Skip to main content
Top
Published in: Abdominal Radiology 2/2004

01-03-2004 | Original article

Fatal, complete splenic infarction and hepatic infection due to disseminated Trichosporon beigelii infection

Authors: S. G. Viscomi, K. J. Mortelé, V. Cantisani, J. Glickman, S. G. Silverman

Published in: Abdominal Radiology | Issue 2/2004

Login to get access

Abstract

We report on a 56-year-old woman with acute lymphocytic leukemia who presented with right upper quadrant pain, fever, nausea, and vomiting. Laboratory studies confirmed fungemia with Trichosporum beigelii, and contrast-enhanced computed tomography of the abdomen demonstrated numerous low-attenuation liver lesions and a hypodense spleen with capsular enhancement suggestive of complete splenic infarction. Subsequent splenectomy confirmed that the spleen was completely infarcted and infiltrated with Trichosporum. The patient had a difficult postoperative course and died despite aggressive antifungal therapy.
Literature
1.
go back to reference Sklair-Levy, M, Libson, Y, Lossos, IS, Bugomolsky-Yahalom, V 1998Splenic calcifications caused by Trichosporon beigelli infection: CT and ultrasound demonstration.Eur Radiol8922924PubMedCrossRef Sklair-Levy, M, Libson, Y, Lossos, IS, Bugomolsky-Yahalom, V 1998Splenic calcifications caused by Trichosporon beigelli infection: CT and ultrasound demonstration.Eur Radiol8922924PubMedCrossRef
2.
go back to reference Krcmery, V Jr, Mateicka, F, Kunova, A, et al. 1999 Hematogenous trichosporonosis in cancer patients: report of 12 cases including 5 during prophylaxis with itraconazole.Support Care Cancer73943PubMedCrossRef Krcmery, V Jr, Mateicka, F, Kunova, A,  et al. 1999 Hematogenous trichosporonosis in cancer patients: report of 12 cases including 5 during prophylaxis with itraconazole.Support Care Cancer73943PubMedCrossRef
3.
go back to reference Nagai, H, Yamakami, Y, Hashimoto, A, et al. 1999 PCR detection of DNA specific for Trichosporon species in serum of patients with disseminated trichosporonosis.J Clin Microbiol37694699PubMed Nagai, H, Yamakami, Y, Hashimoto, A,  et al. 1999 PCR detection of DNA specific for Trichosporon species in serum of patients with disseminated trichosporonosis.J Clin Microbiol37694699PubMed
4.
go back to reference Yamagata, E, Kamberi, P, Yamakami, Y, et al. 2000 Experimental model of progressive disseminated trichosporonosis in mice with latent trichosporonemia.J Clin Microbiol3832603266PubMed Yamagata, E, Kamberi, P, Yamakami, Y,  et al. 2000 Experimental model of progressive disseminated trichosporonosis in mice with latent trichosporonemia.J Clin Microbiol3832603266PubMed
5.
go back to reference Sidarous, MG, O’Reilly, MV, Cherubin, CE 1994 A case of trichosporon beigelii endocarditis 8 year after aortic valve replacement.Clin Cardiol17215219PubMedCrossRef Sidarous, MG, O’Reilly, MV, Cherubin, CE 1994 A case of trichosporon beigelii endocarditis 8 year after aortic valve replacement.Clin Cardiol17215219PubMedCrossRef
6.
go back to reference Hoy, J, Hsu, KC, Roston, K, et al. 1986 Trichosporon beigelii infection: a review.Rev Infect Dis8959967PubMedCrossRef Hoy, J, Hsu, KC, Roston, K,  et al. 1986 Trichosporon beigelii infection: a review.Rev Infect Dis8959967PubMedCrossRef
7.
go back to reference Walch, TJ, Melcher, GP, Rinaldi, MG, et al. 1990 Trichosporon beigelli, an emerging pathogen resistant to amphotericin B.J Clin Microbiol2816161622 Walch, TJ, Melcher, GP, Rinaldi, MG,  et al. 1990 Trichosporon beigelli, an emerging pathogen resistant to amphotericin B.J Clin Microbiol2816161622
8.
go back to reference Walch, TJ, Newman, KL, Moody, M, et al. 1986 Trichosporonosis in patients with neoplastic disease.Medicine65268279CrossRef Walch, TJ, Newman, KL, Moody, M,  et al. 1986 Trichosporonosis in patients with neoplastic disease.Medicine65268279CrossRef
9.
10.
go back to reference Balcar, I, Seltzer, SE, Davis, S, Geller, S 1984 CT patterns of splenic infarction: a clinical and experimental study.Radiology151723729PubMed Balcar, I, Seltzer, SE, Davis, S, Geller, S 1984 CT patterns of splenic infarction: a clinical and experimental study.Radiology151723729PubMed
11.
12.
go back to reference Freeman, JL, Jafri, SZH, Roberts, JL, et al. 1993 CT of congenital and acquired abnormalities of the spleen.Radiographics13597610PubMed Freeman, JL, Jafri, SZH, Roberts, JL,  et al. 1993 CT of congenital and acquired abnormalities of the spleen.Radiographics13597610PubMed
13.
go back to reference Taylor, AJ, Dodds, WJ, Ericson, SJ, Stewart, ET 1991 CT of acquired abnormalities of the spleen.AJR15712131219PubMed Taylor, AJ, Dodds, WJ, Ericson, SJ, Stewart, ET 1991 CT of acquired abnormalities of the spleen.AJR15712131219PubMed
Metadata
Title
Fatal, complete splenic infarction and hepatic infection due to disseminated Trichosporon beigelii infection
Authors
S. G. Viscomi
K. J. Mortelé
V. Cantisani
J. Glickman
S. G. Silverman
Publication date
01-03-2004
Publisher
Springer-Verlag
Published in
Abdominal Radiology / Issue 2/2004
Print ISSN: 2366-004X
Electronic ISSN: 2366-0058
DOI
https://doi.org/10.1007/s00261-003-0099-6

Other articles of this Issue 2/2004

Abdominal Radiology 2/2004 Go to the issue

Book Reviews

Book reviews

Obesity Clinical Trial Summary

At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.

Developed by: Springer Medicine

Highlights from the ACC 2024 Congress

Year in Review: Pediatric cardiology

Watch Dr. Anne Marie Valente present the last year's highlights in pediatric and congenital heart disease in the official ACC.24 Year in Review session.

Year in Review: Pulmonary vascular disease

The last year's highlights in pulmonary vascular disease are presented by Dr. Jane Leopold in this official video from ACC.24.

Year in Review: Valvular heart disease

Watch Prof. William Zoghbi present the last year's highlights in valvular heart disease from the official ACC.24 Year in Review session.

Year in Review: Heart failure and cardiomyopathies

Watch this official video from ACC.24. Dr. Biykem Bozkurt discuss last year's major advances in heart failure and cardiomyopathies.