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Odontology
Published in: Odontology 1/2024

Open Access 11-07-2023 | Etidronic Acid | Review Article

Effectiveness of continuous chelation irrigation protocol in endodontics: a scoping review of laboratory studies

Authors: Giusy Rita Maria La Rosa, Gianluca Plotino, Venkateshbabu Nagendrababu, Eugenio Pedullà

Published in: Odontology | Issue 1/2024

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Abstract

This scoping review aimed to synthesize and explore the current boundaries and limitations of laboratory research on the effectiveness of continuous chelation irrigation protocol in endodontics. This scoping review was reported according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) Extension for Scoping Reviews. Literature search was conducted on Pubmed and Scopus to identify all laboratory studies evaluating smear layer and hard-tissue debris removal or, antimicrobial efficacy, or dentine erosion induced by continuous chelation. Two independent reviewers performed the all review steps and the relevant items were recorded. Seventy-seven potentially relevant studies were identified. Finally, 23 laboratory studies met the eligibility criteria for qualitative synthesis. Seven studies focused on the smear layer/debris removal outcome, 10 on antimicrobial activity, and 10 on dentine erosion. In general, the continuous chelation protocol was equally or more effective in the cleanliness of root canals and antimicrobial activity compared with traditional sequential protocol. In addition, etidronate solutions seemed to be milder chelating agents compared to those with EDTA, thus resulting in reduced or no dentine erosion and roughness modification. Yet, the methodological differences among the included studies limit the results’ generalizability. The continuous chelation seems to be equally or more effective in all investigated outcomes when compared with the traditional sequential protocol. The methodological variability among the studies and shortcomings in the methods employed limit the generalizability and clinical relevance of the results. Standardized laboratory conditions combined with reliable three-dimensional investigation approaches are necessary to obtain clinically informative findings.
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Metadata
Title
Effectiveness of continuous chelation irrigation protocol in endodontics: a scoping review of laboratory studies
Authors
Giusy Rita Maria La Rosa
Gianluca Plotino
Venkateshbabu Nagendrababu
Eugenio Pedullà
Publication date
11-07-2023
Publisher
Springer Nature Singapore
Keyword
Etidronic Acid
Published in
Odontology / Issue 1/2024
Print ISSN: 1618-1247
Electronic ISSN: 1618-1255
DOI
https://doi.org/10.1007/s10266-023-00835-8

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