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Journal of Gastroenterology
Published in: Journal of Gastroenterology 4/2018

01-04-2018 | Review

Esophageal motility disorders: new perspectives from high-resolution manometry and histopathology

Authors: Hiroki Sato, Kazuya Takahashi, Ken-ichi Mizuno, Satoru Hashimoto, Junji Yokoyama, Go Hasegawa, Shuji Terai

Published in: Journal of Gastroenterology | Issue 4/2018

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Abstract

High-resolution manometry (HRM) and peroral endoscopic myotomy (POEM) have contributed significantly to the field of esophageal motility disorders in recent years. The development of HRM has categorized various esophageal motility disorders with a focus on a diverse range of manometric anomalies. Additionally, the Chicago classification criteria is widely used for manometric diagnosis. Moreover, POEM was introduced as a minimally invasive radical therapy for achalasia and shows promise for other spastic esophageal motility disorders as well. POEM has also enabled a transluminal endoscopic approach for determining the histology of the esophageal muscle layer, which is expected to assist in elucidating the etiology of disorders associated with esophageal motility. The purpose of this review is to update the diagnosis, pathology, and treatment of esophageal motility disorders, with a focus on the recent advances in this field.
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Metadata
Title
Esophageal motility disorders: new perspectives from high-resolution manometry and histopathology
Authors
Hiroki Sato
Kazuya Takahashi
Ken-ichi Mizuno
Satoru Hashimoto
Junji Yokoyama
Go Hasegawa
Shuji Terai
Publication date
01-04-2018
Publisher
Springer Japan
Published in
Journal of Gastroenterology / Issue 4/2018
Print ISSN: 0944-1174
Electronic ISSN: 1435-5922
DOI
https://doi.org/10.1007/s00535-017-1413-3

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