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01-12-2010 | Original Paper

Evaluation of cardiac autonomic functions in patients with ankylosing spondylitis via heart rate recovery and heart rate variability

Authors: Ergun Baris Kaya, Sercan Okutucu, Hakan Aksoy, Ugur Nadir Karakulak, Erol Tulumen, Oya Ozdemir, Fatma Inanici, Kudret Aytemir, Giray Kabakci, Lale Tokgozoglu, Hilmi Ozkutlu, Ali Oto

Published in: Clinical Research in Cardiology | Issue 12/2010

Abstract

Objective

The aim of this study was to evaluate heart rate variability (HRV) and heart rate recovery (HRR) in otherwise healthy ankylosing spondlitis (AS) patients and control subjects.

Methods

A total of 28 patients with AS and 30 volunteers matched for age and sex were enrolled. All subjects underwent HRV analysis, exercise testing (ET), and transthoracic echocardiography. HRR indices were calculated by subtracting first, second, and third minute heart rates (HR) from the maximal HR.

Results

The AS and control groups were similar with respect to age (28.7 ± 5.7 vs. 29.3 ± 5.8 years), gender distribution [(male/female) 24/4 vs. 26/4], and left ventricular ejection fraction (LVEF) (63.8 ± 2.8% vs. 65.7 ± 3.6%). Mean HRR1 (24.8 ± 4.2 vs. 28.8 ± 5.5, P = 0.001) and HRR2 (42.0 ± 4.4 vs. 48.0 ± 6.3, P = 0.001) values were significantly higher in control group. SDNN, SDANN, RMSDD, and PNN50 significantly decreased; LF and LF/HF increased in AS patients compared with control subjects.

Conclusions

Patients with AS has lower HRR and HRV indices with respect to normal subjects. Cardiac autonomic functions might be involved in AS patients even in patients without cardiac symptoms.

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Title: Evaluation of cardiac autonomic functions in patients with ankylosing spondylitis via heart rate recovery and heart rate variability
Authors: Ergun Baris Kaya
Sercan Okutucu
Hakan Aksoy
Ugur Nadir Karakulak
Erol Tulumen
Oya Ozdemir
Fatma Inanici
Kudret Aytemir
Giray Kabakci
Lale Tokgozoglu
Hilmi Ozkutlu
Ali Oto
Publication date: 01-12-2010
Publisher: Springer-Verlag
Published in: Clinical Research in Cardiology / Issue 12/2010
Print ISSN: 1861-0684
Electronic ISSN: 1861-0692
DOI: https://doi.org/10.1007/s00392-010-0187-x

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Evaluation of cardiac autonomic functions in patients with ankylosing spondylitis via heart rate recovery and heart rate variability

Abstract

Objective

Methods

Results

Conclusions

Keynote webinar | Spotlight on medication adherence

Springer Medicine

Abstract

Objective

Methods

Results

Conclusions

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