrogenic perforation with a review of the literature. Dig Endosc. 2020;32:816–22. https://​doi.​org/​10.​1111/​den.​13645.CrossRefPubMed
46.••
47.••
go back to reference Chen YI, Itoi T, Baron TH, Nieto J, Haito-Chavez Y, Grimm IS, et al. EUS-guided gastroenterostomy is comparable to enteral stenting with fewer re-interventions in malignant gastric outlet obstruction. Surg Endosc. 2017;31:2946–52. https://doi.org/10.1007/s00464-016-5311-1. Retrospective comparison of EUS-GE and ES. Chen YI, Itoi T, Baron TH, Nieto J, Haito-Chavez Y, Grimm IS, et al. EUS-guided gastroenterostomy is comparable to enteral stenting with fewer re-interventions in malignant gastric outlet obstruction. Surg Endosc. 2017;31:2946–52. https://​doi.​org/​10.​1007/​s00464-016-5311-1. Retrospective comparison of EUS-GE and ES.
48.••
go back to reference van Wanrooij RLJ, Vanella G, Bronswijk M, de Gooyer P, Laleman W, van Malenstein H, et al. Endoscopic ultrasound-guided gastroenterostomy versus duodenal stenting for malignant gastric outlet obstruction: an international, multicenter, propensity score-matched comparison. Endoscopy. 2022;54:1023–31. https://doi.org/10.1055/a-1782-7568. Retrospective comparison of EUS-GE and ES. van Wanrooij RLJ, Vanella G, Bronswijk M, de Gooyer P, Laleman W, van Malenstein H, et al. Endoscopic ultrasound-guided gastroenterostomy versus duodenal stenting for malignant gastric outlet obstruction: an international, multicenter, propensity score-matched comparison. Endoscopy. 2022;54:1023–31. https://​doi.​org/​10.​1055/​a-1782-7568. Retrospective comparison of EUS-GE and ES.
49.••
go back to reference Sánchez-Aldehuelo R, Subtil Iñigo JC, Martínez Moreno B, Gornals J, Guarner-Argente C, Repiso Ortega A, et al. EUS-guided gastroenterostomy versus duodenal self-expandable metal stent for malignant gastric outlet obstruction: results from a nationwide multicenter retrospective study (with video). Gastrointest Endosc. 2022;96:1012–1020.e3. https://doi.org/10.1016/j.gie.2022.07.018. Retrospective comparison of EUS-GE and ES. Sánchez-Aldehuelo R, Subtil Iñigo JC, Martínez Moreno B, Gornals J, Guarner-Argente C, Repiso Ortega A, et al. EUS-guided gastroenterostomy versus duodenal self-expandable metal stent for malignant gastric outlet obstruction: results from a nationwide multicenter retrospective study (with video). Gastrointest Endosc. 2022;96:1012–1020.e3. https://​doi.​org/​10.​1016/​j.​gie.​2022.​07.​018. Retrospective comparison of EUS-GE and ES.
50.••
go back to reference Chan SM, Dhir V, Chan YYY, Cheung CHN, Chow JCS, Wong IWM, et al. Endoscopic ultrasound-guided balloon-occluded gastrojejunostomy bypass, duodenal stent or laparoscopic gastrojejunostomy for unresectable malignant gastric outlet obstruction. Dig Endosc. 2022. https://doi.org/10.1111/den.14472. Retrospective comparison of EUS-GE, ES, and SGJ. Chan SM, Dhir V, Chan YYY, Cheung CHN, Chow JCS, Wong IWM, et al. Endoscopic ultrasound-guided balloon-occluded gastrojejunostomy bypass, duodenal stent or laparoscopic gastrojejunostomy for unresectable malignant gastric outlet obstruction. Dig Endosc. 2022. https://​doi.​org/​10.​1111/​den.​14472. Retrospective comparison of EUS-GE, ES, and SGJ.
51.••
go back to reference Jaruvongvanich V, Mahmoud T, Abu Dayyeh BK, Chandrasekhara V, Law R, Storm AC, et al. Endoscopic ultrasound-guided gastroenterostomy for the management of gastric outlet obstruction: a large comparative study with long-term follow-up. Endosc Int Open. 2022;11:E60–E66. https://doi.org/10.1055/a-1976-2279. Retrospective comparison of EUS-GE, ES, and SGJ. Jaruvongvanich V, Mahmoud T, Abu Dayyeh BK, Chandrasekhara V, Law R, Storm AC, et al. Endoscopic ultrasound-guided gastroenterostomy for the management of gastric outlet obstruction: a large comparative study with long-term follow-up. Endosc Int Open. 2022;11:E60–E66. https://​doi.​org/​10.​1055/​a-1976-2279. Retrospective comparison of EUS-GE, ES, and SGJ.
52.•
go back to reference van der Merwe SW, van Wanrooij RLJ, Bronswijk M, Everett S, Lakhtakia S, Rimbas M, et al. Therapeutic endoscopic ultrasound: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy. 2022;54:185–205. https://doi.org/10.1055/a-1717-1391.ESGE guideline regarding EUS-guided interventions. van der Merwe SW, van Wanrooij RLJ, Bronswijk M, Everett S, Lakhtakia S, Rimbas M, et al. Therapeutic endoscopic ultrasound: European Society of Gastrointestinal Endoscopy (ESGE) Guideline. Endoscopy. 2022;54:185–205. https://​doi.​org/​10.​1055/​a-1717-1391.ESGE guideline regarding EUS-guided interventions.
53.••
go back to reference Perez-Miranda M, Tyberg A, Poletto D, Toscano E, Gaidhane M, Desai AP, et al. EUS-guided gastrojejunostomy versus laparoscopic gastrojejunostomy: an international collaborative study. J Clin Gastroenterol. 2017;51:896–9. https://doi.org/10.1097/MCG.0000000000000887. Retrospective comparison of EUS-GE and SGJ. Perez-Miranda M, Tyberg A, Poletto D, Toscano E, Gaidhane M, Desai AP, et al. EUS-guided gastrojejunostomy versus laparoscopic gastrojejunostomy: an international collaborative study. J Clin Gastroenterol. 2017;51:896–9. https://​doi.​org/​10.​1097/​MCG.​0000000000000887​. Retrospective comparison of EUS-GE and SGJ.
54.••
go back to reference Bronswijk M, Vanella G, van Malenstein H, Laleman W, Jaekers J, Topal B, et al. Laparoscopic versus EUS-guided gastroenterostomy for gastric outlet obstruction: an international multicenter propensity score-matched comparison (with video). Gastrointest Endosc. 2021;94:526–536.e2. https://doi.org/10.1016/j.gie.2021.04.006. Retrospective comparison of EUS-GE and SGJ. Bronswijk M, Vanella G, van Malenstein H, Laleman W, Jaekers J, Topal B, et al. Laparoscopic versus EUS-guided gastroenterostomy for gastric outlet obstruction: an international multicenter propensity score-matched comparison (with video). Gastrointest Endosc. 2021;94:526–536.e2. https://​doi.​org/​10.​1016/​j.​gie.​2021.​04.​006. Retrospective comparison of EUS-GE and SGJ.
55.••
go back to reference Kouanda A, Binmoeller K, Hamerski C, Nett A, Bernabe J, Watson R. Endoscopic ultrasound-guided gastroenterostomy versus open surgical gastrojejunostomy: clinical outcomes and cost effectiveness analysis. Surg Endosc. 2021;35:7058–67. https://doi.org/10.1007/s00464-020-08221-z. Retrospective comparison of EUS-GE and SGJ. Kouanda A, Binmoeller K, Hamerski C, Nett A, Bernabe J, Watson R. Endoscopic ultrasound-guided gastroenterostomy versus open surgical gastrojejunostomy: clinical outcomes and cost effectiveness analysis. Surg Endosc. 2021;35:7058–67. https://​doi.​org/​10.​1007/​s00464-020-08221-z. Retrospective comparison of EUS-GE and SGJ.
56.••
go back to reference Abbas A, Dolan RD, Bazarbashi AN, Thompson CC. Endoscopic ultrasound-guided gastroenterostomy versus surgical gastrojejunostomy for the palliation of gastric outlet obstruction in patients with peritoneal carcinomatosis. Endoscopy. 2022;54:671–9. https://doi.org/10.1055/a-1708-0037. Retrospective comparison of EUS-GE and SGJ in patients with peritoneal carcinomatosis. Abbas A, Dolan RD, Bazarbashi AN, Thompson CC. Endoscopic ultrasound-guided gastroenterostomy versus surgical gastrojejunostomy for the palliation of gastric outlet obstruction in patients with peritoneal carcinomatosis. Endoscopy. 2022;54:671–9. https://​doi.​org/​10.​1055/​a-1708-0037. Retrospective comparison of EUS-GE and SGJ in patients with peritoneal carcinomatosis.
57.••
go back to reference Khashab MA, Bukhari M, Baron TH, Nieto J, el Zein M, Chen Y-I, et al. International multicenter comparative trial of endoscopic ultrasonography-guided gastroenterostomy versus surgical gastrojejunostomy for the treatment of malignant gastric outlet obstruction. Endosc Int Open. 2017;5:E275–81. https://doi.org/10.1055/s-0043-101695. Retrospective comparison of EUS-GE and SGJ. Khashab MA, Bukhari M, Baron TH, Nieto J, el Zein M, Chen Y-I, et al. International multicenter comparative trial of endoscopic ultrasonography-guided gastroenterostomy versus surgical gastrojejunostomy for the treatment of malignant gastric outlet obstruction. Endosc Int Open. 2017;5:E275–81. https://​doi.​org/​10.​1055/​s-0043-101695. Retrospective comparison of EUS-GE and SGJ.
62.•
go back to reference Vanella G, Bronswijk M, van Wanrooij RL, Dell’Anna G, Laleman W, van Malenstein H, et al. Combined endoscopic management of biliary and gastric outlet obstruction (CABRIOLET Study): a multicenter retrospective analysis. DEN Open. 2023;3. https://doi.org/10.1002/deo2.132. Retrospective study focusing on the optimal management of concomitant biliary and gastric outlet obstruction. Vanella G, Bronswijk M, van Wanrooij RL, Dell’Anna G, Laleman W, van Malenstein H, et al. Combined endoscopic management of biliary and gastric outlet obstruction (CABRIOLET Study): a multicenter retrospective analysis. DEN Open. 2023;3. https://​doi.​org/​10.​1002/​deo2.​132. Retrospective study focusing on the optimal management of concomitant biliary and gastric outlet obstruction.
63.•
go back to reference Bednarsch J, Czigany Z, Heise D, Zimmermann H, Boecker J, Ulmer TF, et al. Influence of peritoneal carcinomatosis on perioperative outcome in palliative gastric bypass for malignant gastric outlet obstruction - a retrospective cohort study. World J Surg Oncol. 2020;18:25. https://doi.org/10.1186/s12957-020-1803-5. Retrospective study assessing patients with gastric outlet obstruction and ascites who underwent EUS-GE. Bednarsch J, Czigany Z, Heise D, Zimmermann H, Boecker J, Ulmer TF, et al. Influence of peritoneal carcinomatosis on perioperative outcome in palliative gastric bypass for malignant gastric outlet obstruction - a retrospective cohort study. World J Surg Oncol. 2020;18:25. https://​doi.​org/​10.​1186/​s12957-020-1803-5. Retrospective study assessing patients with gastric outlet obstruction and ascites who underwent EUS-GE.
65.
Metadata
Title
Innovations in the Treatment of Gastric Outlet Obstruction: Is This the Era of Endoscopic Ultrasonography-Guided Gastroenterostomy?
Authors
Yorick L. van de Pavert, MD, MA
Leon M. G. Moons, MD, PhD
Auke Bogte, MD, PhD
Frank P. Vleggaar, MD, PhD
Publication date
14-04-2023
Publisher
Springer US
Published in
Current Treatment Options in Gastroenterology
Print ISSN: 1092-8472
Electronic ISSN: 1534-309X
DOI
https://doi.org/10.1007/s11938-023-00417-1
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