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At a glance: The STEP trials

A round-up of the STEP phase 3 clinical trials evaluating semaglutide for weight loss in people with overweight or obesity.
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Sleep and Breathing
Published in: Sleep and Breathing 4/2019

01-12-2019 | Epidemiology • Review

Experimental sleep restriction effect on adult body weight: a meta-analysis

Authors: Haiqing Yu, Jiao Lu, Pengli Jia, Can Liu, Jingmin Cheng

Published in: Sleep and Breathing | Issue 4/2019

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Abstract

Background

Sleep is increasingly recognized as a potential risk for overweight and obesity. Observational studies have shown links between short sleep duration with weight gain. However, the findings from longitudinal studies in adults are conflicting. This review aimed to examine the effectiveness of experimental sleep restriction on adult body weight.

Method

A systematic search was undertaken in MEDLINE, EMBASE, PsycINFO, and CENTRAL (Cochrane center register of controlled trials) to identify experimental studies examining the effectiveness of sleep restriction on body weight, and search period was from January 2005 to June 2018. Meta-analysis was applied by using the random model.

Results

A total of 275 adults from six experimental studies were included. The pooled standard mean difference in body weight and body fat was 0.44 (95% CI − 0.13 to 1.02) (Z = 1.51, p > 0.05) and 0.35 kg (95% CI − 0.19 to 0.88) (Z = 1.27, p > 0.05), respectively. The experimental sleep restriction did not result in significant differences in adult body weight or body fat. Subgroup analysis showed that there were differences in weight gain between genders and races.

Conclusion

The finding from this review cannot support the hypothesis from observational studies that short sleep leads to weight gain.
Appendix
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Metadata
Title
Experimental sleep restriction effect on adult body weight: a meta-analysis
Authors
Haiqing Yu
Jiao Lu
Pengli Jia
Can Liu
Jingmin Cheng
Publication date
01-12-2019
Publisher
Springer International Publishing
Published in
Sleep and Breathing / Issue 4/2019
Print ISSN: 1520-9512
Electronic ISSN: 1522-1709
DOI
https://doi.org/10.1007/s11325-019-01828-0

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