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Open Access 01-08-2009 | Gastrointestinal Oncology

Gallbladder Cancer: We Need to Do Better!

Authors: Parul J. Shukla, MBBS, MS, FRCS, Savio G. Barreto, MBBS, MS

Published in: Annals of Surgical Oncology | Issue 8/2009

Excerpt

Gallbladder cancer is associated with a dismal prognosis, with a 5-year survival rate of <5% for those patients with disease not amenable to surgery.1,2 In some parts of the world, the incidence is comparatively high and contributes to a social disaster as a result of its associated poor outcome. Even among patients who undergo radical surgical resection, the reported median survival across all stages is 35% to 38%.2,3 …

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Dixon E, Vollmer C, Sahajpal A, et al. An aggressive surgical approach leads to improved survival in patients with gallbladder cancer. Ann Surg. 2005;241:385–94.PubMedCrossRef

Foster JM, Hoshi H, Gibbs JF, et al. Gallbladder cancer: defining the indications for primary radical resection and radical reresection. Ann Surg Oncol. 2007;14:833–40.PubMedCrossRef

Chan SY, Poon RT, Lo CM, et al. Management of carcinoma of the gallbladder: a single-institution experience in 16 years. J Surg Oncol. 2008;97:156–64.PubMedCrossRef

Shukla PJ, Barreto G, Kakade A, Shrikhande SV. Revision surgery for gallbladder cancer: factors influencing operability and further evidence for T1b tumours. HPB (Oxford). 2008;10:43–7.

Kondo S, Takada T, Miyazaki M; Japanese Association of Biliary Surgery; Japanese Society of Hepato-Biliary-Pancreatic Surgery; Japan Society of Clinical Oncology. Guidelines for the management of biliary tract and ampullary carcinomas: surgical treatment. J Hepatobiliary Pancreat Surg. 2008;15:41–4.PubMedCrossRef

Shukla PJ, Barreto SG. Approach to carcinoma of the gallbladder. In: Roshan Lall Gupta, editor. Recent Advances in Surgery 11. Indian ed. New Delhi: Jaypee Brothers; 2009. p. 188–207.

NCCN Guidelines for Hepatobiliary Cancers. Available at: http://www.nccn.org/professionals/physician_gls/PDF/hepatobiliary.pdf. Accessed 5 June 2009.

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Shukla PJ, Barreto G, Neve R, et al. Can we do better than incidental gallbladder cancer? Hepatogastroenterology. 2007;54:2184–5.PubMed

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Kiran RP, Pokala N, Dudrick SJ. Incidence pattern and survival for gallbladder cancer over three decades—an analysis of 10301 patients. Ann Surg Oncol. 2007;14:827–32.PubMedCrossRef

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Shukla PJ, Barreto SG, Arya S, et al. Does PET-CT scan have a role prior to radical re-resection for incidental gallbladder cancer. HPB (Oxford) . 2008;10:439–45.

Title: Gallbladder Cancer: We Need to Do Better!
Authors: Parul J. Shukla, MBBS, MS, FRCS
Savio G. Barreto, MBBS, MS
Publication date: 01-08-2009
Publisher: Springer-Verlag
Published in: Annals of Surgical Oncology / Issue 8/2009
Print ISSN: 1068-9265
Electronic ISSN: 1534-4681
DOI: https://doi.org/10.1245/s10434-009-0541-2

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Gallbladder Cancer: We Need to Do Better!

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