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Open Access 01-03-2009 | Clinical Study - Patient Study

Fatigue in low-grade glioma

Authors: Karin Struik, Martin Klein, Jan J. Heimans, Marieke F. Gielissen, Gijs Bleijenberg, Martin J. Taphoorn, Jaap C. Reijneveld, Tjeerd J. Postma

Published in: Journal of Neuro-Oncology | Issue 1/2009

Abstract

The aim of this study was to determine the prevalence and severity of fatigue in long-term survivors with a low-grade glioma (LGG), and to analyze the relationship between fatigue and demographic variables, disease duration, tumor characteristics, former tumor treatment modalities, antiepileptic drug (AED) use, self-reported concentration, motivation, and activity. Fifty-four patients with stable disease (age range, 25–73 years) who were diagnosed and treated more than 8 years ago were included in this study. Fatigue was analyzed with the Checklist Individual Strength (CIS). Thirty-nine percent of the LGG patients were severely fatigued, with older patients being most affected. Severe fatigue was associated with AED use, and with reduced self-reported concentration, motivation, and activity. No relation was found between fatigue and gender, histology, tumor laterality, disease duration, type of neurosurgical intervention and radiation treatment. Fatigue is a severe problem in a large proportion of long-term surviving LGG patients.

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Title: Fatigue in low-grade glioma
Authors: Karin Struik
Martin Klein
Jan J. Heimans
Marieke F. Gielissen
Gijs Bleijenberg
Martin J. Taphoorn
Jaap C. Reijneveld
Tjeerd J. Postma
Publication date: 01-03-2009
Publisher: Springer US
Published in: Journal of Neuro-Oncology / Issue 1/2009
Print ISSN: 0167-594X
Electronic ISSN: 1573-7373
DOI: https://doi.org/10.1007/s11060-008-9738-7

At a glance: The STEP trials

Springer Medicine

Fatigue in low-grade glioma

Abstract

At a glance: The STEP trials

Springer Medicine

Abstract

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