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Published in: BMC Infectious Diseases 1/2018

Open Access 01-12-2018 | Case report

Exceptional association of two species of bacteria causing mediastinitis: Haemophilus influenzae (H. influenzae) and Aggregatibacter aphrophilus (A. aphrophilus)

Authors: Badia Belarj, Souhail Dahraoui, Leila Rar, Noureddine Atmani, Mohammed Frikh, Yassine Ben Lahlou, Adil Maleb, Abdelhay Lemnouer, Mahdi Ait Houssa, Abdelatif Boulahya, Mostafa Elouennass

Published in: BMC Infectious Diseases | Issue 1/2018

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Abstract

Background

Post cardiac surgery mediastinitis is the major infectious complication, despite the development of surgical techniques and the application of strict preventive measures.
The Haemophilus influenzae mediastinitis is very rare. The mediastinitis caused by the association between Haemophilus influenzae and Aggregatibacter aphrophilus has never been described to our knowledge.

Case presentation

We report the case of an exceptional combination of Haemophilus influenzae and Aggregatibacter aphrophilus in a patient operated for single bypass which is complicated by mediastinitis the 10th day after the surgical act.

Conclusion

The conclusion to be drawn from this work is to think in unusual seeds in case of mediastinitis post cardiac surgery for the elaboration of recommendations for antibiotic prophylaxis.
Literature
1.
go back to reference Nguyen D-C, Nguyen H-T. Postoperative mediastinitis: diagnosis and treatment. EMC-Cardiologie Angéiologie. 2005;2:337–43.CrossRef Nguyen D-C, Nguyen H-T. Postoperative mediastinitis: diagnosis and treatment. EMC-Cardiologie Angéiologie. 2005;2:337–43.CrossRef
2.
go back to reference Lepelletier D, Perron S, Michaud JL. Médiastinites après chirurgie cardiaque : incidence, microbiologie et facteurs de risque. Pathologie infectieuse; Antibiotiques. 2005;7:18–22.CrossRef Lepelletier D, Perron S, Michaud JL. Médiastinites après chirurgie cardiaque : incidence, microbiologie et facteurs de risque. Pathologie infectieuse; Antibiotiques. 2005;7:18–22.CrossRef
3.
go back to reference Maleb A, Nya F, Amahzoune B, Lemnouer A, Elouennass M. Postoperative mediastinitis due to Candida tropicalis: first reported case in Morocco. J Mycol Méd. 2014;24(3):225–8.CrossRefPubMed Maleb A, Nya F, Amahzoune B, Lemnouer A, Elouennass M. Postoperative mediastinitis due to Candida tropicalis: first reported case in Morocco. J Mycol Méd. 2014;24(3):225–8.CrossRefPubMed
4.
go back to reference Costache V, Gaudreau G, Houde C, Rodière M, Hacini R, Blin D, Chavanon O. Intérêt de l’association VAC®-thérapie, ostéosynthèse sternale et lambeaux pectoraux d’avancement dans la prise en charge d’une médiastinite postopératoire après chirurgie cardiaque chez une obèse diabétique. Ann Chir Plast Esthét. 2010;55(6):597–602.CrossRefPubMed Costache V, Gaudreau G, Houde C, Rodière M, Hacini R, Blin D, Chavanon O. Intérêt de l’association VAC®-thérapie, ostéosynthèse sternale et lambeaux pectoraux d’avancement dans la prise en charge d’une médiastinite postopératoire après chirurgie cardiaque chez une obèse diabétique. Ann Chir Plast Esthét. 2010;55(6):597–602.CrossRefPubMed
5.
go back to reference Bourigaul LC, Roussel JC, Lasserre C, Leclère B, Corveca S, Pattierb S, Lepoivre T, Baron O, Despins P. Epidemiology and prevention of surgical site infections after cardiac surgery. Med Mal Infect. 2013;43(10):403–9.CrossRef Bourigaul LC, Roussel JC, Lasserre C, Leclère B, Corveca S, Pattierb S, Lepoivre T, Baron O, Despins P. Epidemiology and prevention of surgical site infections after cardiac surgery. Med Mal Infect. 2013;43(10):403–9.CrossRef
6.
go back to reference Lepelletier D, Poupelin L, Corveca S, Bourigault C, Bizouarn P, Blanloeil Y, Reynaud A, Duveau D, Despins P. Risk factors for mortality in patients with mediastinitis after cardiac surgery evaluation. Arch Cardiovasc Dis. 2009;102:119–25.CrossRefPubMed Lepelletier D, Poupelin L, Corveca S, Bourigault C, Bizouarn P, Blanloeil Y, Reynaud A, Duveau D, Despins P. Risk factors for mortality in patients with mediastinitis after cardiac surgery evaluation. Arch Cardiovasc Dis. 2009;102:119–25.CrossRefPubMed
7.
go back to reference Charbonneau H, et al. Mediastinitis due to Gram-negative bacteria is associated with increased mortality. Clin Microbiol Infect. 2014;20:O197–202.CrossRefPubMed Charbonneau H, et al. Mediastinitis due to Gram-negative bacteria is associated with increased mortality. Clin Microbiol Infect. 2014;20:O197–202.CrossRefPubMed
8.
go back to reference Nørskov-Lauritsen N. Classification, identification, and clinical significance of Haemophilus and Aggregatibacter species with host specificity for humans. Clin Microbiol Rev. 2014;27(2):214–40.CrossRefPubMedPubMedCentral Nørskov-Lauritsen N. Classification, identification, and clinical significance of Haemophilus and Aggregatibacter species with host specificity for humans. Clin Microbiol Rev. 2014;27(2):214–40.CrossRefPubMedPubMedCentral
9.
go back to reference David Martin A, Reema H, Dbouk B, Marlene Deleon-Carnes C, del Rio C, Guarner J. Haemophilus influenzae acute endometritis with bacteremia: case report and literature review. Diagn Microbiol Infect Dis. 2013;76(2):235–6.CrossRefPubMed David Martin A, Reema H, Dbouk B, Marlene Deleon-Carnes C, del Rio C, Guarner J. Haemophilus influenzae acute endometritis with bacteremia: case report and literature review. Diagn Microbiol Infect Dis. 2013;76(2):235–6.CrossRefPubMed
10.
go back to reference Rehman SM, et al. Risk factors for mediastinitis following cardiac surgery: the importance of managing obesity. J Hosp Infect. 2014;88:96–102.CrossRefPubMed Rehman SM, et al. Risk factors for mediastinitis following cardiac surgery: the importance of managing obesity. J Hosp Infect. 2014;88:96–102.CrossRefPubMed
11.
go back to reference Durrleman N, El Hamamsy I, Hébert Y, Pellerin M, Carrier M, Perrault LP. Modalités thérapeutique des médiastinites en chirurgie cardiaque. Chir Thor Cardio-Vasc. 2006;10:4–17. Durrleman N, El Hamamsy I, Hébert Y, Pellerin M, Carrier M, Perrault LP. Modalités thérapeutique des médiastinites en chirurgie cardiaque. Chir Thor Cardio-Vasc. 2006;10:4–17.
12.
go back to reference Darras-Joly C, et al. Haemophilus endocarditis: report of 42 casesin adult and review. Clin Infect Dis. 1997;24:1087–94.CrossRefPubMed Darras-Joly C, et al. Haemophilus endocarditis: report of 42 casesin adult and review. Clin Infect Dis. 1997;24:1087–94.CrossRefPubMed
13.
go back to reference Dabernata H, Seguya M, Fauconb G, Delmasa C. Épidémiologie et évaluation de la sensibilité aux antibiotiques de souches d’Haemophilus influenzae isolées en 2004 en France. Med Mal Infect. 2007;37(6):320–32.CrossRef Dabernata H, Seguya M, Fauconb G, Delmasa C. Épidémiologie et évaluation de la sensibilité aux antibiotiques de souches d’Haemophilus influenzae isolées en 2004 en France. Med Mal Infect. 2007;37(6):320–32.CrossRef
14.
go back to reference Lecharny JB, Tapia M, Baudot J, Philip I. Médiastinites après chirurgie cardiaque. Conférences d’actualisation; 2001. p. 677–92. Lecharny JB, Tapia M, Baudot J, Philip I. Médiastinites après chirurgie cardiaque. Conférences d’actualisation; 2001. p. 677–92.
Metadata
Title
Exceptional association of two species of bacteria causing mediastinitis: Haemophilus influenzae (H. influenzae) and Aggregatibacter aphrophilus (A. aphrophilus)
Authors
Badia Belarj
Souhail Dahraoui
Leila Rar
Noureddine Atmani
Mohammed Frikh
Yassine Ben Lahlou
Adil Maleb
Abdelhay Lemnouer
Mahdi Ait Houssa
Abdelatif Boulahya
Mostafa Elouennass
Publication date
01-12-2018
Publisher
BioMed Central
Published in
BMC Infectious Diseases / Issue 1/2018
Electronic ISSN: 1471-2334
DOI
https://doi.org/10.1186/s12879-018-3269-4

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