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01-03-2019 | Original Contribution

Estimated daily quercetin intake and association with the prevalence of type 2 diabetes mellitus in Chinese adults

Authors: Zhanxin Yao, Yeqing Gu, Qing Zhang, Li Liu, Ge Meng, Hongmei Wu, Yang Xia, Xue Bao, Hongbin Shi, Shaomei Sun, Xing Wang, Ming Zhou, Qiyu Jia, Yuntang Wu, Kun Song, Weina Gao, Changjiang Guo, Kaijun Niu

Published in: European Journal of Nutrition | Issue 2/2019

Abstract

Purpose

Quercetin is one of potential antidiabetic substances because of its powerful antioxidant and anti-inflammatory actions. The purpose of this study is to estimate daily quercetin intake and assess the relationship between dietary quercetin intake and the prevalence of type 2 diabetes mellitus (T2DM) in a Chinese population.

Methods

Dietary intake was investigated by a validated 100-item food frequency questionnaire. Daily intakes of quercetin and nutrients were calculated accordingly. T2DM was diagnosed based on the criteria of the American Diabetes Association. Adjusted logistic regression models were used to analyze the relationship between the quartiles of quercetin intake and the prevalence of T2DM.

Results

The prevalences of T2DM were 8.35% in men and 4.68% in women. The main food sources of quercetin were apple, orange, and green tea. Daily intake of quercetin was 20.9 ± 2.32 mg/day (mean ± SD). After adjusting for potentially confounding factors, the odds ratios (95% CI) for T2DM across the ascending quartiles of quercetin intake were: 1.00 (reference), 0.75 (0.60–0.95), 0.76 (0.59–0.99), and 0.63 (0.51–0.94).

Conclusions

The results of the present study showed that quercetin intake was inversely related to the prevalence of T2DM in the Chinese population, suggesting a protective effect of quercetin in the development of T2DM.

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Title: Estimated daily quercetin intake and association with the prevalence of type 2 diabetes mellitus in Chinese adults
Authors: Zhanxin Yao
Yeqing Gu
Qing Zhang
Li Liu
Ge Meng
Hongmei Wu
Yang Xia
Xue Bao
Hongbin Shi
Shaomei Sun
Xing Wang
Ming Zhou
Qiyu Jia
Yuntang Wu
Kun Song
Weina Gao
Changjiang Guo
Kaijun Niu
Publication date: 01-03-2019
Publisher: Springer Berlin Heidelberg
Published in: European Journal of Nutrition / Issue 2/2019
Print ISSN: 1436-6207
Electronic ISSN: 1436-6215
DOI: https://doi.org/10.1007/s00394-018-1713-2

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