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Archives of Public Health
Published in: Archives of Public Health 1/2020

Open Access 01-12-2020 | Fertility | Systematic review

Fertility desire and associated factors among people living with HIV in Ethiopia: a systematic review and meta-analysis

Authors: Getu Mosisa, Reta Tsegaye, Bizuneh Wakuma, Diriba Mulisa, Werku Etefa, Muktar Abadiga, Ginenus Fekadu, Adugna Oluma, Ebisa Turi

Published in: Archives of Public Health | Issue 1/2020

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Abstract

Background

Increased Anti-Retroviral Therapy (ART) coverage improves health status and the survival of people living with Human Immunodeficiency Virus (HIV) as a result, reproductive health needs of the clients are increased. As part of continuum HIV care, understanding fertility desire and reproductive health care needs of HIV positive peoples will play paramount role in planning and delivering appropriate health services. The finding of studies conducted on the fertility desire and associated factors among People Living with HIV in Ethiopia presented inconclusive. Therefore, this study aimed to assess the pooled prevalence of fertility desire and associated factors among people living with HIV in Ethiopia.

Methods

A total of 26 studies conducted in Ethiopia were included in this Meta-analysis. Pub Med, HINARI, Google scholar and Google data bases were searched. Data from the included articles were extracted using a standardized data extraction tool. The included studies were analyzed using a random effects meta-analysis model. Analysis was done Using STATA version 14 statistical software. Heterogeneity was assessed statistically using the standard Chi-square, I2. The association between fertility desire and factors were examined using a random effects model.

Result

In this meta-analysis, the pooled prevalence of fertility desire in Ethiopia is 42.21% (95%CI 39.18, 45.25). Fertility desire is significantly associated with sex: being female (OR = 0.71,95%CI 0.57,0.86), partners desire (OR = 16.8, 95% CI: 9.45, 29.88), not having child (OR = 5.46 95%CI 4.24, 7.040), age < 30(OR = 2.34, 95%CI 2.10, 2.60), formal education (OR = 1.31 95%CI 1.09, 1.59)). However, use of family planning, residence, and Knowledge on Prevention of Mother to Child Transmission and disclosure status didn’t show association with fertility desire.

Conclusion

In this finding, significant people of living with HIV have a desire to have a child. The finding showed the need to strengthen fertility desire and reproductive health care needs of HIV positive peoples. Therefore, strengthening the integration of fertility related issues with HIV continuum care will play a paramount role in averting risky sexual behaviors and Prevention of Mother to Child Transmission among peoples on ART.
Literature
1.
UNAIDS GH. AIDS statistics—2019 fact sheet; 2019.
2.
Ethiopia F. Country Progress report on the HIV response; 2014.
3.
Wilcher R, Petruney T, Reynolds H, Cates W. From effectiveness to impact: contraception as an HIV prevention intervention. Sexually Transmitted Infect. 2008;84(Suppl 2):ii54–60.CrossRef
4.
5.
Mirkuzie AH. Implementation and outcomes of guideline revisions for the prevention of mother-to-child HIV transmission in mother support Programme, Addis Ababa, Ethiopia. PloS one. 2018;13(6):e0198438.PubMedPubMedCentralCrossRef
6.
Federal Ministry of Health. National comprehensive PMTCT/MNCH/RH training package guideline reference manual. Addis Ababa: FMOH; 2013.
7.
Tolossa T, Mulisa D, Fetensa G, Fekadu G. Magnitude and factors associated with lost to follow-up among women under option B+ PMTCT program at East Wollega public health facilities, Western Ethiopia. Int J Africa Nursing Sciences. 2020;100212.
8.
9.
10.
11.
Boonstra H. Meeting the sexual and reproductive health needs of people living with HIV. Issues in Brief (Alan Guttmacher Institute). 2006(6):1–4.
12.
Ayieko J, Ti A, Hagey J, Akama E, Bukusi EA, Cohen CR, et al. HIV status and treatment influence on fertility desires among women newly becoming eligible for antiretroviral therapy in western Kenya: insights from a qualitative study. Reprod Health. 2017;14(1):93.PubMedPubMedCentralCrossRef
13.
Mujumdar V, Berman D, Schafer KR. Reproduction and fertility beliefs, perceptions, and attitudes in people living with HIV. AIDS Res Treatment. 2018;2018.
14.
Mmbaga EJ, Leyna GH, Ezekiel MJ, Kakoko DC. Fertility desire and intention of people living with HIV/AIDS in Tanzania: a call for restructuring care and treatment services. BMC Public Health. 2013;13(1):86.PubMedPubMedCentralCrossRef
15.
Wanyenze RK, Wagner GJ, Tumwesigye NM, Nannyonga M, Wabwire-Mangen F, Kamya MR. Fertility and contraceptive decision-making and support for HIV infected individuals: client and provider experiences and perceptions at two HIV clinics in Uganda. BMC Public Health. 2013;13(1):98.PubMedPubMedCentralCrossRef
16.
Jose H, Madi D, Chowta N, Ramapuram J, Bhaskaran U, Achappa B, et al. Fertility desires and intentions among people living with HIV/AIDS (PLWHA) in southern India. J Clin Diagnostic Res. 2016;10(6):OC19–22.
17.
Pottinger AM, Carroll K. Reproductive needs of PLHIV in Jamaica: relationship between fertility desire, motives and depression. J Reprod Infant Psychology. 2020;38(1):38–48.CrossRef
18.
Kaoje A, Ibrahim M, Njoku C, Gusau G, Saad A, Raji M. Predictors of fertility desire among people living with HIV attending anti-retroviral clinic in a tertiary health facility in Sokoto, Northern Nigeria. Sahel Medical Journal. 2015;18(1):14.CrossRef
19.
Institute JB. Meta-analysis of statistics: assessment and review instrument (JBI MASTARI). Adelaide: Joanna Briggs Institute. 2006;20032007.
20.
Ahmed M, Kahsay A, Miruts G, Berhe K. Magnitude and factors affecting the fertility desire of people living with HIV infection in ethiopia-a cross sectional study. J AIDS Clinical Res. 2014;5:9.CrossRef
21.
Haile F, Isahak N, Dessie A. Fertility desire and associated factors among people living with HIV on ART. Harari Regional State, Eastern Ethiopia. J Trop Dis. 2014;2:3.
22.
Gayesa RT, Mengistu D, Moorhead C. Desire for fertility and associated factors among people living with hiv/aids (plwha) in selected antiretroviral therapy (art) clinics of horro guduru wollega zone, north west oromia, Ethiopia-a cross sectional study. Int J Pharmaceutical Sci Res. 2013;4(6):2312.
23.
Abebe M, Endazenaw GJASRJfE, Technology,, Sciences. Fertility Intention and Family Planning use Among People Living with HIV/AIDS (PLHIV) on Follow up Care Western Shoa Zone, Anti Retroviral Treatment (ART) Unit, Oromia, Ethiopia 2015;12(1):75–91.
24.
Kebede Y, Tola G, Habtamu A. Understanding the socio-psychological, Demographic, obstetric and treatment-status aspects of fertility desire among anti-retroviral treatment clients, Dodota District, Oromia, Ethiopia. Epidemiology (Sunnyvale). 2019;9(373):2161–1165.1000373.
25.
Asfaw HM, Gashe FE. Fertility intentions among HIV positive women aged 18-49 years in Addis Ababa Ethiopia: a cross sectional study. Reprod Health. 2014;11:36.PubMedPubMedCentralCrossRef
26.
Regassa T, Fantahun MJS. Fertility desire and reproductive health care needs of men and women living with HIV/AIDS in Nekemte, East Wollega, Ethiopia. Technology and Arts Research J. 2012;1(3):31–8.CrossRef
27.
Abebe M, Addissie A, Regassa TJS. Fertility desire and contraceptive utilization among people living with HIV/AIDS on ART in Hosanna Town, Southern Ethiopia. Technology and Arts Research J. 2012;1(4):38–46.CrossRef
28.
Melka AS, Wordofa MA, Wossen BA. Determinants of fertility intention among women living with hiv in western Ethiopia: implications for service delivery. Afr J Reprod Health. 2014;18(4):54–60.
29.
Mohammed A. Assessment of pregnancy and fertility desire among HIV positive women clients who were attending ART clinics in North Gondar administrative Zone; 2010.
30.
Koyra HC, Biramo YB, Tufa EGJAJPHR. Fertility desire and associated factors among people living with HIV/AIDs at selected health facilities of Wolaita Zone. Southern Ethiopia: cross-sectional study. 2017;5(3):79–88.
31.
Desta A. The desire to have children: is Pmtct an opportunity for Hiv positive people? A cross sectional study in Mekelle health institutions, Tigray/Ethiopia, 2009: Addis Ababa university; 2009.
32.
Alemayehu B, Aregay AJJoA, research H. Desire to procreate among people living with HIV/AIDS: Determinants in Ethiopia: a cross-sectional study 2012;4(5):128–135.
33.
Hassen K, Abdullahi MJGJoMR. Assessment of Sexual Behavior, Unmet Reproductive Health Needs and Fertility Intention of People Living with HIV/AIDS, Jimma, South West of Ethiopia. 2013.
34.
Mokwena K, Bogale YRJSAFP. Fertility intention and use of contraception among women living with the human immunodeficiency virus in Oromia region. Ethiopia. 2017;59(1):46–51.
35.
Adilo TM, Wordofa HM. Prevalence of fertility desire and its associated factors among 15- to 49-year-old people living with HIV/AIDS in Addis Ababa, Ethiopia: a cross-sectional study design. HIV AIDS (Auckl). 2017;9:167–76.
36.
Mekonnen B, Minyihun A. Fertility Desire And Associated Factors Among HIV Positive Women Attending ART Clinics In Amhara Region Referral Hospitals In Northwest Ethiopia, 2017. Hiv/aids (Auckland, NZ). 2019;11:247.
37.
Assefa W. Fertility desire and associated factors among adult on anti-retroviral therapy users in bale ZONE HOSPITALS. SOUTH EAST ETHIOPIA: OROMIA REGIONAL STATE; 2017.
38.
Tadesse L. Assessment of fertility desire and family planning utilization among HIV positive people who are on antiretroviral treatment, Asella hospital, Arsi Zone, Oromia region, 2011: Addis Abeba university; 2011.
39.
Demissie DB, Tebeje B, Tesfaye T. Fertility desire and associated factors among people living with HIV attending antiretroviral therapy clinic in Ethiopia. BMC Pregnancy Childbirth. 2014;14:382.PubMedPubMedCentralCrossRef
40.
Melaku YA, Zeleke EG, Kinsman J, Abraha AK. Fertility desire among HIV-positive women in Tigray region, Ethiopia: implications for the provision of reproductive health and prevention of mother-to-child HIV transmission services. BMC Womens Health. 2014;14:137.PubMedPubMedCentralCrossRef
41.
Abbawa F, Awoke W, Alemu Y. Fertility desire and associated factors among clients on highly active antiretroviral treatment at finoteselam hospital Northwest Ethiopia: a cross sectional study. Reprod Health. 2015;12:69.PubMedPubMedCentralCrossRef
42.
Shiferaw T, Kiros G, Birhanu Z, Gebreyesus H, Berhe T, Teweldemedhin M. Fertility desire and associated factors among women on the reproductive age group of antiretroviral treatment users in Jimma town, South West Ethiopia. BMC Res Notes. 2019;12(1):158.PubMedPubMedCentralCrossRef
43.
Tamene W, Fantahun M. Fertility desire and family-planning demand among HIV-positive women and men undergoing antiretroviral treatment in Addis Ababa. Ethiopia Afr J AIDS Res. 2007;6(3):223–7.PubMedCrossRef
44.
Tesfaye L, Admassu M, Getachew A, Sharma HRJVC, Studies Y. Fertility desires and family planning demand among HIV-positive clients in follow-up care at antiretroviral treatment unit in Gondar university hospital. Ethiopia. 2012;7(1):20–35.
45.
Gossa T. Fertility needs assessment among people living with HIV/AIDS in four regional Hospitals. Addis Ababa: Addis Ababa University; 2010.
46.
Demographic E. Health survey: Addis Ababa, vol. 2011. Ethiopia and Calverton, Maryland: Central statistics agency and ORC macro; 2011.
47.
Nóbrega AA, Oliveira FA, Galvão MT, Mota RS, Barbosa RM, Dourado I, et al. Desire for a child among women living with HIV/AIDS in Northeast Brazil. AIDS Patient Care STDs. 2007;21(4):261–7.PubMedCrossRef
48.
Loutfy MR, Hart TA, Mohammed SS, Su D, Ralph ED, Walmsley SL, et al. Fertility desires and intentions of HIV-positive women of reproductive age in Ontario, Canada: a cross-sectional study. PLoS One. 2009;4(12):e7925.PubMedPubMedCentralCrossRef
49.
Kawale P, Mindry D, Stramotas S, Chilikoh P, Phoya A, Henry K, et al. Factors associated with desire for children among HIV-infected women and men: a quantitative and qualitative analysis from Malawi and implications for the delivery of safer conception counseling. AIDS Care. 2014;26(6):769–76.PubMedCrossRef
50.
Myer L, Morroni C, Rebe K. Prevalence and determinants of fertility intentions of HIV-infected women and men receiving antiretroviral therapy in South Africa. AIDS Patient Care STDs. 2007;21(4):278–85.PubMedCrossRef
51.
Nakayiwa S, Abang B, Packel L, Lifshay J, Purcell DW, King R, et al. Desire for children and pregnancy risk behavior among HIV-infected men and women in Uganda. AIDS Behav. 2006;10(1):95.CrossRef
52.
Yeatman S, Eaton JW, Beckles Z, Benton L, Gregson S, Zaba B. Impact of ART on the fertility of HIV-positive women in sub-Saharan Africa. Tropical Med Int Health. 2016;21(9):1071–85.CrossRef
53.
Cooper D, Mantell JE, Moodley J, Mall S. The HIV epidemic and sexual and reproductive health policy integration: views of South African policymakers. BMC Public Health. 2015;15(1):1–9.CrossRef
54.
Cernigliaro D, Barrington C, Perez M, Donastorg Y, Kerrigan D. Factors related to fertility desire among female sex workers living with HIV in the Dominican Republic. BMC Womens Health. 2018;18(1):117.PubMedPubMedCentralCrossRef
55.
56.
Gutin SA, Namusoke F, Shade SB, Mirembe F. Fertility desires and intentions among HIV-positive women during the post-natal period in Uganda. Afr J Reprod Health. 2014;18(3):67–77.PubMed
Metadata
Title
Fertility desire and associated factors among people living with HIV in Ethiopia: a systematic review and meta-analysis
Authors
Getu Mosisa
Reta Tsegaye
Bizuneh Wakuma
Diriba Mulisa
Werku Etefa
Muktar Abadiga
Ginenus Fekadu
Adugna Oluma
Ebisa Turi
Publication date
01-12-2020
Publisher
BioMed Central
Published in
Archives of Public Health / Issue 1/2020
Electronic ISSN: 2049-3258
DOI
https://doi.org/10.1186/s13690-020-00504-0

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