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01-10-2013 | Hot Topic

Fundamentals and Potential of Magnetic Particle Imaging

Authors: Robert L. Duschka, Julian Haegele, Nikolaos Panagiotopoulos, Hanne Wojtczyk, Joerg Barkhausen, Florian M. Vogt, Thorsten M. Buzug, Kerstin Lüdtke-Buzug

Published in: Current Cardiovascular Imaging Reports | Issue 5/2013

Abstract

Cardiovascular interventions are standard treatment for numerous cardiovascular conditions and require high fidelity imaging tools to accurately visualize both vessels and interventional devices. Currently, digital subtraction angiography (DSA) is the standard method for peripheral arterial angiography. Magnetic particle imaging (MPI) is a new imaging modality, free of ionizing radiation, that utilizes static and oscillating magnetic fields to provide high temporal resolution, sub-millimeter spatial resolution images and high sensitivity. Superparamagnetic iron oxide nanoparticles (SPIOs) are used as tracers in MPI and signals are based on non-linear magnetization characteristics of those SPIOs. Regarding the magnetic moment of used tracers in MPI imaging is much faster in MPI, compared to imaging in CT and MRI. This makes MPI also very attractive for cardiovascular imaging and cardiovascular interventions. First in vivo visualization of a beating mouse heart demonstrated the feasibility of the visualization of the cardiovascular system by MPI. Different scanner designs and acquisition methods have already emerged addressing the requirements of cardiovascular interventions. Early studies have demonstrated MPI as an interesting and promising cardiovascular imaging modality. Technical improvement in hardware MPI imaging systems are currently being addressed in ongoing research which will facilitate former image acquisition with higher resolution in larger animals and/or human.

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Title: Fundamentals and Potential of Magnetic Particle Imaging
Authors: Robert L. Duschka
Julian Haegele
Nikolaos Panagiotopoulos
Hanne Wojtczyk
Joerg Barkhausen
Florian M. Vogt
Thorsten M. Buzug
Kerstin Lüdtke-Buzug
Publication date: 01-10-2013
Publisher: Springer US
Published in: Current Cardiovascular Imaging Reports / Issue 5/2013
Print ISSN: 1941-9066
Electronic ISSN: 1941-9074
DOI: https://doi.org/10.1007/s12410-013-9217-1

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