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Published in: Abdominal Radiology 3/2014

01-06-2014

Frequency and clinical relevance of PET/CT incidentalomas

Authors: William E. Schaaf Jr., Zeal Patel, Michele Retrouvey, Tina D. Cunningham, Lester S. Johnson

Published in: Abdominal Radiology | Issue 3/2014

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Abstract

Rationale and objectives

To assess the frequency of clinically significant incidental CT findings on PET/CT.

Materials and methods

Reports of 345 cases of baseline standard skull base to thighs PET/CT exams done over the course of a 6 month period at an outpatient facility affiliated with a large tertiary care level 1 trauma medical center were retrospectively reviewed. Incidental CT findings were assigned a level of clinical significance on a scale of 1–5, from doubtful significance to very significant. CT findings already known from prior CT reports were not included. CT findings corresponding to PET findings were also excluded. A score of 3 or greater was considered significant and reportable.

Results

Out of 345 cases, 171 (50%) had a least one CT finding rated at or above a score of 3 on our scale of significance, while 96 (28%) were found to have at least one CT finding with score at or above 4, and 25 cases (7%) showed at least one CT finding rated 5.

Conclusion

A substantial percentage of baseline PET/CT studies contain previously undiagnosed, significant incidental findings on the CT images.
Literature
1.
2.
go back to reference Townsend DW, Carney JP, Yap JT, Hall NC (2004) PET/CT today and tomorrow. J Nucl Med 45(Suppl 1):4S–14SPubMed Townsend DW, Carney JP, Yap JT, Hall NC (2004) PET/CT today and tomorrow. J Nucl Med 45(Suppl 1):4S–14SPubMed
3.
go back to reference Bar-Shalom R, Yefremov N, Guralnik L, et al. (2003) Clinical performance of PET/CT in evaluation of cancer: additional value for diagnostic imaging and patient management. J Nucl Med 44:1200–1209PubMed Bar-Shalom R, Yefremov N, Guralnik L, et al. (2003) Clinical performance of PET/CT in evaluation of cancer: additional value for diagnostic imaging and patient management. J Nucl Med 44:1200–1209PubMed
4.
go back to reference Buck AK, Herrmann K, Stargardt T, et al. (2010) Economic evaluation of PET and PET/CT in oncology: evidence and methodologic approaches. J Nucl Med Technol 38:6–17PubMedCrossRef Buck AK, Herrmann K, Stargardt T, et al. (2010) Economic evaluation of PET and PET/CT in oncology: evidence and methodologic approaches. J Nucl Med Technol 38:6–17PubMedCrossRef
5.
go back to reference Berland LL, Silverman SG, Gore RM, et al. (2010) Managing incidental findings on abdominal CT: white paper of the ACR incidental findings committee. J Am Coll Radiol 7:754–773PubMedCrossRef Berland LL, Silverman SG, Gore RM, et al. (2010) Managing incidental findings on abdominal CT: white paper of the ACR incidental findings committee. J Am Coll Radiol 7:754–773PubMedCrossRef
6.
go back to reference Sgourakis G, Lanitis S, Korontzi M, et al. (2011) Incidental findings in focused assessment with sonography for trauma in hemodynamically stable blunt trauma patients: speaking about cost to benefit. J Trauma 71:E123–E127PubMedCrossRef Sgourakis G, Lanitis S, Korontzi M, et al. (2011) Incidental findings in focused assessment with sonography for trauma in hemodynamically stable blunt trauma patients: speaking about cost to benefit. J Trauma 71:E123–E127PubMedCrossRef
7.
go back to reference van Vugt R, Dekker HM, Deunk J, et al. (2011) Incidental findings on routine thoracoabdominal computed tomography in blunt trauma patients. J Trauma van Vugt R, Dekker HM, Deunk J, et al. (2011) Incidental findings on routine thoracoabdominal computed tomography in blunt trauma patients. J Trauma
8.
go back to reference Orme NM, Fletcher JG, Siddiki HA, et al. (2010) Incidental findings in imaging research: evaluating incidence, benefit, and burden. Arch Intern Med 170:1525–1532PubMedCentralPubMedCrossRef Orme NM, Fletcher JG, Siddiki HA, et al. (2010) Incidental findings in imaging research: evaluating incidence, benefit, and burden. Arch Intern Med 170:1525–1532PubMedCentralPubMedCrossRef
9.
go back to reference Apfaltrer P, Schymik G, Reimer P, et al. (2012) Aortoiliac CT angiography for planning transcutaneous aortic valve implantation: aortic root anatomy and frequency of clinically significant incidental findings. AJR Am J Roentgenol 198:939–945PubMedCrossRef Apfaltrer P, Schymik G, Reimer P, et al. (2012) Aortoiliac CT angiography for planning transcutaneous aortic valve implantation: aortic root anatomy and frequency of clinically significant incidental findings. AJR Am J Roentgenol 198:939–945PubMedCrossRef
10.
go back to reference Lieberman DA (2009) Clinical practice. Screening for colorectal cancer. N Engl J Med 361:1179–1187PubMedCrossRef Lieberman DA (2009) Clinical practice. Screening for colorectal cancer. N Engl J Med 361:1179–1187PubMedCrossRef
11.
go back to reference Cohade C, Osman M, Nakamoto Y, et al. (2003) Initial experience with oral contrast in PET/CT: phantom and clinical studies. J Nucl Med 44:412–416PubMed Cohade C, Osman M, Nakamoto Y, et al. (2003) Initial experience with oral contrast in PET/CT: phantom and clinical studies. J Nucl Med 44:412–416PubMed
Metadata
Title
Frequency and clinical relevance of PET/CT incidentalomas
Authors
William E. Schaaf Jr.
Zeal Patel
Michele Retrouvey
Tina D. Cunningham
Lester S. Johnson
Publication date
01-06-2014
Publisher
Springer US
Published in
Abdominal Radiology / Issue 3/2014
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-014-0086-0

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