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Open Access 01-12-2022 | Gastrectomy | Study protocol

Efficacy and safety of long-term transcutaneous electroacupuncture versus sham transcutaneous electroacupuncture for delayed gastric emptying after distal gastrectomy: study protocol for a randomized, patient-assessor blinded, controlled trial

Authors: Kai-Bo Chen, Zhi-Wei Wu, Jun Wang, Ling-Hua Zhu, Xiao-Li Jin, Guo-Feng Chen, Mu-Xing Kang, Yi Huang, Hang Zhang, Le-Le Lin, Di-Ke Shi, Dan Wu, Jian-Feng Chen, Jian Chen, Zhi-Qing Zhao

Published in: Trials | Issue 1/2022

Abstract

Background

Delayed gastric emptying (DGE) after distal gastrectomy impacts patients’ nutritional status and quality of life. The current treatments of DGE seem unsatisfactory or need invasive interventions. It is unknown whether transcutaneous electroacupuncture (TEA) is effective in treating DGE.

Methods

A total of 90 eligible participants who underwent distal gastrectomy will be randomly allocated to either the TEA group (n = 60) or the sham transcutaneous electroacupuncture (sham-TEA) group (n = 30). Each participant will receive TEA on the bilateral acupoints of Zusanli (ST36) and Neiguan (PC6) for 4 weeks. The primary outcomes will be the residual rates of radioactivity in the stomach by gastric scintigraphy and total response rates. The secondary outcomes will be endoscopic features, autonomic function, nutritional and psychological status, serum examination, and quality of life (QoL). The adverse events will also be reported. The patients will be followed up 1 year after the treatment.

Discussion

The findings of this randomized trial will provide high-quality evidence regarding the efficacy and safety of long-term TEA for treating DGE after distal gastrectomy.

Trial registration

Chinese Clinical Trial Registry ChiCTR2000033965. Registered on 20 June 2020

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Title: Efficacy and safety of long-term transcutaneous electroacupuncture versus sham transcutaneous electroacupuncture for delayed gastric emptying after distal gastrectomy: study protocol for a randomized, patient-assessor blinded, controlled trial
Authors: Kai-Bo Chen
Zhi-Wei Wu
Jun Wang
Ling-Hua Zhu
Xiao-Li Jin
Guo-Feng Chen
Mu-Xing Kang
Yi Huang
Hang Zhang
Le-Le Lin
Di-Ke Shi
Dan Wu
Jian-Feng Chen
Jian Chen
Zhi-Qing Zhao
Publication date: 01-12-2022
Publisher: BioMed Central
Keywords: Gastrectomy
Gastric Cancer
Gastric Cancer
Gastrectomy
Published in: Trials / Issue 1/2022
Electronic ISSN: 1745-6215
DOI: https://doi.org/10.1186/s13063-022-06108-z

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Springer Medicine

Efficacy and safety of long-term transcutaneous electroacupuncture versus sham transcutaneous electroacupuncture for delayed gastric emptying after distal gastrectomy: study protocol for a randomized, patient-assessor blinded, controlled trial

Abstract

Background

Methods

Discussion

Trial registration

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Methods

Discussion

Trial registration

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