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BMC Pregnancy and Childbirth

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Open Access 01-12-2024 | Fetal Magnetic Resonance Imaging | Case Report

A case report of single umbilical artery combined with fetal bladder exstrophy in singleton pregnancy and related literature review

Authors: Jun Zhan, Fenglin Jia, Qianqian Gao, Xue Xiao

Published in: BMC Pregnancy and Childbirth | Issue 1/2024

Abstract

Background

According to prenatal ultrasonographic studies, single umbilical artery may be present alone or in association with other fetal abnormalities. So far, the exact pathogenesis of bladder exstrophy is unclear. Some scholars believe that bladder exstrophy and cloacal exstrophy should be regarded as a disease spectrum to explore their pathogenesis. If bladder exstrophy and cloacal exstrophy are regarded as the same disease spectrum, then we can speculate that the single umbilical artery should have the probability of being accompanied by bladder exstrophy at the same time.

Case presentation

For the first time, we report a rare case of fetal bladder exstrophy with single umbilical artery in single pregnancy. This patient underwent targeted color Doppler ultrasound at 26 weeks of pregnancy which first suspected bladder exstrophy with single umbilical artery and fetal MRI for diagnosis at 38 + 3 weeks of pregnancy which confirmed the suspicion. After the diagnosis was confirmed, the patient was scheduled for a multidisciplinary discussion. Ultimately the patient opted for induced fetal demise at 38 + 5 weeks of pregnancy and the physical appearance of the fetal demise affirmed previous ultrasound and MRI examination results.

Conclusions

Our report is the first finding of single umbilical artery combined with bladder exstrophy in a singleton pregnancy. Accordingly, our case enhances the evidence that cloacal exstrophy and bladder exstrophy should be treated as the same disease spectrum. In addition, we conducted a literature review on the diagnostic progress of single umbilical artery combined with bladder exstrophy, hoping to provide useful references for the diagnosis of this disease.

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Title: A case report of single umbilical artery combined with fetal bladder exstrophy in singleton pregnancy and related literature review
Authors: Jun Zhan
Fenglin Jia
Qianqian Gao
Xue Xiao
Publication date: 01-12-2024
Publisher: BioMed Central
Keyword: Fetal Magnetic Resonance Imaging
Published in: BMC Pregnancy and Childbirth / Issue 1/2024
Electronic ISSN: 1471-2393
DOI: https://doi.org/10.1186/s12884-024-06318-0

Keynote webinar | Spotlight on medication adherence

Springer Medicine

A case report of single umbilical artery combined with fetal bladder exstrophy in singleton pregnancy and related literature review

Abstract

Background

Case presentation

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Background

Case presentation

Conclusions

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