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Indian Journal of Surgical Oncology
Published in: Indian Journal of Surgical Oncology 3/2021

01-09-2021 | Ewing's Sarcoma | Original Article

Management of Abdominal Ewing’s Sarcoma: A Single Institute Experience

Authors: Ambarish Chatterjee, Shraddha Patkar, Nilendu Purandare, Smruti Mokal, Mahesh Goel

Published in: Indian Journal of Surgical Oncology | Issue 3/2021

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Abstract

Ewing’s sarcoma (ES)/primitive neuroectodermal tumors (PNETs) are a rare group of tumors commonly arising from bones, uncommonly from soft tissues, and rarely from abdomen. The aim of the study was to analyze the outcome (recurrence-free survival[RFS]), patient characteristics, role of FDG-PET (fluorodeoxyglucose positron emission tomography) computerized scan, chemotherapy and radiation, and prognostic factors. We retrospectively studied patients diagnosed with abdominal ES/PNET and treated surgically between June 2005 and November 2019. Ten patients were included in the study, with a median age of 36.5 years (19–46 years). The median follow-up was 25 months (3–178 months). The site of origin was the retroperitoneum, small bowel, and abdominal wall in six, two, and two patients, respectively. 70% of patients were treated with induction chemotherapy. R0 resection was achieved in 90% of patients. With chemotherapy, there was significant reduction in tumor size (p = 0.034) with non-significant reduction in SUV max (p = 0.31). The 1- and 2-year RFS were 88.90% and 76.20%, respectively. Pathological peritoneal metastasis and ability to achieve R0 resection were prognostic factors affecting RFS. These patients must be offered multimodality treatment. Induction chemotherapy significantly reduces the tumor size. Pathological peritoneal metastasis and ability to achieving R0 resection significantly affect survival.
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Metadata
Title
Management of Abdominal Ewing’s Sarcoma: A Single Institute Experience
Authors
Ambarish Chatterjee
Shraddha Patkar
Nilendu Purandare
Smruti Mokal
Mahesh Goel
Publication date
01-09-2021
Publisher
Springer India
Published in
Indian Journal of Surgical Oncology / Issue 3/2021
Print ISSN: 0975-7651
Electronic ISSN: 0976-6952
DOI
https://doi.org/10.1007/s13193-021-01409-2

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