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Digestive Diseases and Sciences
Published in: Digestive Diseases and Sciences 7/2019

01-07-2019 | Esophagogastroduodenoscopy | Case Report

Case Report of a Proposed, Novel, Endoscopic “Whitehead Pimple” Sign of Ectopic Esophageal Sebaceous Glands Based on Their Mimicking the Dermatologic and Histopathologic Characteristics of Cutaneous Whitehead Pimples/Closed Comedones

Authors: Amy Le, Mitual Amin, Mitchell S. Cappell

Published in: Digestive Diseases and Sciences | Issue 7/2019

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Excerpt

Endoscopic signs help characterize endoscopic lesions. The endoscopic appearance of esophageal ectopic sebaceous glands (ESGs/Fordyce lesions) has been described in several case reports [1, 2], but none have described its endoscopic appearance as potentially characteristic or mimicking a type of cutaneous sebaceous glands. This report describes that its endoscopic appearance and histopathology mimics that of cutaneous closed comedones (colloquially, whitehead pimples), explains the pathophysiology, and reports a novel potentially diagnostic endoscopic sign. …
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Marcial MA, Villafaña M. Esophageal ectopic sebaceous glands: endoscopic and histologic findings. Gastrointest Endosc. 1994;40:630.CrossRefPubMed
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Kim TH, Song JH, Kim TH, et al. A case of ectopic sebaceous glands in the esophagus. Korean J Helicobacter Up Gastrointest Res. 2012;12:249–251.CrossRef
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Vadva MD, Triadafilopoulos G. Glycogenic acanthosis of the esophagus and gastroesophageal reflux. J Clin Gastroenterol. 1993;17:79.CrossRefPubMed
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Stern Z, Sharon P, Ligumsky M, Levij IS, Rachmilewitz D. Glycogenic acanthosis of the esophagus. A benign but confusing endoscopic lesion. Am J Gastroenterol. 1980;74:261.PubMed
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Ghahremani GG, Rushovich AM. Glycogenic acanthosis of the esophagus: radiographic and pathologic features. Gastrointest Radiol. 1984;9:93.CrossRefPubMed
Metadata
Title
Case Report of a Proposed, Novel, Endoscopic “Whitehead Pimple” Sign of Ectopic Esophageal Sebaceous Glands Based on Their Mimicking the Dermatologic and Histopathologic Characteristics of Cutaneous Whitehead Pimples/Closed Comedones
Authors
Amy Le
Mitual Amin
Mitchell S. Cappell
Publication date
01-07-2019
Publisher
Springer US
Published in
Digestive Diseases and Sciences / Issue 7/2019
Print ISSN: 0163-2116
Electronic ISSN: 1573-2568
DOI
https://doi.org/10.1007/s10620-019-05487-9

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