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Journal of Assisted Reproduction and Genetics

Published in:

01-07-2011 | Assisted Reproduction Technologies

Frozen-thawed embryo transfer cycles: clinical outcomes of single and double blastocyst transfers

Authors: Inna Berin, Sarah T. McLellan, Eric A. Macklin, Thomas L. Toth, Diane L. Wright

Published in: Journal of Assisted Reproduction and Genetics | Issue 7/2011

Abstract

Purpose

To evaluate clinical outcomes of frozen-thawed embryo transfer cycles when one or two blastocysts are transferred.

Methods

Retrospective chart review

Results

Two hundred forty-three frozen blastocyst transfer (FBT) cycles were analyzed. Clinical pregnancy rate (50.4% vs. 34.7%), live birth rate (45.8% vs. 30.6%), and twin live birth rate (19.3% vs. 0) were significantly higher in the double versus single FBT group, respectively (p < 0.05). Prior fresh cycle success with same-cohort embryos did not predict outcome of FBT cycle. When the fresh cycle was unsuccessful, there still was a significant increase in twinning when two frozen-thawed blastocysts were transferred.

Conclusions

Transferring two blastocysts during an FBT cycle resulted in higher live birth and twin live birth rates. Single FBT provided acceptable pregnancy rates for couples seeking to avoid a multiple pregnancy or for those having a single blastocyst stored. Interestingly, the outcome of fresh cycle with same-cohort embryos did not influence the outcome of frozen-thawed cycle.

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Title: Frozen-thawed embryo transfer cycles: clinical outcomes of single and double blastocyst transfers
Authors: Inna Berin
Sarah T. McLellan
Eric A. Macklin
Thomas L. Toth
Diane L. Wright
Publication date: 01-07-2011
Publisher: Springer US
Published in: Journal of Assisted Reproduction and Genetics / Issue 7/2011
Print ISSN: 1058-0468
Electronic ISSN: 1573-7330
DOI: https://doi.org/10.1007/s10815-011-9551-7

At a glance: The STEP trials

Springer Medicine

Frozen-thawed embryo transfer cycles: clinical outcomes of single and double blastocyst transfers

Abstract

Purpose

Methods

Results

Conclusions

At a glance: The STEP trials

Springer Medicine

Abstract

Purpose

Methods

Results

Conclusions

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