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Clinical and Translational Allergy
Published in: Clinical and Translational Allergy 1/2015

Open Access 01-12-2015 | Research

Food allergy in the Netherlands: differences in clinical severity, causative foods, sensitization and DBPCFC between community and outpatients

Authors: Thuy-My Le, Els van Hoffen, Ischa Kummeling, James Potts, Barbara K Ballmer-Weber, Carla AFM Bruijnzeel-Koomen, Ans FM Lebens, Jonas Lidholm, Titia M Lindner, Alan Mackie, EN Clare Mills, Ronald van Ree, Stefan Vieths, Montserrat Fernández-Rivas, Peter G Burney, André C Knulst

Published in: Clinical and Translational Allergy | Issue 1/2015

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Abstract

Background

It is unknown whether food allergy (FA) in an unselected population is comparable to those from an outpatient clinic population.

Objective

To discover if FA in a random sample from the Dutch community is comparable to that of outpatients.

Methods

This study was part of the Europrevall-project. A random sample of 6600 adults received a questionnaire. Those with symptoms to one of 24 defined priority foods were tested for sIgE. Participants with a positive case history and elevated sIgE were evaluated by double-blind placebo-controlled food challenge (DBPCFC). Outpatients with a suspicion of FA were evaluated by questionnaire, sIgE and DBPCFC.

Results

In the community, severe symptoms were reported less often than in outpatients (39.3% vs. 54.3%). Participants in the community were less commonly sensitized to any of the foods. When selecting only those with a probable FA (i.e. symptoms of priority food and elevation of sIgE to the respective food), no major differences were observed with respect to severity, causative foods, sensitization and DBPCFC between the groups.

Conclusion

In the Netherlands, there are large differences in self-reported FA between community and outpatients. However, Dutch community and outpatients with a probable FA do not differ with respect to severity, causative foods, sensitization and DBPCFC-outcome.
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Metadata
Title
Food allergy in the Netherlands: differences in clinical severity, causative foods, sensitization and DBPCFC between community and outpatients
Authors
Thuy-My Le
Els van Hoffen
Ischa Kummeling
James Potts
Barbara K Ballmer-Weber
Carla AFM Bruijnzeel-Koomen
Ans FM Lebens
Jonas Lidholm
Titia M Lindner
Alan Mackie
EN Clare Mills
Ronald van Ree
Stefan Vieths
Montserrat Fernández-Rivas
Peter G Burney
André C Knulst
Publication date
01-12-2015
Publisher
BioMed Central
Published in
Clinical and Translational Allergy / Issue 1/2015
Electronic ISSN: 2045-7022
DOI
https://doi.org/10.1186/s13601-015-0051-1

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