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Surgery Today

23-04-2024 | Gastric Cancer | Original Article

Using the geriatric nutritional risk index to predict outcomes in older patients with remnant gastric cancer after gastrectomy: a retrospective multicenter study in Japan

Authors: Tomoyuki Matsunaga, Hiroaki Saito, Tomohiro Osaki, Kenji Fukuda, Yoji Fukumoto, Sadamu Takahashi, Kenjiro Taniguchi, Akemi Iwamoto, Hirohiko Kuroda, Kuniyuki Katano, Shota Shimizu, Yuji Shishido, Kozo Miyatani, Teruhisa Sakamoto, Yoshiyuki Fujiwara

Published in: Surgery Today

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Abstract

Purpose

This study investigated the prognostic value of the geriatric nutritional risk index (GNRI) in patients undergoing curative gastrectomy for remnant gastric cancer (RGC).

Methods

This multicenter retrospective study included 105 patients with RGC of ≥ 65 years of age who underwent curative gastrectomy at 10 institutions in Japan between January 2000 and December 2016. Postoperative complications, overall survival (OS), and disease-specific survival (DSS) were analyzed.

Results

Receiver operating curve analyses indicated that the optimal cutoff value of the GNRI for OS was 95.4. Patients were categorized into high and low GNRI groups based on the optimal GNRI cutoff value. The GNRI was significantly correlated with body mass index (p < 0.001), amount of bleeding (p = 0.021), Clavien–Dindo grade 5 postoperative complications (p = 0.040), death caused by primary disease (p = 0.010), and death caused by other diseases (p = 0.002). The OS and DSS were significantly worse in the low GNRI group. A low GNRI and T3 or deeper tumor invasion were independent prognostic factors for OS and DSS.

Conclusions

The GNRI is a promising predictor of both short- and long-term outcomes in older patients with RGC.
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Metadata
Title
Using the geriatric nutritional risk index to predict outcomes in older patients with remnant gastric cancer after gastrectomy: a retrospective multicenter study in Japan
Authors
Tomoyuki Matsunaga
Hiroaki Saito
Tomohiro Osaki
Kenji Fukuda
Yoji Fukumoto
Sadamu Takahashi
Kenjiro Taniguchi
Akemi Iwamoto
Hirohiko Kuroda
Kuniyuki Katano
Shota Shimizu
Yuji Shishido
Kozo Miyatani
Teruhisa Sakamoto
Yoshiyuki Fujiwara
Publication date
23-04-2024
Publisher
Springer Nature Singapore
Published in
Surgery Today
Print ISSN: 0941-1291
Electronic ISSN: 1436-2813
DOI
https://doi.org/10.1007/s00595-024-02850-w