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Current Allergy and Asthma Reports
Published in: Current Allergy and Asthma Reports 10/2023

Open Access 04-09-2023 | Food Allergy

Allergen Stability in Food Allergy: A Clinician’s Perspective

Authors: Larissa Koidl, Salvatore Alessio Gentile, Eva Untersmayr

Published in: Current Allergy and Asthma Reports | Issue 10/2023

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Abstract

Purpose of Review

The globally rising food allergy prevalence is associated with the urgent need for new disease prevention methods, efficient treatment, and reliable risk assessment methods for characterization of food allergens. Due to inter-individual variations in the digestive system, food allergens are degraded to a different extent in each person. Food processing also influences allergen digestion.

Recent Findings

In this review, we provide an overview of the digestive system with focus on relevance for food allergy. Main food proteins causing allergic reactions are evaluated, and the combined role of food processing and digestion for allergen stability is highlighted. Finally, clinical implications of this knowledge are discussed.

Summary

Recent literature shows that allergen digestibility is dependent on food processing, digestive conditions, and food matrix. Digestion affects proteins allergenicity. It is currently not possible to predict the immunogenicity of allergens solely based on protein stability.
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Metadata
Title
Allergen Stability in Food Allergy: A Clinician’s Perspective
Authors
Larissa Koidl
Salvatore Alessio Gentile
Eva Untersmayr
Publication date
04-09-2023
Publisher
Springer US
Keyword
Food Allergy
Published in
Current Allergy and Asthma Reports / Issue 10/2023
Print ISSN: 1529-7322
Electronic ISSN: 1534-6315
DOI
https://doi.org/10.1007/s11882-023-01107-9

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