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Published in: BMC Urology 1/2009

Open Access 01-12-2009 | Debate

Focal therapy for prostate cancer: revolution or evolution?

Authors: Ryan Turpen, Charles J Rosser

Published in: BMC Urology | Issue 1/2009

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Abstract

The face of prostate cancer has been dramatically changed since the late 1980s when PSA was introduced as a clinical screening tool. More men are diagnosed with small foci of cancers instead of the advanced disease evident prior to PSA screening. Treatment options for these smaller tumors consist of expectant management, radiation therapy (brachytherapy and external beam radiotherapy) and surgery (cryosurgical ablation and radical prostatectomy). In the highly select patient, cancer specific survival employing any of these treatment options is excellent, however morbidity from these interventions are significant. Thus, the idea of treating only the cancer within the prostate and sparing the non-cancerous tissue in the prostate is quite appealing, yet controversial. Moving forward if we are to embrace the focal treatment of prostate cancer we must: be able to accurately identify index lesions within the prostate, image cancers within the prostate and methodically study the litany of focal therapeutic options available.
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Metadata
Title
Focal therapy for prostate cancer: revolution or evolution?
Authors
Ryan Turpen
Charles J Rosser
Publication date
01-12-2009
Publisher
BioMed Central
Published in
BMC Urology / Issue 1/2009
Electronic ISSN: 1471-2490
DOI
https://doi.org/10.1186/1471-2490-9-2

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