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Clinical Journal of Gastroenterology
Published in: Clinical Journal of Gastroenterology 3/2020

01-06-2020 | Foreign Body Aspiration | Case Report

Carcinoma in situ of the pancreas with pancreatic duct stricture persistent for 4 years diagnosed by serial pancreatic juice aspiration cytologic examination (SPACE)

Authors: Sawako Kuruma, Masataka Kikuyama, Kazuro Chiba, Kensuke Yoshimoto, Terumi Kamisawa, Goro Honda, Shinichiro Horiguchi, Jun Nakahodo

Published in: Clinical Journal of Gastroenterology | Issue 3/2020

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Abstract

Serial pancreatic juice aspiration cytologic examination (SPACE) by nasopancreatic tube placement can give us an opportunity to diagnose early-stage pancreatic cancer with higher sensitivity and specificity compared with conventional pancreatic cytology by one-time pancreatic juice aspiration or pancreatic duct brushing. We performed SPACE in a patient with persistent pancreatic duct stricture (PDS) with gradually advancing pancreatic parenchyma atrophy (PPA) in the pancreas tail. The result of SPACE was suggestive of pancreatic carcinoma, and distal pancreatectomy was performed. Histopathological examination of the resected specimen revealed carcinoma in situ of the pancreas. The present case could indicate that any PDS becomes a candidate for SPACE especially in a patient with PPA, although the PDS remains unchanged for a long period.
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Metadata
Title
Carcinoma in situ of the pancreas with pancreatic duct stricture persistent for 4 years diagnosed by serial pancreatic juice aspiration cytologic examination (SPACE)
Authors
Sawako Kuruma
Masataka Kikuyama
Kazuro Chiba
Kensuke Yoshimoto
Terumi Kamisawa
Goro Honda
Shinichiro Horiguchi
Jun Nakahodo
Publication date
01-06-2020
Publisher
Springer Singapore
Published in
Clinical Journal of Gastroenterology / Issue 3/2020
Print ISSN: 1865-7257
Electronic ISSN: 1865-7265
DOI
https://doi.org/10.1007/s12328-019-01065-8

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